112 Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy oleh Kevin Schifferli, Gordon Moody, Karma Dacosta, Nina Chu, Ryan Gilbreth, Lori Clarke, Christina Gesse, Letizia Giardino, Cui Chen, Erin Sult, Noel Monks, Ravinder Tammali, Jon Chesebrough, Jessica Tong, Xiao-Tao Yao, Kapil Vashisht