Hasil Pencarian - Timothy J. Egan

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  1. 1
    Recent Advances in the Discovery of Haem-Targeting Drugs for Malaria and Schistosomiasis

    Recent Advances in the Discovery of Haem-Targeting Drugs for Malaria and Schistosomiasis oleh Katherine A. de Villiers, Timothy J. Egan

    Diterbitkan 2009-08-01
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  2. 2
    Identifying inhibitors of β-haematin formation with activity against chloroquine-resistant Plasmodium falciparum malaria parasites via virtual screening approaches

    Identifying inhibitors of β-haematin formation with activity against chloroquine-resistant Plasmodium falciparum malaria parasites via virtual screening approaches oleh Leah Amod, Roxanne Mohunlal, Nicole Teixeira, Timothy J. Egan, Kathryn J. Wicht

    Diterbitkan 2023-02-01
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  3. 3
    Lapatinib, Nilotinib and Lomitapide Inhibit Haemozoin Formation in Malaria Parasites

    Lapatinib, Nilotinib and Lomitapide Inhibit Haemozoin Formation in Malaria Parasites oleh Ana Carolina C. de Sousa, Keletso Maepa, Jill M. Combrinck, Timothy J. Egan

    Diterbitkan 2020-03-01
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  4. 4
    Virtual screening as a tool to discover new β-haematin inhibitors with activity against malaria parasites

    Virtual screening as a tool to discover new β-haematin inhibitors with activity against malaria parasites oleh Ana Carolina C. de Sousa, Jill M. Combrinck, Keletso Maepa, Timothy J. Egan

    Diterbitkan 2020-02-01
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  5. 5
    Increase on the initial soluble heme levels in acidic conditions is an important mechanism for spontaneous heme crystallization in vitro.

    Increase on the initial soluble heme levels in acidic conditions is an important mechanism for spontaneous heme crystallization in vitro. oleh Renata Stiebler, Anh N Hoang, Timothy J Egan, David W Wright, Marcus F Oliveira

    Diterbitkan 2010-09-01
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  6. 6
    Unsaturated glycerophospholipids mediate heme crystallization: biological implications for hemozoin formation in the kissing bug Rhodnius prolixus.

    Unsaturated glycerophospholipids mediate heme crystallization: biological implications for hemozoin formation in the kissing bug Rhodnius prolixus. oleh Renata Stiebler, David Majerowicz, Jens Knudsen, Katia C Gondim, David W Wright, Timothy J Egan, Marcus F Oliveira

    Diterbitkan 2014-01-01
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  7. 7
    Identification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity

    Identification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity oleh Rebecca D. Sandlin, Kim Y. Fong, Kathryn J. Wicht, Holly M. Carrell, Timothy J. Egan, David W. Wright

    Diterbitkan 2014-12-01
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  8. 8
    Interplay between Plasmodium falciparum haemozoin and l-arginine: implication for nitric oxide production

    Interplay between Plasmodium falciparum haemozoin and l-arginine: implication for nitric oxide production oleh Yolanda Corbett, Sarah D’Alessandro, Silvia Parapini, Diletta Scaccabarozzi, Parisa Kalantari, Stefania Zava, Flavio Giavarini, Donatella Caruso, Irma Colombo, Timothy J. Egan, Nicoletta Basilico

    Diterbitkan 2018-12-01
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  9. 9
    Naphthylisoquinoline alkaloids, validated as hit multistage antiplasmodial natural products

    Naphthylisoquinoline alkaloids, validated as hit multistage antiplasmodial natural products oleh Phanankosi Moyo, William Shamburger, Mariëtte E. van der Watt, Janette Reader, Ana Carolina C. de Sousa, Timothy J. Egan, Vinesh J. Maharaj, Gerhard Bringmann, Lyn-Marie Birkholtz

    Diterbitkan 2020-08-01
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  10. 10
    Discovery of antiplasmodial pyridine carboxamides and thiocarboxamides

    Discovery of antiplasmodial pyridine carboxamides and thiocarboxamides oleh Alexa Redway, Christina Spry, Ainka Brown, Ursula Wiedemann, Imam Fathoni, Larnelle F. Garnie, Deyun Qiu, Timothy J. Egan, Adele M. Lehane, Yvette Jackson, Kevin J. Saliba, Nadale Downer-Riley

    Diterbitkan 2024-08-01
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  11. 11
    In vitro antiplasmodium and antitrypanosomal activities, β-haematin formation inhibition, molecular docking and DFT computational studies of quinoline-urea-benzothiazole hybrids

    In vitro antiplasmodium and antitrypanosomal activities, β-haematin formation inhibition, molecular docking and DFT computational studies of quinoline-urea-benzothiazole hybrids oleh Oluwatoba E. Oyeneyin, Rashmika Moodley, Chakes Mashaba, Larnelle F. Garnie, Damilola A. Omoboyowa, Goitsemodimo H. Rakodi, Mabuatsela V. Maphoru, Mohamed O. Balogun, Heinrich C. Hoppe, Timothy J. Egan, Matshawandile Tukulula

    Diterbitkan 2024-10-01
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  12. 12
    Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols.

    Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols. oleh Juliana B R Corrêa Soares, Diego Menezes, Marcos A Vannier-Santos, Antonio Ferreira-Pereira, Giulliana T Almeida, Thiago M Venancio, Sergio Verjovski-Almeida, Vincent K Zishiri, David Kuter, Roger Hunter, Timothy J Egan, Marcus F Oliveira

    Diterbitkan 2009-01-01
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  13. 13
    A Variant PfCRT Isoform Can Contribute to <italic toggle="yes">Plasmodium falciparum</italic> Resistance to the First-Line Partner Drug Piperaquine

    A Variant PfCRT Isoform Can Contribute to <italic toggle="yes">Plasmodium falciparum</italic> Resistance to the First-Line Partner Drug Piperaquine oleh Satish K. Dhingra, Devasha Redhi, Jill M. Combrinck, Tomas Yeo, John Okombo, Philipp P. Henrich, Annie N. Cowell, Purva Gupta, Matthew L. Stegman, Jonathan M. Hoke, Roland A. Cooper, Elizabeth Winzeler, Sachel Mok, Timothy J. Egan, David A. Fidock

    Diterbitkan 2017-07-01
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  14. 14
    Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology.

    Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiol... oleh Stanislaw J Gabryszewski, Satish K Dhingra, Jill M Combrinck, Ian A Lewis, Paul S Callaghan, Matthew R Hassett, Amila Siriwardana, Philipp P Henrich, Andrew H Lee, Nina F Gnädig, Lise Musset, Manuel Llinás, Timothy J Egan, Paul D Roepe, David A Fidock

    Diterbitkan 2016-11-01
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  15. 15
    Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

    Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway oleh Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler

    Diterbitkan 2020-04-01
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