Hasil Pencarian - Robert J. Slack

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  1. 1
    The effect of divalent metal cations on the αv integrin binding site is ligand and integrin specific

    The effect of divalent metal cations on the αv integrin binding site is ligand and integrin specific oleh Eleanor R. Hall, Robert J. Slack

    Diterbitkan 2019-02-01
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  2. 2
    A Quantitative Human Red Blood Cell Agglutination Assay for Characterisation of Galectin Inhibitors

    A Quantitative Human Red Blood Cell Agglutination Assay for Characterisation of Galectin Inhibitors oleh Rhianna Gasson, James A. Roper, Robert J. Slack

    Diterbitkan 2024-06-01
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  3. 3
    P1024: MYLOX-1: A PHASE II STUDY EVALUATING THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF ORAL LOXL2 INHIBITOR GB2064 (WITH FOCUS ON BONE MARROW COLLAGEN) IN PATIENTS WITH MYELOFIBROSIS

    P1024: MYLOX-1: A PHASE II STUDY EVALUATING THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF ORAL LOXL2 INHIBITOR GB2064 (WITH FOCUS ON BONE MARROW COLLAGEN) IN P... oleh Claire Harrison, John Mascarenhas, Daniela Cilloni, Richard Schlenk, Brian Jacoby, Robert J Slack, Vassilios Aslanis, Bhupinder Singh, Bertil Lindmark, Srdan Verstovsek, Raajit K Rampal

    Diterbitkan 2023-08-01
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  4. 4
    Resistance to anti-PD-1/anti-PD-L1: galectin-3 inhibition with GB1211 reverses galectin-3-induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1

    Resistance to anti-PD-1/anti-PD-L1: galectin-3 inhibition with GB1211 reverses galectin-3-induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1 oleh Joseph Mabbitt, Ian D. Holyer, James A. Roper, Ulf J. Nilsson, Fredrik R. Zetterberg, Lynda Vuong, Alison C. Mackinnon, Anders Pedersen, Robert J. Slack

    Diterbitkan 2023-08-01
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  5. 5
    Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance

    Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance oleh Henry Kim, Louis Kretz, Céline Ronin, Christina Starck, James A. Roper, Barbro Kahl-Knutson, Kristoffer Peterson, Hakon Leffler, Ulf J. Nilsson, Anders Pedersen, Fredrik R. Zetterberg, Robert J. Slack

    Diterbitkan 2024-06-01
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  6. 6
    The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis

    The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis oleh Paolo Comeglio, Giulia Guarnieri, Sandra Filippi, Ilaria Cellai, Gabriele Acciai, Ian Holyer, Fredrik Zetterberg, Hakon Leffler, Barbro Kahl-Knutson, Erica Sarchielli, Annamaria Morelli, Mario Maggi, Mario Maggi, Robert J. Slack, Linda Vignozzi, Linda Vignozzi

    Diterbitkan 2024-07-01
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  7. 7
    Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation

    Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation oleh Duncan C. Humphries, Duncan C. Humphries, Ross Mills, Cecilia Boz, Brian J. McHugh, Nikhil Hirani, Adriano G. Rossi, Anders Pedersen, Hans T. Schambye, Robert J. Slack, Hakon Leffler, Ulf J. Nilsson, Wei Wang, Tariq Sethi, Tariq Sethi, Alison C. Mackinnon, Alison C. Mackinnon

    Diterbitkan 2022-08-01
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  8. 8
    A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor

    A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ... oleh Toby M. Maher, Juliet K. Simpson, Joanna C. Porter, Frederick J. Wilson, Robert Chan, Rhena Eames, Yi Cui, Sarah Siederer, Simon Parry, Julia Kenny, Robert J. Slack, Jagdeep Sahota, Lyn Paul, Peter Saunders, Philip L. Molyneaux, Pauline T. Lukey, Gaia Rizzo, Graham E. Searle, Richard P. Marshall, Azeem Saleem, Arthur R. Kang’ombe, David Fairman, William A. Fahy, Mitra Vahdati-Bolouri

    Diterbitkan 2020-03-01
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  9. 9
    Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

    Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis oleh Alison E. John, Rebecca H. Graves, K. Tao Pun, Giovanni Vitulli, Ellen J. Forty, Paul F. Mercer, Josie L. Morrell, John W. Barrett, Rebecca F. Rogers, Maryam Hafeji, Lloyd I. Bibby, Elaine Gower, Valerie S. Morrison, Yim Man, James A. Roper, Jeni C. Luckett, Lee A. Borthwick, Ben S. Barksby, Rachel A. Burgoyne, Rory Barnes, Joelle Le, David J. Flint, Susan Pyne, Anthony Habgood, Louise A. Organ, Chitra Joseph, Rochelle C. Edwards-Pritchard, Toby M. Maher, Andrew J. Fisher, Natasja Stæhr Gudmann, Diana J. Leeming, Rachel C. Chambers, Pauline T. Lukey, Richard P. Marshall, Simon J. F. Macdonald, R. Gisli Jenkins, Robert J. Slack

    Diterbitkan 2020-09-01
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