Hasil Pencarian - Rodrigo Cristofoletti

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  1. 1
    A quantitative systems pharmacology (QSP) platform for preclinical to clinical translation of in-vivo CRISPR-Cas therapy

    A quantitative systems pharmacology (QSP) platform for preclinical to clinical translation of in-vivo CRISPR-Cas therapy oleh Devam A. Desai, Stephan Schmidt, Rodrigo Cristofoletti

    Diterbitkan 2024-09-01
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  2. 2
    Editorial: Insights in drug metabolism and transport: 2021

    Editorial: Insights in drug metabolism and transport: 2021 oleh Janny Piñeiro-Llanes, David E. Stec, Rodrigo Cristofoletti

    Diterbitkan 2023-05-01
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  3. 3
    Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Predict the Impact of CYP2C9 Genetic Polymorphisms, Co-Medication and Formulation on the Pharmacokinetics and Pharmacodynamics of Flurbiprofen

    Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Predict the Impact of CYP2C9 Genetic Polymorphisms, Co-Medication and Formulation on the Pharmacokinetics and Phar... oleh Ioannis Loisios-Konstantinidis, Rodrigo Cristofoletti, Masoud Jamei, David Turner, Jennifer Dressman

    Diterbitkan 2020-11-01
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  4. 4
    Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine’s Nonlinear Pharmacokinetics and Its Induction Potential on Cytochrome P450 3A4 and Cytochrome P450 2C9 Enzymes

    Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine’s Nonlinear Pharmacokinetics and Its Induction Potential on Cytochrome P450 3A4 and Cytochrome P4... oleh Xuefen Yin, Brian Cicali, Leyanis Rodriguez-Vera, Viera Lukacova, Rodrigo Cristofoletti, Stephan Schmidt

    Diterbitkan 2024-05-01
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  5. 5
    Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola<sup>®</sup> on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b)

    Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola<sup>®</sup> on the Luminal and Systemic Behavior of Loratadin... oleh Bart Hens, Marival Bermejo, Patrick Augustijns, Rodrigo Cristofoletti, Gregory E. Amidon, Gordon L. Amidon

    Diterbitkan 2020-06-01
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  6. 6
    Pharmacometrics, Physiologically Based Pharmacokinetics, Quantitative Systems Pharmacology—What's Next?—Joining Mechanistic and Epidemiological Approaches

    Pharmacometrics, Physiologically Based Pharmacokinetics, Quantitative Systems Pharmacology—What's Next?—Joining Mechanistic and Epidemiological Approaches oleh Stephan Schmidt, Sarah Kim, Valvanera Vozmediano, Rodrigo Cristofoletti, Almut G. Winterstein, Joshua D. Brown

    Diterbitkan 2019-06-01
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  7. 7
    Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug–Drug Interactions of Phenytoin

    Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug–Drug Interactions of Phenytoin oleh Leyanis Rodriguez-Vera, Xuefen Yin, Mohammed Almoslem, Karolin Romahn, Brian Cicali, Viera Lukacova, Rodrigo Cristofoletti, Stephan Schmidt

    Diterbitkan 2023-10-01
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  8. 8
    Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure

    Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure oleh Soyoung Kim, Brian Cicali, Michelle Pressly, Lais Da Silva, Thomas Wendl, Valvanera Vozmediano, Stephan Schmidt, Rodrigo Cristofoletti

    Diterbitkan 2023-05-01
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  9. 9
    Model-Informed Optimization of a Pediatric Clinical Pharmacokinetic Trial of a New Spironolactone Liquid Formulation

    Model-Informed Optimization of a Pediatric Clinical Pharmacokinetic Trial of a New Spironolactone Liquid Formulation oleh Manasa Tatipalli, Vijay Kumar Siripuram, Tao Long, Diana Shuster, Galina Bernstein, Pierre Martineau, Kim A. Cook, Rodrigo Cristofoletti, Stephan Schmidt, Valvanera Vozmediano

    Diterbitkan 2021-06-01
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  10. 10
    Physiologically‐based pharmacokinetics modeling to investigate formulation factors influencing the generic substitution of dabigatran etexilate

    Physiologically‐based pharmacokinetics modeling to investigate formulation factors influencing the generic substitution of dabigatran etexilate oleh Nashid Farhan, Rodrigo Cristofoletti, Sumit Basu, Sarah Kim, Karthik Lingineni, Sibo Jiang, Joshua D. Brown, Lanyan (Lucy) Fang, Lawrence J. Lesko, Stephan Schmidt

    Diterbitkan 2021-03-01
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  11. 11
    Leveraging Physiologically Based Modelling to Provide Insights on the Absorption of Paliperidone Extended-Release Formulation under Fed and Fasting Conditions

    Leveraging Physiologically Based Modelling to Provide Insights on the Absorption of Paliperidone Extended-Release Formulation under Fed and Fasting Conditions oleh Saima Subhani, Viera Lukacova, Chaejin Kim, Leyanis Rodriguez-Vera, Paula Muniz, Monica Rodriguez, Rodrigo Cristofoletti, Sandra Van Os, Elena Suarez, Stephan Schmidt, Valvanera Vozmediano

    Diterbitkan 2023-02-01
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  12. 12
    Adult and pediatric physiologically‐based biopharmaceutics modeling to explain lamotrigine immediate release absorption process

    Adult and pediatric physiologically‐based biopharmaceutics modeling to explain lamotrigine immediate release absorption process oleh Edilainy Rizzieri Caleffi‐Marchesini, Amanda Antunes Herling, Julia Macente, Rodolfo Hernandes Bonan, Priscila deFreitas Lima, Rafaela Moreno, Veriano Alexandre, Nitin Bharat Charbe, Fernanda Belincanta Borghi‐Pangoni, Rodrigo Cristofoletti, Andréa Diniz

    Diterbitkan 2024-02-01
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  13. 13
    Requirements, expectations, challenges and opportunities associated with training the next generation of pharmacometricians

    Requirements, expectations, challenges and opportunities associated with training the next generation of pharmacometricians oleh Stephan Schmidt, Valvanera Vozmediano, Rodrigo Cristofoletti, Sarah Kim, Zhoumeng Lin, Natalia deMoraes, Francine Azeredo, Brian Cicali, Hans Leuenberger, Joshua D. Brown, Jin Y. Jin, Cynthia J. Musante, Stacey Tannenbaum, Yaning Wang

    Diterbitkan 2023-07-01
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  14. 14
    Challenges in Permeability Assessment for Oral Drug Product Development

    Challenges in Permeability Assessment for Oral Drug Product Development oleh Mirko Koziolek, Patrick Augustijns, Constantin Berger, Rodrigo Cristofoletti, David Dahlgren, Janneke Keemink, Pär Matsson, Fiona McCartney, Marco Metzger, Mario Mezler, Janis Niessen, James E. Polli, Maria Vertzoni, Werner Weitschies, Jennifer Dressman

    Diterbitkan 2023-09-01
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  15. 15
    Regulatory utility of physiologically‐based pharmacokinetic modeling to support alternative bioequivalence approaches and risk assessment: A workshop summary report

    Regulatory utility of physiologically‐based pharmacokinetic modeling to support alternative bioequivalence approaches and risk assessment: A workshop summary report oleh Fang Wu, Youssef Mousa, Kimberly Raines, Chris Bode, Yu Chung Tsang, Rodrigo Cristofoletti, Hongling Zhang, Tycho Heimbach, Lanyan Fang, Filippos Kesisoglou, Amitava Mitra, James Polli, Myong‐Jin Kim, Jianghong Fan, Banu S. Zolnik, Duxin Sun, Yi Zhang, Liang Zhao

    Diterbitkan 2023-05-01
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