Hasil Pencarian - Srinivasaraghavan Kannan

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  1. 1
    Role of tryptophan side chain dynamics on the Trp-cage mini-protein folding studied by molecular dynamics simulations.

    Role of tryptophan side chain dynamics on the Trp-cage mini-protein folding studied by molecular dynamics simulations. oleh Srinivasaraghavan Kannan, Martin Zacharias

    Diterbitkan 2014-01-01
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  2. 2
    Folding of Trp-cage Mini Protein Using Temperature and Biasing Potential Replica—Exchange Molecular Dynamics Simulations

    Folding of Trp-cage Mini Protein Using Temperature and Biasing Potential Replica—Exchange Molecular Dynamics Simulations oleh Srinivasaraghavan Kannan, Martin Zacharias

    Diterbitkan 2009-03-01
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  3. 3
    The polybasic insert, the RBD of the SARS-CoV-2 spike protein, and the feline coronavirus – evolved or yet to evolve

    The polybasic insert, the RBD of the SARS-CoV-2 spike protein, and the feline coronavirus – evolved or yet to evolve oleh Anshul Budhraja, Sakshi Pandey, Srinivasaraghavan Kannan, Chandra S. Verma, Prasanna Venkatraman

    Diterbitkan 2021-03-01
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  4. 4
    Inhibiting S100B(ββ) for Activating Wild-Type p53: Design of Stapled Peptides

    Inhibiting S100B(ββ) for Activating Wild-Type p53: Design of Stapled Peptides oleh Srinivasaraghavan Kannan, Pietro G. A. Aronica, Yaw Sing Tan, Chandra S. Verma

    Diterbitkan 2019-03-01
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  5. 5
    JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1

    JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1 oleh Bahareh Tabanifar, Anbalagan Moorthy, Heng Hang Tsai, Srinivasaraghavan Kannan, Chandra S. Verma, Kanaga Sabapathy

    Diterbitkan 2023-09-01
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  6. 6
    Computational Design of Macrocyclic Binders of S100B(ββ): Novel Peptide Theranostics

    Computational Design of Macrocyclic Binders of S100B(ββ): Novel Peptide Theranostics oleh Srinivasaraghavan Kannan, Pietro G. A. Aronica, Thanh Binh Nguyen, Jianguo Li, Chandra S. Verma

    Diterbitkan 2021-01-01
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  7. 7
    Disrupting the Dok3–Card9 Interaction with Synthetic Peptides Enhances Antifungal Effector Functions of Human Neutrophils

    Disrupting the Dok3–Card9 Interaction with Synthetic Peptides Enhances Antifungal Effector Functions of Human Neutrophils oleh Jia Tong Loh, Joey Kay Hui Teo, Srinivasaraghavan Kannan, Chandra S. Verma, Hong-Hwa Lim, Kong-Peng Lam

    Diterbitkan 2023-06-01
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  8. 8
    Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib

    Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib oleh Srinivasaraghavan Kannan, Mohan R. Pradhan, Garima Tiwari, Wei-Chong Tan, Balram Chowbay, Eng Huat Tan, Daniel Shao-Weng Tan, Chandra Verma

    Diterbitkan 2017-05-01
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  9. 9
    Src activates retrograde membrane traffic through phosphorylation of GBF1

    Src activates retrograde membrane traffic through phosphorylation of GBF1 oleh Joanne Chia, Shyi-Chyi Wang, Sheena Wee, David James Gill, Felicia Tay, Srinivasaraghavan Kannan, Chandra S Verma, Jayantha Gunaratne, Frederic A Bard

    Diterbitkan 2021-12-01
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  10. 10
    Expanding the DNA editing toolbox: Novel lambda integrase variants targeting microalgal and human genome sequences

    Expanding the DNA editing toolbox: Novel lambda integrase variants targeting microalgal and human genome sequences oleh Jia Wei Siau, Asim Azhar Siddiqui, Sze Yi Lau, Srinivasaraghavan Kannan, Sabrina Peter, Yingying Zeng, Chandra Verma, Peter Droge, John F. Ghadessy

    Diterbitkan 2024-01-01
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  11. 11
    Small Molecules Targeting the Inactive Form of the Mnk1/2 Kinases

    Small Molecules Targeting the Inactive Form of the Mnk1/2 Kinases oleh Srinivasaraghavan Kannan, Mohan R. Pradhan, Joseph Cherian, Thomas L. Joseph, Zhi Ying Poh, Yang Hai Yan, Ho Melvyn, Liu Boping, Hill Jeffrey, Kassoum Nacro, Chandra S. Verma

    Diterbitkan 2017-11-01
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  12. 12
    A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

    A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing oleh Conrad V. Simoben, Dina Robaa, Alokta Chakrabarti, Karin Schmidtkunz, Martin Marek, Julien Lancelot, Srinivasaraghavan Kannan, Jelena Melesina, Tajith B. Shaik, Raymond J. Pierce, Christophe Romier, Manfred Jung, Wolfgang Sippl

    Diterbitkan 2018-03-01
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  13. 13
    Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni.

    Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni. oleh Martin Marek, Srinivasaraghavan Kannan, Alexander-Thomas Hauser, Marina Moraes Mourão, Stéphanie Caby, Vincent Cura, Diana A Stolfa, Karin Schmidtkunz, Julien Lancelot, Luiza Andrade, Jean-Paul Renaud, Guilherme Oliveira, Wolfgang Sippl, Manfred Jung, Jean Cavarelli, Raymond J Pierce, Christophe Romier

    Diterbitkan 2013-01-01
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  14. 14
    A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays

    A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays oleh Stephen H. Kasper, Stephanie Otten, Brian Squadroni, Cionna Orr‐Terry, Yi Kuang, Lily Mussallem, Lan Ge, Lin Yan, Srinivasaraghavan Kannan, Chandra S. Verma, Christopher J. Brown, Charles W. Johannes, David P. Lane, Arun Chandramohan, Anthony W. Partridge, Lee R. Roberts, Hubert Josien, Alex G. Therien, Erik C. Hett, Bonnie J. Howell, Andrea Peier, Xi Ai, Jason Cassaday

    Diterbitkan 2023-09-01
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  15. 15
    Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties

    Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties oleh Anthony W. Partridge, Hung Yi Kristal Kaan, Yu-Chi Juang, Ahmad Sadruddin, Shuhui Lim, Christopher J. Brown, Simon Ng, Dawn Thean, Fernando Ferrer, Charles Johannes, Tsz Ying Yuen, Srinivasaraghavan Kannan, Pietro Aronica, Yaw Sing Tan, Mohan R. Pradhan, Chandra S. Verma, Jerome Hochman, Shiying Chen, Hui Wan, Sookhee Ha, Brad Sherborne, David P. Lane, Tomi K. Sawyer

    Diterbitkan 2019-06-01
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  16. 16
    Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation

    Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation oleh Li Ren Kong, Richard Weijie Ong, Tuan Zea Tan, Nur Afiqah Binte Mohamed Salleh, Matan Thangavelu, Jane Vin Chan, Lie Yong Judice Koh, Giridharan Periyasamy, Jieying Amelia Lau, Thi Bich Uyen Le, Lingzhi Wang, Miyoung Lee, Srinivasaraghavan Kannan, Chandra S. Verma, Chwee Ming Lim, Wee Joo Chng, David P. Lane, Ashok Venkitaraman, Huynh The Hung, Chit Fang Cheok, Boon Cher Goh

    Diterbitkan 2020-04-01
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  17. 17
    PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression

    PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression oleh Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S. Verma, Yvonne Tay, Daniel Shao Weng Tan, Wai Leong Tam

    Diterbitkan 2024-07-01
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  18. 18
    Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists

    Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists oleh Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G. Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra S. Verma, David P. Lane, Tomi K. Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J. Brown, Charles W. Johannes, Anthony W. Partridge

    Diterbitkan 2024-01-01
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  19. 19
    A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma

    A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma oleh Li Ren Kong, Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Tuan Zea Tan, Nicholas L. Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel S. W. Tan, N. Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S. Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline S. J. Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H. Phillip Koeffler, Soo Chin Lee, Dennis Kappei, Huynh The Hung, Boon Cher Goh

    Diterbitkan 2020-03-01
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  20. 20
    Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities

    Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities oleh Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Lum, Wai Kit Cheong, Khay Guan Yeoh, Ker Kan Tan, Radoslaw M. Sobota, Chandra S. Verma, David P. Lane, Wai Leong Tam, Ashok R. Venkitaraman

    Diterbitkan 2023-03-01
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