Hasil Pencarian - Sarat Chandarlapaty

Perbaiki Hasil
  1. 1
    Pathologic complete response to KEYNOTE522 and HER2-directed therapy for synchronous TNBC and HER2+ breast cancer

    Pathologic complete response to KEYNOTE522 and HER2-directed therapy for synchronous TNBC and HER2+ breast cancer oleh Nicholas Mai, Jie-Fu Chen, Satshil Rana, Mark Robson, Sarat Chandarlapaty, Ezra Y. Rosen

    Diterbitkan 2024-07-01
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  2. 2
    Incidence of HER2-expressing brain metastases in patients with HER2-null breast cancer: a matched case analysis

    Incidence of HER2-expressing brain metastases in patients with HER2-null breast cancer: a matched case analysis oleh Nelson S. Moss, Jolene M. Singh, Anne S. Reiner, Joshua Z. Drago, Shanu Modi, Andrew D. Seidman, Sarat Chandarlapaty, Dara S. Ross

    Diterbitkan 2023-10-01
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  3. 3
    Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns

    Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns oleh Lidia Mateo, Miquel Duran-Frigola, Albert Gris-Oliver, Marta Palafox, Maurizio Scaltriti, Pedram Razavi, Sarat Chandarlapaty, Joaquin Arribas, Meritxell Bellet, Violeta Serra, Patrick Aloy

    Diterbitkan 2020-09-01
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  4. 4
    Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling.

    Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. oleh Qing-Bai She, Sarat Chandarlapaty, Qing Ye, Jose Lobo, Kathleen M Haskell, Karen R Leander, Deborah DeFeo-Jones, Hans E Huber, Neal Rosen

    Diterbitkan 2008-08-01
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  5. 5
    Reversible histone glycation is associated with disease-related changes in chromatin architecture

    Reversible histone glycation is associated with disease-related changes in chromatin architecture oleh Qingfei Zheng, Nathaniel D. Omans, Rachel Leicher, Adewola Osunsade, Albert S. Agustinus, Efrat Finkin-Groner, Hannah D’Ambrosio, Bo Liu, Sarat Chandarlapaty, Shixin Liu, Yael David

    Diterbitkan 2019-03-01
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  6. 6
    Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody

    Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody oleh Andres Lopez-Albaitero, Hong Xu, Hongfen Guo, Linlin Wang, Zhihao Wu, Hoa Tran, Sarat Chandarlapaty, Maurizio Scaltriti, Yelena Janjigian, Elisa de Stanchina, Nai-Kong V. Cheung

    Diterbitkan 2017-03-01
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  7. 7
    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer

    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer oleh Sungsoo Kim, Jessica Armand, Anton Safonov, Mimi Zhang, Rajesh K. Soni, Gary Schwartz, Julia E. McGuinness, Hanina Hibshoosh, Pedram Razavi, Minah Kim, Sarat Chandarlapaty, Hee Won Yang

    Diterbitkan 2023-11-01
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  8. 8
    Predictors of response to CDK4/6i retrial after prior CDK4/6i failure in ER+ metastatic breast cancer

    Predictors of response to CDK4/6i retrial after prior CDK4/6i failure in ER+ metastatic breast cancer oleh Nicholas Mai, Carlos H. dos Anjos, Pedram Razavi, Anton Safonov, Sujata Patil, Yuan Chen, Joshua Z. Drago, Shanu Modi, Jacqueline F. Bromberg, Chau T. Dang, Dazhi Liu, Larry Norton, Mark Robson, Sarat Chandarlapaty, Komal Jhaveri

    Diterbitkan 2024-10-01
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  9. 9
    A phase I trial of ganetespib in combination with paclitaxel and trastuzumab in patients with human epidermal growth factor receptor-2 (HER2)-positive metastatic breast cancer

    A phase I trial of ganetespib in combination with paclitaxel and trastuzumab in patients with human epidermal growth factor receptor-2 (HER2)-positive metastatic breast cancer oleh Komal Jhaveri, Rui Wang, Eleonora Teplinsky, Sarat Chandarlapaty, David Solit, Karen Cadoo, James Speyer, Gabriella D’Andrea, Sylvia Adams, Sujata Patil, Sofia Haque, Tara O’Neill, Kent Friedman, Francisco J. Esteva, Clifford Hudis, Shanu Modi

    Diterbitkan 2017-08-01
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  10. 10
    HER2 + breast cancers evade anti-HER2 therapy via a switch in driver pathway

    HER2 + breast cancers evade anti-HER2 therapy via a switch in driver pathway oleh Alison E. Smith, Emanuela Ferraro, Anton Safonov, Cristina Bernado Morales, Enrique J. Arenas Lahuerta, Qing Li, Amanda Kulick, Dara Ross, David B. Solit, Elisa de Stanchina, Jorge Reis-Filho, Neal Rosen, Joaquín Arribas, Pedram Razavi, Sarat Chandarlapaty

    Diterbitkan 2021-11-01
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  11. 11
    Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab

    Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab oleh Emanuela Ferraro, Jasmeet Singh, Sujata Patil, Pedram Razavi, Shanu Modi, Sarat Chandarlapaty, Andrea V. Barrio, Rachna Malani, Ingo K. Mellinghoff, Adrienne Boire, Hannah Y. Wen, Edi Brogi, Andrew D. Seidman, Larry Norton, Mark E. Robson, Chau T. Dang

    Diterbitkan 2022-03-01
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  12. 12
    Glucocorticoid receptor modulation decreases ER-positive breast cancer cell proliferation and suppresses wild-type and mutant ER chromatin association

    Glucocorticoid receptor modulation decreases ER-positive breast cancer cell proliferation and suppresses wild-type and mutant ER chromatin association oleh Eva Tonsing-Carter, Kyle M. Hernandez, Caroline R. Kim, Ryan V. Harkless, Alyce Oh, Kathleen R. Bowie, Diana C. West-Szymanski, Mayra A. Betancourt-Ponce, Bradley D. Green, Ricardo R. Lastra, Gini F. Fleming, Sarat Chandarlapaty, Suzanne D. Conzen

    Diterbitkan 2019-07-01
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  13. 13
    AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer

    AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer oleh Aditya Bardia, Sarat Chandarlapaty, Hannah M. Linden, Gary A. Ulaner, Alice Gosselin, Sylvaine Cartot-Cotton, Patrick Cohen, Séverine Doroumian, Gautier Paux, Marina Celanovic, Vasiliki Pelekanou, Jeffrey E. Ming, Nils Ternès, Monsif Bouaboula, Joon Sang Lee, Anne-Laure Bauchet, Mario Campone

    Diterbitkan 2022-07-01
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  14. 14
    Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

    Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation oleh Sean W Fanning, Christopher G Mayne, Venkatasubramanian Dharmarajan, Kathryn E Carlson, Teresa A Martin, Scott J Novick, Weiyi Toy, Bradley Green, Srinivas Panchamukhi, Benita S Katzenellenbogen, Emad Tajkhorshid, Patrick R Griffin, Yang Shen, Sarat Chandarlapaty, John A Katzenellenbogen, Geoffrey L Greene

    Diterbitkan 2016-02-01
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  15. 15
    Whole‐exome sequencing analysis of juvenile papillomatosis and coexisting breast carcinoma

    Whole‐exome sequencing analysis of juvenile papillomatosis and coexisting breast carcinoma oleh Timothy M D'Alfonso, Fresia Pareja, Arnaud Da Cruz Paula, Mahsa Vahdatinia, Andrea Gazzo, Lorenzo Ferrando, Edaise M da Silva, Esther Cheng, Lisa Sclafani, Sarat Chandarlapaty, Hong Zhang, Syed A Hoda, Hannah Y Wen, Edi Brogi, Britta Weigelt, Jorge S Reis‐Filho

    Diterbitkan 2021-03-01
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  16. 16
    TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer

    TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer oleh Edaise M. da Silva, Pier Selenica, Mahsa Vahdatinia, Fresia Pareja, Arnaud Da Cruz Paula, Lorenzo Ferrando, Andrea M. Gazzo, Higinio Dopeso, Dara S. Ross, Ariya Bakhteri, Nadeem Riaz, Sarat Chandarlapaty, Pedram Razavi, Larry Norton, Hannah Y. Wen, Edi Brogi, Britta Weigelt, Hong Zhang, Jorge S. Reis-Filho

    Diterbitkan 2021-04-01
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  17. 17
    Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer

    Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer oleh Megan L. Kruse, Mona Patel, Jeffrey McManus, Yoon-Mi Chung, Xiuxiu Li, Wei Wei, Peter S. Bazeley, Fumihiko Nakamura, Aimalie Hardaway, Erinn Downs, Sarat Chandarlapaty, Mathew Thomas, Halle C.F. Moore, George T. Budd, W.H. Wilson Tang, Stanley L. Hazen, Aaron Bernstein, Serena Nik-Zainal, Jame Abraham, Nima Sharifi

    Diterbitkan 2021-10-01
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  18. 18
    The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

    The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells oleh Sean W Fanning, Rinath Jeselsohn, Venkatasubramanian Dharmarajan, Christopher G Mayne, Mostafa Karimi, Gilles Buchwalter, René Houtman, Weiyi Toy, Colin E Fowler, Ross Han, Muriel Lainé, Kathryn E Carlson, Teresa A Martin, Jason Nowak, Jerome C Nwachukwu, David J Hosfield, Sarat Chandarlapaty, Emad Tajkhorshid, Kendall W Nettles, Patrick R Griffin, Yang Shen, John A Katzenellenbogen, Myles Brown, Geoffrey L Greene

    Diterbitkan 2018-11-01
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  19. 19
    ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance

    ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance oleh Antonio Strillacci, Pasquale Sansone, Vinagolu K. Rajasekhar, Mesruh Turkekul, Vitaly Boyko, Fanli Meng, Brian Houck-Loomis, David Brown, Michael F. Berger, Ronald C. Hendrickson, Qing Chang, Elisa de Stanchina, Fresia Pareja, Jorge S. Reis-Filho, Ramya Segu Rajappachetty, Isabella Del Priore, Bo Liu, Yanyan Cai, Alex Penson, Chiara Mastroleo, Marjan Berishaj, Francesca Borsetti, Enzo Spisni, David Lyden, Sarat Chandarlapaty, Jacqueline Bromberg

    Diterbitkan 2022-08-01
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  20. 20
    Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer

    Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer oleh Lillian M. Smyth, Gerald Batist, Funda Meric-Bernstam, Peter Kabos, Iben Spanggaard, Ana Lluch, Komal Jhaveri, Andrea Varga, Andrea Wong, Alison M. Schram, Helen Ambrose, T. Hedley Carr, Elza C. de Bruin, Carolina Salinas-Souza, Andrew Foxley, Joana Hauser, Justin P. O. Lindemann, Rhiannon Maudsley, Robert McEwen, Michele Moschetta, Myria Nikolaou, Gaia Schiavon, Pedram Razavi, Udai Banerji, José Baselga, David M. Hyman, Sarat Chandarlapaty

    Diterbitkan 2021-04-01
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