Hasil Pencarian - Thomas MacCarthy

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  1. 1
    Characterization of DNA G-Quadruplex Structures in Human Immunoglobulin Heavy Variable (IGHV) Genes

    Characterization of DNA G-Quadruplex Structures in Human Immunoglobulin Heavy Variable (IGHV) Genes oleh Catherine Tang, Thomas MacCarthy, Thomas MacCarthy

    Diterbitkan 2021-05-01
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  2. 2
    Correlations in Somatic Hypermutation Between Sites in IGHV Genes Can Be Explained by Interactions Between AID and/or Polη Hotspots

    Correlations in Somatic Hypermutation Between Sites in IGHV Genes Can Be Explained by Interactions Between AID and/or Polη Hotspots oleh Artem Krantsevich, Catherine Tang, Thomas MacCarthy, Thomas MacCarthy

    Diterbitkan 2021-02-01
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  3. 3
    Antagonistic Coevolution Drives Whack-a-Mole Sensitivity in Gene Regulatory Networks.

    Antagonistic Coevolution Drives Whack-a-Mole Sensitivity in Gene Regulatory Networks. oleh Jeewoen Shin, Thomas MacCarthy

    Diterbitkan 2015-10-01
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  4. 4
    The preferred nucleotide contexts of the AID/APOBEC cytidine deaminases have differential effects when mutating retrotransposon and virus sequences compared to host genes.

    The preferred nucleotide contexts of the AID/APOBEC cytidine deaminases have differential effects when mutating retrotransposon and virus sequences compared to host genes. oleh Jeffrey Chen, Thomas MacCarthy

    Diterbitkan 2017-03-01
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  5. 5
    Epigenetics decouples mutational from environmental robustness. Did it also facilitate multicellularity?

    Epigenetics decouples mutational from environmental robustness. Did it also facilitate multicellularity? oleh Saurabh Gombar, Thomas MacCarthy, Aviv Bergman

    Diterbitkan 2014-03-01
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  6. 6
    Deep learning model of somatic hypermutation reveals importance of sequence context beyond hotspot targeting

    Deep learning model of somatic hypermutation reveals importance of sequence context beyond hotspot targeting oleh Catherine Tang, Artem Krantsevich, Thomas MacCarthy

    Diterbitkan 2022-01-01
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  7. 7
    The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure

    The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure oleh Maxwell Shapiro, Stephen Meier, Thomas MacCarthy

    Diterbitkan 2018-05-01
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  8. 8
    Correction to: The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure

    Correction to: The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure oleh Maxwell Shapiro, Stephen Meier, Thomas MacCarthy

    Diterbitkan 2018-07-01
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  9. 9
    Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection.

    Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection. oleh Maxwell Shapiro, Laurie T Krug, Thomas MacCarthy

    Diterbitkan 2021-04-01
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  10. 10
    The underlying molecular and network level mechanisms in the evolution of robustness in gene regulatory networks.

    The underlying molecular and network level mechanisms in the evolution of robustness in gene regulatory networks. oleh Mario Pujato, Thomas MacCarthy, Andras Fiser, Aviv Bergman

    Diterbitkan 2013-01-01
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  11. 11
    Interpretable deep learning reveals the role of an E-box motif in suppressing somatic hypermutation of AGCT motifs within human immunoglobulin variable regions

    Interpretable deep learning reveals the role of an E-box motif in suppressing somatic hypermutation of AGCT motifs within human immunoglobulin variable regions oleh Abhik Tambe, Thomas MacCarthy, Rushad Pavri, Rushad Pavri

    Diterbitkan 2024-05-01
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  12. 12
    Evolvability of cancer-associated genes under APOBEC3A/B selection

    Evolvability of cancer-associated genes under APOBEC3A/B selection oleh Joon-Hyun Song, Liliana M. Dávalos, Thomas MacCarthy, Mehdi Damaghi

    Diterbitkan 2024-04-01
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  13. 13
    Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging.

    Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging. oleh Aviv Bergman, Gil Atzmon, Kenny Ye, Thomas MacCarthy, Nir Barzilai

    Diterbitkan 2007-08-01
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  14. 14
    Regulatory evolution and voltage-gated ion channel expression in squid axon: selection-mutation balance and fitness cliffs.

    Regulatory evolution and voltage-gated ion channel expression in squid axon: selection-mutation balance and fitness cliffs. oleh Min Kim, Don McKinnon, Thomas MacCarthy, Barbara Rosati, David McKinnon

    Diterbitkan 2015-01-01
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  15. 15
    AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes

    AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes oleh Catherine Tang, Davide Bagnara, Davide Bagnara, Nicholas Chiorazzi, Matthew D. Scharff, Thomas MacCarthy

    Diterbitkan 2020-04-01
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  16. 16
    The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia.

    The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia. oleh Chaohui Yuan, Charles C Chu, Xiao-Jie Yan, Davide Bagnara, Nicholas Chiorazzi, Thomas MacCarthy

    Diterbitkan 2017-01-01
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  17. 17
    A Bayesian model based computational analysis of the relationship between bisulfite accessible single-stranded DNA in chromatin and somatic hypermutation of immunoglobulin genes.

    A Bayesian model based computational analysis of the relationship between bisulfite accessible single-stranded DNA in chromatin and somatic hypermutation of immunoglobulin genes. oleh Guojun Yu, Yingru Wu, Zhi Duan, Catherine Tang, Haipeng Xing, Matthew D Scharff, Thomas MacCarthy

    Diterbitkan 2021-09-01
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  18. 18
    Recombinase-Mediated Cassette Exchange as a Novel Method To Study Somatic Hypermutation in Ramos Cells

    Recombinase-Mediated Cassette Exchange as a Novel Method To Study Somatic Hypermutation in Ramos Cells oleh Linda B. Baughn, Susan L. Kalis, Thomas MacCarthy, Lirong Wei, Manxia Fan, Aviv Bergman, Matthew D. Scharff

    Diterbitkan 2011-11-01
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  19. 19
    Beta human papillomavirus 8E6 promotes alternative end joining

    Beta human papillomavirus 8E6 promotes alternative end joining oleh Changkun Hu, Taylor Bugbee, Rachel Palinski, Ibukun A Akinyemi, Michael T McIntosh, Thomas MacCarthy, Sumita Bhaduri-McIntosh, Nicholas Wallace

    Diterbitkan 2023-01-01
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  20. 20
    Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity

    Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity oleh Zhixin Jing, Phillip Galbo, Luis Ovando, Megan Demouth, Skylar Welte, Rosa Park, Kartik Chandran, Yinghao Wu, Thomas MacCarthy, Deyou Zheng, David Fooksman

    Diterbitkan 2024-06-01
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