Hasil Pencarian - Simon A. Cobbold

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  1. 1
    Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism.

    Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism. oleh Ian A Lewis, Mark Wacker, Kellen L Olszewski, Simon A Cobbold, Katelynn S Baska, Asako Tan, Michael T Ferdig, Manuel Llinás

    Diterbitkan 2014-01-01
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  2. 2
    Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum.

    Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum. oleh Jessica K O'Hara, Lewis J Kerwin, Simon A Cobbold, Jonathan Tai, Thomas A Bedell, Paul J Reider, Manuel Llinás

    Diterbitkan 2014-01-01
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  3. 3
    The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens.

    The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens. oleh Sanduni V Hapuarachchi, Simon A Cobbold, Sarah H Shafik, Adelaide S M Dennis, Malcolm J McConville, Rowena E Martin, Kiaran Kirk, Adele M Lehane

    Diterbitkan 2017-02-01
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  4. 4
    Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking.

    Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking. oleh Kit Kennedy, Simon A Cobbold, Eric Hanssen, Jakob Birnbaum, Natalie J Spillman, Emma McHugh, Hannah Brown, Leann Tilley, Tobias Spielmann, Malcolm J McConville, Stuart A Ralph

    Diterbitkan 2019-07-01
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  5. 5
    Non‐canonical metabolic pathways in the malaria parasite detected by isotope‐tracing metabolomics

    Non‐canonical metabolic pathways in the malaria parasite detected by isotope‐tracing metabolomics oleh Simon A Cobbold, Madel V Tutor, Philip Frasse, Emma McHugh, Markus Karnthaler, Darren J Creek, Audrey Odom John, Leann Tilley, Stuart A Ralph, Malcolm J McConville

    Diterbitkan 2021-04-01
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  6. 6
    The natural function of the malaria parasite’s chloroquine resistance transporter

    The natural function of the malaria parasite’s chloroquine resistance transporter oleh Sarah H. Shafik, Simon A. Cobbold, Kawthar Barkat, Sashika N. Richards, Nicole S. Lancaster, Manuel Llinás, Simon J. Hogg, Robert L. Summers, Malcolm J. McConville, Rowena E. Martin

    Diterbitkan 2020-08-01
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  7. 7
    The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in <named-content content-type="genus-species">Plasmodium falciparum</named-content>

    The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in <named-content content-type="genus-species">Plasmodium... oleh Laure Dumont, Mark B. Richardson, Phillip van der Peet, Danushka S. Marapana, Tony Triglia, Matthew W. A. Dixon, Alan F. Cowman, Spencer J. Williams, Leann Tilley, Malcolm J. McConville, Simon A. Cobbold

    Diterbitkan 2019-12-01
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  8. 8
    Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

    Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome oleh Jessica L. Bridgford, Stanley C. Xie, Simon A. Cobbold, Charisse Flerida A. Pasaje, Susann Herrmann, Tuo Yang, David L. Gillett, Lawrence R. Dick, Stuart A. Ralph, Con Dogovski, Natalie J. Spillman, Leann Tilley

    Diterbitkan 2018-09-01
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  9. 9
    Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance

    Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance oleh Tuo Yang, Lee M. Yeoh, Madel V. Tutor, Matthew W. Dixon, Paul J. McMillan, Stanley C. Xie, Jessica L. Bridgford, David L. Gillett, Michael F. Duffy, Stuart A. Ralph, Malcolm J. McConville, Leann Tilley, Simon A. Cobbold

    Diterbitkan 2019-11-01
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  10. 10
    The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

    The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides oleh Gillian M. Fisher, Simon A. Cobbold, Andrew Jezewski, Emma F. Carpenter, Megan Arnold, Annie N. Cowell, Erick T. Tjhin, Kevin J. Saliba, Tina S. Skinner-Adams, Marcus C. S. Lee, Audrey Odom John, Elizabeth A. Winzeler, Malcolm J. McConville, Sally-Ann Poulsen, Katherine T. Andrews

    Diterbitkan 2020-12-01
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  11. 11
    Design and characterization of a heterobifunctional degrader of KEAP1

    Design and characterization of a heterobifunctional degrader of KEAP1 oleh Hao Chen, Nghi H. Nguyen, Charlene M. Magtoto, Simon A. Cobbold, Grace M. Bidgood, Lizeth G. Meza Guzman, Lachlan W. Richardson, Jason Corbin, Amanda E. Au, Bernhard C. Lechtenberg, Rebecca Feltham, Kate D. Sutherland, Christoph Grohmann, Sandra E. Nicholson, Brad E. Sleebs

    Diterbitkan 2023-02-01
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  12. 12
    The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen-encoding var genes.

    The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen-encoding var genes. oleh Gerry Q Tonkin-Hill, Leily Trianty, Rintis Noviyanti, Hanh H T Nguyen, Boni F Sebayang, Daniel A Lampah, Jutta Marfurt, Simon A Cobbold, Janavi S Rambhatla, Malcolm J McConville, Stephen J Rogerson, Graham V Brown, Karen P Day, Ric N Price, Nicholas M Anstey, Anthony T Papenfuss, Michael F Duffy

    Diterbitkan 2018-03-01
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  13. 13
    Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms

    Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms oleh Christoph Grohmann, Charlene M. Magtoto, Joel R. Walker, Ngee Kiat Chua, Anna Gabrielyan, Mary Hall, Simon A. Cobbold, Stephen Mieruszynski, Martin Brzozowski, Daniel S. Simpson, Hao Dong, Bridget Dorizzi, Annette V. Jacobsen, Emma Morrish, Natasha Silke, James M. Murphy, Joan K. Heath, Andrea Testa, Chiara Maniaci, Alessio Ciulli, Guillaume Lessene, John Silke, Rebecca Feltham

    Diterbitkan 2022-04-01
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  14. 14
    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death

    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death oleh Daniel Frank, Sarah E. Garnish, Jarrod J. Sandow, Ashley Weir, Lin Liu, Elise Clayer, Lizeth Meza, Maryam Rashidi, Simon A. Cobbold, Simon R. Scutts, Marcel Doerflinger, Holly Anderton, Kate E. Lawlor, Najoua Lalaoui, Andrew J. Kueh, Vik Ven Eng, Rebecca L. Ambrose, Marco J. Herold, Andre L. Samson, Rebecca Feltham, James M. Murphy, Gregor Ebert, Jaclyn S. Pearson, James E. Vince

    Diterbitkan 2022-07-01
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