FAD Mutations in Presenilin-1 or Amyloid Precursor Protein Decrease the Efficacy of a γ-Secretase Inhibitor: Evidence for Direct Involvement of PS1 in the γ-Secretase Cleavage Comp... oleh Weiming Xia, Beth L. Ostaszewski, W.Taylor Kimberly, Talat Rahmati, Chad L. Moore, Michael S. Wolfe, Dennis J. Selkoe