Hasil Pencarian - Thomas M. Roberts

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  1. 1
    The Mechanisms Underlying PTEN Loss in Human Tumors Suggest Potential Therapeutic Opportunities

    The Mechanisms Underlying PTEN Loss in Human Tumors Suggest Potential Therapeutic Opportunities oleh Hyeyoun Chang, Zhenying Cai, Thomas M. Roberts

    Diterbitkan 2019-11-01
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  2. 2
    Rac1-mediated membrane raft localization of PI3K/p110β is required for its activation by GPCRs or PTEN loss

    Rac1-mediated membrane raft localization of PI3K/p110β is required for its activation by GPCRs or PTEN loss oleh Onur Cizmecioglu, Jing Ni, Shaozhen Xie, Jean J Zhao, Thomas M Roberts

    Diterbitkan 2016-10-01
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  3. 3
    A Conditional Dependency on MELK for the Proliferation of Triple-Negative Breast Cancer Cells

    A Conditional Dependency on MELK for the Proliferation of Triple-Negative Breast Cancer Cells oleh Yubao Wang, Ben B. Li, Jing Li, Thomas M. Roberts, Jean J. Zhao

    Diterbitkan 2018-11-01
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  4. 4
    The role of the PIK3CA gene in the development and aging of the brain

    The role of the PIK3CA gene in the development and aging of the brain oleh Shaozhen Xie, Jing Ni, Hanbing Guo, Victor Luu, Yanzhi Wang, Jean J. Zhao, Thomas M. Roberts

    Diterbitkan 2021-01-01
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  5. 5
    RNAi-Based Approaches for Pancreatic Cancer Therapy

    RNAi-Based Approaches for Pancreatic Cancer Therapy oleh Min Ju Kim, Hyeyoun Chang, Gihoon Nam, Youngji Ko, Sun Hwa Kim, Thomas M. Roberts, Ju Hee Ryu

    Diterbitkan 2021-10-01
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  6. 6
    CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells

    CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells oleh Jing Zhang, Xueliang Gao, Fabienne Schmit, Guillaume Adelmant, Michael J. Eck, Jarrod A. Marto, Jean J. Zhao, Thomas M. Roberts

    Diterbitkan 2017-07-01
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  7. 7
    The identification of zebrafish mutants showing alterations in senescence-associated biomarkers.

    The identification of zebrafish mutants showing alterations in senescence-associated biomarkers. oleh Shuji Kishi, Peter E Bayliss, Junzo Uchiyama, Eriko Koshimizu, Jie Qi, Purushothama Nanjappa, Shintaro Imamura, Asiful Islam, Donna Neuberg, Adam Amsterdam, Thomas M Roberts

    Diterbitkan 2008-08-01
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  8. 8
    PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer

    PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer oleh Jennifer M. Spangle, Koen M. Dreijerink, Anna C. Groner, Hailing Cheng, Carolynn E. Ohlson, Jaime Reyes, Charles Y. Lin, James Bradner, Jean J. Zhao, Thomas M. Roberts, Myles Brown

    Diterbitkan 2016-06-01
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  9. 9
    K-RAS mutant pancreatic tumors show higher sensitivity to MEK than to PI3K inhibition in vivo.

    K-RAS mutant pancreatic tumors show higher sensitivity to MEK than to PI3K inhibition in vivo. oleh Irmgard Hofmann, Andreas Weiss, Gaelle Elain, Maria Schwaederle, Dario Sterker, Vincent Romanet, Tobias Schmelzle, Albert Lai, Saskia M Brachmann, Mohamed Bentires-Alj, Thomas M Roberts, William R Sellers, Francesco Hofmann, Sauveur-Michel Maira

    Diterbitkan 2012-01-01
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  10. 10
    Spermidine‐Functionalized Injectable Hydrogel Reduces Inflammation and Enhances Healing of Acute and Diabetic Wounds In Situ

    Spermidine‐Functionalized Injectable Hydrogel Reduces Inflammation and Enhances Healing of Acute and Diabetic Wounds In Situ oleh Qianqian Wu, Runjiao Yang, Wenxuan Fan, Li Wang, Jing Zhan, Tingting Cao, Qiming Liu, Xianshu Piao, Yinghui Zhong, Wenxian Zhao, Shuhan Zhang, Jiaao Yu, Song Liang, Thomas M. Roberts, Bingdi Wang, Zhenning Liu

    Diterbitkan 2024-06-01
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  11. 11
    A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis.

    A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. oleh Shintaro Imamura, Junzo Uchiyama, Eriko Koshimizu, Jun-Ichi Hanai, Christina Raftopoulou, Ryan D Murphey, Peter E Bayliss, Yoichi Imai, Caroline Erter Burns, Kenkichi Masutomi, Sarantis Gagos, Leonard I Zon, Thomas M Roberts, Shuji Kishi

    Diterbitkan 2008-01-01
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  12. 12
    Statin-mediated inhibition of RAS prenylation activates ER stress to enhance the immunogenicity of KRAS mutant cancer

    Statin-mediated inhibition of RAS prenylation activates ER stress to enhance the immunogenicity of KRAS mutant cancer oleh Su Jeong Song, Seohyun Kim, Seong A Kim, Gi-Hoon Nam, Gi Beom Kim, Yoonjeong Choi, Minsu Kwon, Cherlhyun Jeong, Hanul Jung, Eunbyeol Ko, Yeji Lee, Jihoon Han, Jiwan Woo, Yakdol Cho, Seung-Yoon Park, Thomas M. Roberts, Yong Beom Cho

    Diterbitkan 2021-07-01
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  13. 13
    STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer

    STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer oleh Changli Qian, Gordon J Freeman, Tao Jiang, Ursula Matulonis, Ziying Lin, Hye-Jung Kim, Anniina Färkkilä, Hua Yu, Xin Cheng, Antons Martincuks, Joyce F Liu, Qiwei Wang, Liya Ding, Michael J Kearns, Shaozhen Xie, Inga-Maria Launonen, Thomas M Roberts, Jean J Zhao

    Diterbitkan 2023-01-01
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  14. 14
    PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer

    PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer oleh Liya Ding, Hye-Jung Kim, Qiwei Wang, Michael Kearns, Tao Jiang, Carolynn E. Ohlson, Ben B. Li, Shaozhen Xie, Joyce F. Liu, Elizabeth H. Stover, Brooke E. Howitt, Roderick T. Bronson, Suzan Lazo, Thomas M. Roberts, Gordon J. Freeman, Panagiotis A. Konstantinopoulos, Ursula A. Matulonis, Jean J. Zhao

    Diterbitkan 2018-12-01
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  15. 15
    STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer

    STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer oleh Qiwei Wang, Johann S. Bergholz, Liya Ding, Ziying Lin, Sheheryar K. Kabraji, Melissa E. Hughes, Xiadi He, Shaozhen Xie, Tao Jiang, Weihua Wang, Jason J. Zoeller, Hye-Jung Kim, Thomas M. Roberts, Panagiotis A. Konstantinopoulos, Ursula A. Matulonis, Deborah A. Dillon, Eric P. Winer, Nancy U. Lin, Jean J. Zhao

    Diterbitkan 2022-05-01
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