Hasil Pencarian - Susumu S. Kobayashi

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  1. 1
    Mathematical analysis identifies the optimal treatment strategy for epidermal growth factor receptor-mutated non-small cell lung cancer

    Mathematical analysis identifies the optimal treatment strategy for epidermal growth factor receptor-mutated non-small cell lung cancer oleh Qian Yu, Susumu S. Kobayashi, Hiroshi Haeno

    Diterbitkan 2023-09-01
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  2. 2
    EGFR-D770>GY and Other Rare EGFR Exon 20 Insertion Mutations with a G770 Equivalence Are Sensitive to Dacomitinib or Afatinib and Responsive to EGFR Exon 20 Insertion Mutant-Active Inhibitors in Preclinical Models and Clinical Scenarios

    EGFR-D770>GY and Other Rare EGFR Exon 20 Insertion Mutations with a G770 Equivalence Are Sensitive to Dacomitinib or Afatinib and Responsive to EGFR Exon 20 Insertion Mutant-Active... oleh Ikei S. Kobayashi, Hollis Viray, Deepa Rangachari, Susumu S. Kobayashi, Daniel B. Costa

    Diterbitkan 2021-12-01
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  3. 3
    Differential Pattern of Resistance and Sensitivity to Different Classes of MET Inhibitors for MET-Amplified Tumors With MET-D1228X or MET-Y1230X Mutations

    Differential Pattern of Resistance and Sensitivity to Different Classes of MET Inhibitors for MET-Amplified Tumors With MET-D1228X or MET-Y1230X Mutations oleh Andrew J. Piper-Vallillo, MD, Susumu S. Kobayashi, MD, PhD, Daniel B. Costa, MD, PhD

    Diterbitkan 2021-03-01
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  4. 4
    Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer

    Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer oleh Motohiro Izumi, Masanori Fujii, Ikei S. Kobayashi, Vivian Ho, Yukie Kashima, Hibiki Udagawa, Daniel B. Costa, Susumu S. Kobayashi

    Diterbitkan 2024-08-01
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  5. 5
    Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα

    Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα oleh Radhakrishnan Sridhar, Hisashi Takei, Riyaz Syed, Ikei S. Kobayashi, Liu Bee Hui, Ahmed Kamal, Daniel G. Tenen, Susumu S. Kobayashi

    Diterbitkan 2018-08-01
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  6. 6
    Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells

    Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells oleh Yumi Fujimoto, Tomoko Yamamori Morita, Akihiro Ohashi, Hiroshi Haeno, Yumi Hakozaki, Masanori Fujii, Yukie Kashima, Susumu S. Kobayashi, Toru Mukohara

    Diterbitkan 2020-12-01
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  7. 7
    NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells

    NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells oleh Lívia Bassani Lins de Miranda, Keli Lima, Juan Luiz Coelho-Silva, Fabiola Traina, Susumu S. Kobayashi, João Agostinho Machado-Neto

    Diterbitkan 2022-10-01
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  8. 8
    HSP90 inhibition overcomes EGFR amplification‐induced resistance to third‐generation EGFR‐TKIs

    HSP90 inhibition overcomes EGFR amplification‐induced resistance to third‐generation EGFR‐TKIs oleh Sho Watanabe, Yasushi Goto, Hiroyuki Yasuda, Takashi Kohno, Noriko Motoi, Yuichiro Ohe, Hiroyoshi Nishikawa, Susumu S. Kobayashi, Kazuyoshi Kuwano, Yosuke Togashi

    Diterbitkan 2021-03-01
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  9. 9
    Preclinical Characterization of Mobocertinib Highlights the Putative Therapeutic Window of This Novel EGFR Inhibitor to EGFR Exon 20 Insertion Mutations

    Preclinical Characterization of Mobocertinib Highlights the Putative Therapeutic Window of This Novel EGFR Inhibitor to EGFR Exon 20 Insertion Mutations oleh Pedro E.N.S. Vasconcelos, MS, Ikei S. Kobayashi, MD, PhD, Susumu S. Kobayashi, MD, PhD, Daniel B. Costa, MD, PhD

    Diterbitkan 2021-03-01
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  10. 10
    Acquired Resistance to Osimertinib Plus Savolitinib Is Mediated by MET-D1228 and MET-Y1230 Mutations in EGFR-Mutated MET-Amplified Lung Cancer

    Acquired Resistance to Osimertinib Plus Savolitinib Is Mediated by MET-D1228 and MET-Y1230 Mutations in EGFR-Mutated MET-Amplified Lung Cancer oleh Andrew J. Piper-Vallillo, MD, Brian T. Halbert, MD, Deepa Rangachari, MD, Susumu S. Kobayashi, MD, PhD, Daniel B. Costa, MD, PhD

    Diterbitkan 2020-11-01
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  11. 11
    CCAAT/enhancer binding protein β is dispensable for development of lung adenocarcinoma.

    CCAAT/enhancer binding protein β is dispensable for development of lung adenocarcinoma. oleh Yi Cai, Ayako Hirata, Sohei Nakayama, Paul A VanderLaan, Elena Levantini, Mihoko Yamamoto, Hideyo Hirai, Kwok-Kin Wong, Daniel B Costa, Hideo Watanabe, Susumu S Kobayashi

    Diterbitkan 2015-01-01
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  12. 12
    Altered distribution and function of NK-cell subsets lead to impaired tumor surveillance in JAK2V617F myeloproliferative neoplasms

    Altered distribution and function of NK-cell subsets lead to impaired tumor surveillance in JAK2V617F myeloproliferative neoplasms oleh Amanda Fernandes de Oliveira Costa, Leticia Olops Marani, Thiago Mantello Bianco, Adriana Queiroz Arantes, Izabela Aparecida Lopes, Diego Antonio Pereira-Martins, Leonardo Carvalho Palma, Priscila Santos Scheucher, Josiane Lilian dos Santos Schiavinato, Larissa Sarri Binelli, Cleide Araújo Silva, Susumu S. Kobayashi, Susumu S. Kobayashi, João Agostinho Machado-Neto, Eduardo Magalhães Rego, Eduardo Magalhães Rego, Robert Samuel Welner, Lorena Lobo de Figueiredo-Pontes, Lorena Lobo de Figueiredo-Pontes

    Diterbitkan 2022-09-01
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  13. 13
    The Impact of On-Target Resistance Mediated by EGFR-T790M or EGFR-C797S on EGFR Exon 20 Insertion Mutation Active Tyrosine Kinase Inhibitors

    The Impact of On-Target Resistance Mediated by EGFR-T790M or EGFR-C797S on EGFR Exon 20 Insertion Mutation Active Tyrosine Kinase Inhibitors oleh Ikei S. Kobayashi, MD, PhD, William Shaffer, MS, Hollis Viray, MD, Deepa Rangachari, MD, Paul A. VanderLaan, MD, PhD, Susumu S. Kobayashi, MD, PhD, Daniel B. Costa, MD, PhD

    Diterbitkan 2024-01-01
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  14. 14
    NAD Modulates DNA Methylation and Cell Differentiation

    NAD Modulates DNA Methylation and Cell Differentiation oleh Simone Ummarino, Clinton Hausman, Giulia Gaggi, Lucrezia Rinaldi, Mahmoud A. Bassal, Yanzhou Zhang, Andy Joe Seelam, Ikei S. Kobayashi, Marta Borchiellini, Alexander K. Ebralidze, Barbara Ghinassi, Bon Q. Trinh, Susumu S. Kobayashi, Annalisa Di Ruscio

    Diterbitkan 2021-11-01
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  15. 15
    LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion

    LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion oleh Shunta Mori, Hiroki Izumi, Mitsugu Araki, Jie Liu, Yu Tanaka, Yosuke Kagawa, Yukari Sagae, Biao Ma, Yuta Isaka, Yoko Sasakura, Shogo Kumagai, Yuta Sakae, Kosuke Tanaka, Yuji Shibata, Hibiki Udagawa, Shingo Matsumoto, Kiyotaka Yoh, Yasushi Okuno, Koichi Goto, Susumu S. Kobayashi

    Diterbitkan 2024-04-01
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  16. 16
    The EGFR C797S Mutation Confers Resistance to a Novel EGFR Inhibitor CLN-081 to EGFR Exon 20 Insertion Mutations

    The EGFR C797S Mutation Confers Resistance to a Novel EGFR Inhibitor CLN-081 to EGFR Exon 20 Insertion Mutations oleh Yosuke Kagawa, MD, Takuma Hayashida, MS, Jie Liu, BS, Shunta Mori, MD, Hiroki Izumi, MD, PhD, Shogo Kumagai, MD, PhD, Hibiki Udagawa, MD, PhD, Noboru Hattori, MD, PhD, Koichi Goto, MD, PhD, Susumu S. Kobayashi, MD, PhD

    Diterbitkan 2023-03-01
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  17. 17
    EGFR-A763_Y764insFQEA Is a Unique Exon 20 Insertion Mutation That Displays Sensitivity to Approved and In-Development Lung Cancer EGFR Tyrosine Kinase Inhibitors

    EGFR-A763_Y764insFQEA Is a Unique Exon 20 Insertion Mutation That Displays Sensitivity to Approved and In-Development Lung Cancer EGFR Tyrosine Kinase Inhibitors oleh Pedro E.N.S. Vasconcelos, MS, Carol Gergis, MS, Hollis Viray, MD, Andreas Varkaris, MD, PhD, Masanori Fujii, MD, PhD, Deepa Rangachari, MD, Paul A. VanderLaan, MD, PhD, Ikei S. Kobayashi, MD, PhD, Susumu S. Kobayashi, MD, PhD, Daniel B. Costa, MD, PhD

    Diterbitkan 2020-09-01
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