Hasil Pencarian - Sachel Mok

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  1. 1
    Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites.

    Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites. oleh Frances Rocamora, Lei Zhu, Kek Yee Liong, Arjen Dondorp, Olivo Miotto, Sachel Mok, Zbynek Bozdech

    Diterbitkan 2018-03-01
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  2. 2
    Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa

    Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa oleh Joan Simam, Martin Rono, Joyce Ngoi, Mary Nyonda, Sachel Mok, Kevin Marsh, Zbynek Bozdech, Margaret Mackinnon

    Diterbitkan 2018-05-01
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  3. 3
    Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates.

    Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates. oleh Margaret J Mackinnon, Jinguang Li, Sachel Mok, Moses M Kortok, Kevin Marsh, Peter R Preiser, Zbynek Bozdech

    Diterbitkan 2009-10-01
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  4. 4
    Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum.

    Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum. oleh Archna P Gupta, Wai Hoe Chin, Lei Zhu, Sachel Mok, Yen-Hoon Luah, Eng-How Lim, Zbynek Bozdech

    Diterbitkan 2013-02-01
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  5. 5
    Global Spread of Mutant PfCRT and Its Pleiotropic Impact on <named-content content-type="genus-species">Plasmodium falciparum</named-content> Multidrug Resistance and Fitness

    Global Spread of Mutant PfCRT and Its Pleiotropic Impact on <named-content content-type="genus-species">Plasmodium falciparum</named-content> Multidrug Resistance and Fitness oleh Satish K. Dhingra, Stanislaw J. Gabryszewski, Jennifer L. Small-Saunders, Tomas Yeo, Philipp P. Henrich, Sachel Mok, David A. Fidock

    Diterbitkan 2019-04-01
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  6. 6
    Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages.

    Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages. oleh John Okombo, Sachel Mok, Tarrick Qahash, Tomas Yeo, Jade Bath, Lindsey M Orchard, Edward Owens, Imhoi Koo, Istvan Albert, Manuel Llinás, David A Fidock

    Diterbitkan 2022-10-01
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  7. 7
    Integrated analysis of the Plasmodium species transcriptome

    Integrated analysis of the Plasmodium species transcriptome oleh Regina Hoo, Lei Zhu, Anburaj Amaladoss, Sachel Mok, Onguma Natalang, Stacey A. Lapp, Guangan Hu, Kingsley Liew, Mary R. Galinski, Zbynek Bozdech, Peter R. Preiser

    Diterbitkan 2016-05-01
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  8. 8
    Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum.

    Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmo... oleh Michal Kucharski, Grennady Wirjanata, Sourav Nayak, Josephine Boentoro, Jerzy Michal Dziekan, Christina Assisi, Rob W van der Pluijm, Olivo Miotto, Sachel Mok, Arjen M Dondorp, Zbynek Bozdech

    Diterbitkan 2023-01-01
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  9. 9
    Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

    Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine oleh Leila S. Ross, Satish K. Dhingra, Sachel Mok, Tomas Yeo, Kathryn J. Wicht, Krittikorn Kümpornsin, Shannon Takala-Harrison, Benoit Witkowski, Rick M. Fairhurst, Frederic Ariey, Didier Menard, David A. Fidock

    Diterbitkan 2018-08-01
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  10. 10
    Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival

    Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival oleh Sachel Mok, Barbara H. Stokes, Nina F. Gnädig, Leila S. Ross, Tomas Yeo, Chanaki Amaratunga, Erik Allman, Lev Solyakov, Andrew R. Bottrill, Jaishree Tripathi, Rick M. Fairhurst, Manuel Llinás, Zbynek Bozdech, Andrew B. Tobin, David A. Fidock

    Diterbitkan 2021-01-01
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  11. 11
    Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13.

    Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13. oleh Nina F Gnädig, Barbara H Stokes, Rachel L Edwards, Gavreel F Kalantarov, Kim C Heimsch, Michal Kuderjavy, Audrey Crane, Marcus C S Lee, Judith Straimer, Katja Becker, Ilya N Trakht, Audrey R Odom John, Sachel Mok, David A Fidock

    Diterbitkan 2020-04-01
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  12. 12
    The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background

    The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background oleh Lei Zhu, Jaishree Tripathi, Frances Maureen Rocamora, Olivo Miotto, Rob van der Pluijm, Till S. Voss, Sachel Mok, Dominic P. Kwiatkowski, François Nosten, Nicholas P. J. Day, Nicholas J. White, Arjen M. Dondorp, Zbynek Bozdech, Tracking Resistance to Artemisinin Collaboration I

    Diterbitkan 2018-12-01
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  13. 13
    A Variant PfCRT Isoform Can Contribute to <italic toggle="yes">Plasmodium falciparum</italic> Resistance to the First-Line Partner Drug Piperaquine

    A Variant PfCRT Isoform Can Contribute to <italic toggle="yes">Plasmodium falciparum</italic> Resistance to the First-Line Partner Drug Piperaquine oleh Satish K. Dhingra, Devasha Redhi, Jill M. Combrinck, Tomas Yeo, John Okombo, Philipp P. Henrich, Annie N. Cowell, Purva Gupta, Matthew L. Stegman, Jonathan M. Hoke, Roland A. Cooper, Elizabeth Winzeler, Sachel Mok, Timothy J. Egan, David A. Fidock

    Diterbitkan 2017-07-01
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  14. 14
    Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance.

    Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance. oleh Con Dogovski, Stanley C Xie, Gaetan Burgio, Jess Bridgford, Sachel Mok, James M McCaw, Kesinee Chotivanich, Shannon Kenny, Nina Gnädig, Judith Straimer, Zbynek Bozdech, David A Fidock, Julie A Simpson, Arjen M Dondorp, Simon Foote, Nectarios Klonis, Leann Tilley

    Diterbitkan 2015-04-01
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  15. 15
    Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

    Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance oleh Luana C Mathieu, Horace Cox, Angela M Early, Sachel Mok, Yassamine Lazrek, Jeanne-Celeste Paquet, Maria-Paz Ade, Naomi W Lucchi, Quacy Grant, Venkatachalam Udhayakumar, Jean SF Alexandre, Magalie Demar, Pascal Ringwald, Daniel E Neafsey, David A Fidock, Lise Musset

    Diterbitkan 2020-05-01
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  16. 16
    Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum

    Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum oleh Krittikorn Kümpornsin, Theerarat Kochakarn, Tomas Yeo, John Okombo, Madeline R. Luth, Johanna Hoshizaki, Mukul Rawat, Richard D. Pearson, Kyra A. Schindler, Sachel Mok, Heekuk Park, Anne-Catrin Uhlemann, Gouranga P. Jana, Bikash C. Maity, Benoît Laleu, Elodie Chenu, James Duffy, Sonia Moliner Cubel, Virginia Franco, Maria G. Gomez-Lorenzo, Francisco Javier Gamo, Elizabeth A. Winzeler, David A. Fidock, Thanat Chookajorn, Marcus C. S. Lee

    Diterbitkan 2023-05-01
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  17. 17
    Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites

    Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites oleh Dorjbal Dorjsuren, Richard T. Eastman, Kathryn J. Wicht, Daniel Jansen, Daniel C. Talley, Benjamin A. Sigmon, Alexey V. Zakharov, Norma Roncal, Andrew T. Girvin, Yevgeniya Antonova-Koch, Paul M. Will, Pranav Shah, Hongmao Sun, Carleen Klumpp-Thomas, Sachel Mok, Tomas Yeo, Stephan Meister, Juan Jose Marugan, Leila S. Ross, Xin Xu, David J. Maloney, Ajit Jadhav, Bryan T. Mott, Richard J. Sciotti, Elizabeth A. Winzeler, Norman C. Waters, Robert F. Campbell, Wenwei Huang, Anton Simeonov, David A. Fidock

    Diterbitkan 2021-01-01
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  18. 18
    Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

    Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness oleh Barbara H Stokes, Satish K Dhingra, Kelly Rubiano, Sachel Mok, Judith Straimer, Nina F Gnädig, Ioanna Deni, Kyra A Schindler, Jade R Bath, Kurt E Ward, Josefine Striepen, Tomas Yeo, Leila S Ross, Eric Legrand, Frédéric Ariey, Clark H Cunningham, Issa M Souleymane, Adama Gansané, Romaric Nzoumbou-Boko, Claudette Ndayikunda, Abdunoor M Kabanywanyi, Aline Uwimana, Samuel J Smith, Olimatou Kolley, Mathieu Ndounga, Marian Warsame, Rithea Leang, François Nosten, Timothy JC Anderson, Philip J Rosenthal, Didier Ménard, David A Fidock

    Diterbitkan 2021-07-01
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  19. 19
    Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

    Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation oleh Selina Bopp, Charisse Flerida A. Pasaje, Robert L. Summers, Pamela Magistrado-Coxen, Kyra A. Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S. Nasamu, Allison R. Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M. Early, Amanda K. Lukens, Danny Milner, Jeremy Furtado, Francisco-Javier Gamo, Elizabeth A. Winzeler, Sarah K. Volkman, Maëlle Duffey, Benoît Laleu, David A. Fidock, Susan Wyllie, Jacquin C. Niles, Dyann F. Wirth

    Diterbitkan 2023-03-01
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