Contribution of parasite and host genotype to immunopathology of schistosome infections by Kathrin S. Jutzeler, Winka Le Clec’h, Frédéric D. Chevalier, Timothy J. C. Anderson

Get full text

No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host by Winka Le Clec’h, Frédéric D. Chevalier, Kathrin Jutzeler, Timothy J. C. Anderson

Get full text

The distribution of intestinal helminth infections in a rural village in Guatemala by Timothy J. C. Anderson, Claire A. Zizza, Guisela M. Leche, Marilyn E. Scott, Noel W. Solomons

Get full text

Striking differences in virulence, transmission and sporocyst growth dynamics between two schistosome populations by Winka Le Clecʼh, Robbie Diaz, Frédéric D. Chevalier, Marina McDew-White, Timothy J. C. Anderson

Get full text

Identity-by-descent with uncertainty characterises connectivity of Plasmodium falciparum populations on the Colombian-Pacific coast. by Aimee R Taylor, Diego F Echeverry, Timothy J C Anderson, Daniel E Neafsey, Caroline O Buckee

Get full text

Genetic architecture of transmission stage production and virulence in schistosome parasites by Winka Le Clec’h, Frédéric D. Chevalier, Marina McDew-White, Vinay Menon, Grace-Ann Arya, Timothy J.C. Anderson

Get full text

Landscape genetics reveals focal transmission of a human macroparasite. by Charles D Criscione, Joel D Anderson, Dan Sudimack, Janardan Subedi, Ram P Upadhayay, Bharat Jha, Kimberly D Williams, Sarah Williams-Blangero, Timothy J C Anderson

Get full text

Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent. by Aimee R Taylor, Stephen F Schaffner, Gustavo C Cerqueira, Standwell C Nkhoma, Timothy J C Anderson, Kanlaya Sriprawat, Aung Pyae Phyo, François Nosten, Daniel E Neafsey, Caroline O Buckee

Get full text

Prospecting for Zoonotic Pathogens by Using Targeted DNA Enrichment by Egie E. Enabulele, Winka Le Clec’h, Emma K. Roberts, Cody W. Thompson, Molly M. McDonough, Adam W. Ferguson, Robert D. Bradley, Timothy J. C. Anderson, Roy N. Platt

Get full text

Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates by Abigail R. Tirrell, Katelyn M. Vendrely, Lisa A. Checkley, Sage Z. Davis, Marina McDew-White, Ian H. Cheeseman, Ashley M. Vaughan, François H. Nosten, Timothy J. C. Anderson, Michael T. Ferdig

Get full text

Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum? by Anastasia R. Rugel, Meghan A. Guzman, Alexander B. Taylor, Frédéric D. Chevalier, Reid S. Tarpley, Stanton F. McHardy, Xiaohang Cao, Stephen P. Holloway, Timothy J.C. Anderson, P. John Hart, Philip T. LoVerde

Get full text

Schistosome Sulfotransferases: Mode of Action, Expression and Localization by Meghan A. Guzman, Anastasia Rugel, Sevan N. Alwan, Reid Tarpley, Alexander B. Taylor, Frédéric D. Chevalier, George R. Wendt, James J. Collins, Timothy J. C. Anderson, Stanton F. McHardy, Philip T. LoVerde

Get full text

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine. by Alexander B Taylor, Livia Pica-Mattoccia, Chiara M Polcaro, Enrica Donati, Xiaohang Cao, Annalisa Basso, Alessandra Guidi, Anastasia R Rugel, Stephen P Holloway, Timothy J C Anderson, P John Hart, Donato Cioli, Philip T LoVerde

Get full text

An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans. by Meghan A Guzman, Anastasia R Rugel, Reid S Tarpley, Sevan N Alwan, Frédéric D Chevalier, Dmytro P Kovalskyy, Xiaohang Cao, Stephen P Holloway, Timothy J C Anderson, Alexander B Taylor, Stanton F McHardy, Philip T LoVerde

Get full text

Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance by Gustavo C. Cerqueira, Ian H. Cheeseman, Steve F. Schaffner, Shalini Nair, Marina McDew-White, Aung Pyae Phyo, Elizabeth A. Ashley, Alexandre Melnikov, Peter Rogov, Bruce W. Birren, François Nosten, Timothy J. C. Anderson, Daniel E. Neafsey

Get full text

Resolving drug selection and migration in an inbred South American Plasmodium falciparum population with identity-by-descent analysis. by Manuela Carrasquilla, Angela M Early, Aimee R Taylor, Angélica Knudson Ospina, Diego F Echeverry, Timothy J C Anderson, Elvira Mancilla, Samanda Aponte, Pablo Cárdenas, Caroline O Buckee, Julian C Rayner, Fabián E Sáenz, Daniel E Neafsey, Vladimir Corredor

Get full text

The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput by Sage Z. Davis, Puspendra P. Singh, Katelyn M. Vendrely, Douglas A. Shoue, Lisa A. Checkley, Marina McDew-White, Katrina A. Button-Simons, Zione Cassady, Mackenzie A. C. Sievert, Gabriel J. Foster, François H. Nosten, Timothy J. C. Anderson, Michael T. Ferdig

Get full text

The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice by Katrina A. Button-Simons, Sudhir Kumar, Nelly Carmago, Meseret T. Haile, Catherine Jett, Lisa A. Checkley, Spencer Y. Kennedy, Richard S. Pinapati, Douglas A. Shoue, Marina McDew-White, Xue Li, François H. Nosten, Stefan H. Kappe, Timothy J. C. Anderson, Jeanne Romero-Severson, Michael T. Ferdig, Scott J. Emrich, Ashley M. Vaughan, Ian H. Cheeseman

Get full text

Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment. by Frédéric D Chevalier, Winka Le Clec'h, Marina McDew-White, Vinay Menon, Meghan A Guzman, Stephen P Holloway, Xiaohang Cao, Alexander B Taylor, Safari Kinung'hi, Anouk N Gouvras, Bonnie L Webster, Joanne P Webster, Aidan M Emery, David Rollinson, Amadou Garba Djirmay, Khalid M Al Mashikhi, Salem Al Yafae, Mohamed A Idris, Hélène Moné, Gabriel Mouahid, P John Hart, Philip T LoVerde, Timothy J C Anderson

Get full text

A Plasmodium falciparum genetic cross reveals the contributions of pfcrt and plasmepsin II/III to piperaquine drug resistance by John Kane, Xue Li, Sudhir Kumar, Katrina A. Button-Simons, Katelyn M. Vendrely Brenneman, Haley Dahlhoff, Mackenzie A. C. Sievert, Lisa A. Checkley, Douglas A. Shoue, Puspendra P. Singh, Biley A. Abatiyow, Meseret T. Haile, Shalini Nair, Ann Reyes, Rupam Tripura, Thomas J. Peto, Dysoley Lek, Angana Mukherjee, Stefan H. I. Kappe, Mehul Dhorda, Standwell C. Nkhoma, Ian H. Cheeseman, Ashley M. Vaughan, Timothy J. C. Anderson, Michael T. Ferdig

Get full text