Hasil Pencarian - S.G. Younkin

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  1. 1
    Alterations in Cerebral Blood Flow and Glucose Utilization in Mice Overexpressing the Amyloid Precursor Protein

    Alterations in Cerebral Blood Flow and Glucose Utilization in Mice Overexpressing the Amyloid Precursor Protein oleh Kiyoshi Niwa, Ken Kazama, Steven G. Younkin, George A. Carlson, Costantino Iadecola

    Diterbitkan 2002-02-01
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  2. 2
    Co-expression of β-amyloid precursor protein (βAPP) and apolipoprotein E in cell culture: analysis of βAPP processing

    Co-expression of β-amyloid precursor protein (βAPP) and apolipoprotein E in cell culture: analysis of βAPP processing oleh Anja Leona Biere, Beth Ostaszewski, Hongwei Zhao, Susan Gillespie, Steven G. Younkin, Dennis J. Selkoe

    Diterbitkan 1995-06-01
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  3. 3
    On multi-marker tests for association in case-control studies

    On multi-marker tests for association in case-control studies oleh Margaret A Taub, Holger R Schwender, Samuel G Younkin, Thomas A Louis, Ingo eRuczinski

    Diterbitkan 2013-12-01
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  4. 4
    Multiple insulin degrading enzyme variants alter in vitro reporter gene expression.

    Multiple insulin degrading enzyme variants alter in vitro reporter gene expression. oleh Olivia Belbin, Olivia Belbin, Michael Crump, Gina D Bisceglio, Minerva M Carrasquillo, Kevin Morgan, Steven G Younkin

    Diterbitkan 2011-01-01
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  5. 5
    Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study.

    Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study. oleh Jeannette Simino, Zhiying Wang, Jan Bressler, Vincent Chouraki, Qiong Yang, Steven G Younkin, Sudha Seshadri, Myriam Fornage, Eric Boerwinkle, Thomas H Mosley

    Diterbitkan 2017-01-01
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  6. 6
    Cholesterol-Dependent γ-Secretase Activity in Buoyant Cholesterol-Rich Membrane Microdomains

    Cholesterol-Dependent γ-Secretase Activity in Buoyant Cholesterol-Rich Membrane Microdomains oleh Suzanne Wahrle, Pritam Das, Andrew C. Nyborg, Chris McLendon, Mikio Shoji, Takeshi Kawarabayashi, Linda H. Younkin, Steven G. Younkin, Todd E. Golde

    Diterbitkan 2002-02-01
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  7. 7
    Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-Protein

    Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-Protein oleh Martin Citron, Christopher B. Eckman, Thekla S. Diehl, Chris Corcoran, Beth L. Ostaszewski, Weiming Xia, Georges Levesque, Peter St. George Hyslop, Steven G. Younkin, Dennis J. Selkoe

    Diterbitkan 1998-08-01
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  8. 8
    Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease.

    Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease. oleh Joanna L Jankowsky, Hilda H Slunt, Victoria Gonzales, Alena V Savonenko, Jason C Wen, Nancy A Jenkins, Neal G Copeland, Linda H Younkin, Henry A Lester, Steven G Younkin, David R Borchelt

    Diterbitkan 2005-12-01
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  9. 9
    A Presenilin 1 Mutation Associated with Familial Frontotemporal Dementia Inhibits γ-Secretase Cleavage of APP and Notch

    A Presenilin 1 Mutation Associated with Familial Frontotemporal Dementia Inhibits γ-Secretase Cleavage of APP and Notch oleh Zareen Amtul, Patrick A. Lewis, Sian Piper, Richard Crook, Matt Baker, Kirk Findlay, Andrew Singleton, Marion Hogg, Linda Younkin, Steven G. Younkin, John Hardy, Michael Hutton, Bradley F. Boeve, David Tang-Wai, Todd E. Golde

    Diterbitkan 2002-03-01
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  10. 10
    Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies.

    Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies. oleh Daniel P Wickland, Yingxue Ren, Jason P Sinnwell, Joseph S Reddy, Cyril Pottier, Vivekananda Sarangi, Minerva M Carrasquillo, Owen A Ross, Steven G Younkin, Nilüfer Ertekin-Taner, Rosa Rademakers, Matthew E Hudson, Liudmila Sergeevna Mainzer, Joanna M Biernacka, Yan W Asmann

    Diterbitkan 2021-01-01
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  11. 11
    Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology.

    Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology. oleh Fanggeng Zou, Olivia Belbin, Olivia Belbin, Minerva M Carrasquillo, Oliver J Culley, Talisha A Hunter, Li Ma, Gina D Bisceglio, Mariet Allen, Dennis W Dickson, Neill R Graff-Radford, Ronald C Petersen, Genetic and Environmental Risk for Alzheimer’s disease (GERAD1) Consortium, Kevin Morgan, Steven G Younkin

    Diterbitkan 2013-01-01
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  12. 12
    Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

    Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight oleh Mark T. W. Ebbert, Tanner D. Jensen, Karen Jansen-West, Jonathon P. Sens, Joseph S. Reddy, Perry G. Ridge, John S. K. Kauwe, Veronique Belzil, Luc Pregent, Minerva M. Carrasquillo, Dirk Keene, Eric Larson, Paul Crane, Yan W. Asmann, Nilufer Ertekin-Taner, Steven G. Younkin, Owen A. Ross, Rosa Rademakers, Leonard Petrucelli, John D. Fryer

    Diterbitkan 2019-05-01
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  13. 13
    Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease.

    Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease. oleh Minerva M Carrasquillo, Olivia Belbin, Olivia Belbin, Fanggeng Zou, Mariet Allen, Nilufer Ertekin-Taner, Morad Ansari, Samantha L Wilcox, Mariah R Kashino, Li Ma, Linda H Younkin, Samuel G Younkin, Curtis S Younkin, Toros A Dincman, Melissa E Howard, Chanley C Howell, Chloe M Stanton, Christopher M Watson, Michael Crump, Veronique Vitart, Caroline Hayward, Nicholas D Hastie, Igor Rudan, Harry Campbell, Ozren Polasek, Kristelle Brown, Peter Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Patrick G Kehoe, David M Mann, A David Smith, Helen Beaumont, Donald Warden, Clive Holmes, Reinhard Heun, Heike Kölsch, Noor Kalsheker, V Shane Pankratz, Dennis W Dickson, Neill R Graff-Radford, Ronald C Petersen, Alan F Wright, Steven G Younkin, Kevin Morgan

    Diterbitkan 2010-01-01
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  14. 14
    Alzheimer’s disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions

    Alzheimer’s disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions oleh Xue Wang, Mariet Allen, Özkan İş, Joseph S. Reddy, Frederick Q. Tutor-New, Monica Castanedes Casey, Minerva M. Carrasquillo, Stephanie R. Oatman, Yuhao Min, Yan W. Asmann, Cory Funk, Thuy Nguyen, Charlotte C.G. Ho, Kimberly G. Malphrus, Nicholas T. Seyfried, Allan I. Levey, Steven G. Younkin, Melissa E. Murray, Dennis W. Dickson, Nathan D. Price, Todd E. Golde, Nilüfer Ertekin-Taner

    Diterbitkan 2022-01-01
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  15. 15
    APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

    APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids oleh Jing Zhao, Yuan Fu, Yu Yamazaki, Yingxue Ren, Mary D. Davis, Chia-Chen Liu, Wenyan Lu, Xue Wang, Kai Chen, Yesesri Cherukuri, Lin Jia, Yuka A. Martens, Lucy Job, Francis Shue, Thanh Thanh Nguyen, Steven G. Younkin, Neill R. Graff-Radford, Zbigniew K. Wszolek, David A. Brafman, Yan W. Asmann, Nilüfer Ertekin-Taner, Takahisa Kanekiyo, Guojun Bu

    Diterbitkan 2020-11-01
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  16. 16
    Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

    Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids oleh Jing Zhao, Yuan Fu, Yu Yamazaki, Yingxue Ren, Mary D. Davis, Chia-Chen Liu, Wenyan Lu, Xue Wang, Kai Chen, Yesesri Cherukuri, Lin Jia, Yuka A. Martens, Lucy Job, Francis Shue, Thanh Thanh Nguyen, Steven G. Younkin, Neill R. Graff-Radford, Zbigniew K. Wszolek, David A. Brafman, Yan W. Asmann, Nilüfer Ertekin-Taner, Takahisa Kanekiyo, Guojun Bu

    Diterbitkan 2021-05-01
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  17. 17
    Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer’s disease

    Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer’s disease oleh Jaeyoon Chung, Xiaoling Zhang, Mariet Allen, Xue Wang, Yiyi Ma, Gary Beecham, Thomas J. Montine, Steven G. Younkin, Dennis W. Dickson, Todd E. Golde, Nathan D. Price, Nilüfer Ertekin-Taner, Kathryn L. Lunetta, Jesse Mez, Alzheimer’s Disease Genetics Consortium, Richard Mayeux, Jonathan L. Haines, Margaret A. Pericak-Vance, Gerard Schellenberg, Gyungah R. Jun, Lindsay A. Farrer

    Diterbitkan 2018-02-01
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  18. 18
    LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD).

    LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD). oleh Sarah Lincoln, Mariet Allen, Claire L Cox, Louise P Walker, Kimberly Malphrus, Yushi Qiu, Thuy Nguyen, Christopher Rowley, Naomi Kouri, Julia Crook, V Shane Pankratz, Samuel Younkin, Linda Younkin, Minerva Carrasquillo, Fanggeng Zou, Samer O Abdul-Hay, Wolfdieter Springer, Sigrid B Sando, Jan O Aasly, Maria Barcikowska, Zbigniew K Wszolek, Jada M Lewis, Dennis Dickson, Neill R Graff-Radford, Ronald C Petersen, Elizabeth Eckman, Steven G Younkin, Nilüfer Ertekin-Taner

    Diterbitkan 2013-01-01
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  19. 19
    Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

    Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience oleh Perry G. Ridge, Celeste M. Karch, Simon Hsu, Ivan Arano, Craig C. Teerlink, Mark T. W. Ebbert, Josue D. Gonzalez Murcia, James M. Farnham, Anna R. Damato, Mariet Allen, Xue Wang, Oscar Harari, Victoria M. Fernandez, Rita Guerreiro, Jose Bras, John Hardy, Ronald Munger, Maria Norton, Celeste Sassi, Andrew Singleton, Steven G. Younkin, Dennis W. Dickson, Todd E. Golde, Nathan D. Price, Nilüfer Ertekin-Taner, Carlos Cruchaga, Alison M. Goate, Christopher Corcoran, JoAnn Tschanz, Lisa A. Cannon-Albright, John S. K. Kauwe, for the Alzheimer’s Disease Neuroimaging Initiative

    Diterbitkan 2018-01-01
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  20. 20
    Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

    Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience oleh Perry G. Ridge, Celeste M. Karch, Simon Hsu, Ivan Arano, Craig C. Teerlink, Mark T. W. Ebbert, Josue D. Gonzalez Murcia, James M. Farnham, Anna R. Damato, Mariet Allen, Xue Wang, Oscar Harari, Victoria M. Fernandez, Rita Guerreiro, Jose Bras, John Hardy, Ronald Munger, Maria Norton, Celeste Sassi, Andrew Singleton, Steven G. Younkin, Dennis W. Dickson, Todd E. Golde, Nathan D. Price, Nilüfer Ertekin-Taner, Carlos Cruchaga, Alison M. Goate, Christopher Corcoran, JoAnn Tschanz, Lisa A. Cannon-Albright, John S. K. Kauwe, for the Alzheimer’s Disease Neuroimaging Initiative

    Diterbitkan 2017-11-01
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