Hasil Pencarian - Richard B Lock

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  1. 1
    Exploring the Metabolic Landscape of AML: From Haematopoietic Stem Cells to Myeloblasts and Leukaemic Stem Cells

    Exploring the Metabolic Landscape of AML: From Haematopoietic Stem Cells to Myeloblasts and Leukaemic Stem Cells oleh Yashar Mesbahi, Yashar Mesbahi, Yashar Mesbahi, Toby N. Trahair, Toby N. Trahair, Toby N. Trahair, Richard B. Lock, Richard B. Lock, Richard B. Lock, Patrick Connerty, Patrick Connerty, Patrick Connerty

    Diterbitkan 2022-02-01
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  2. 2
    Circulating Tumor DNA in Pediatric Cancer

    Circulating Tumor DNA in Pediatric Cancer oleh Louise Doculara, Louise Doculara, Louise Doculara, Toby N. Trahair, Toby N. Trahair, Toby N. Trahair, Narges Bayat, Narges Bayat, Narges Bayat, Richard B. Lock, Richard B. Lock, Richard B. Lock

    Diterbitkan 2022-05-01
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  3. 3
    Long Non-coding RNAs: Major Regulators of Cell Stress in Cancer

    Long Non-coding RNAs: Major Regulators of Cell Stress in Cancer oleh Patrick Connerty, Richard B. Lock, Charles E. de Bock

    Diterbitkan 2020-03-01
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  4. 4
    The Promise of Single-cell Technology in Providing New Insights Into the Molecular Heterogeneity and Management of Acute Lymphoblastic Leukemia

    The Promise of Single-cell Technology in Providing New Insights Into the Molecular Heterogeneity and Management of Acute Lymphoblastic Leukemia oleh Holly C.L. Pearson, Kooper V. Hunt, Toby N. Trahair, Richard B. Lock, Heather J. Lee, Charles E. de Bock

    Diterbitkan 2022-06-01
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  5. 5
    Disparate in vivo efficacy of FTY720 in xenograft models of Philadelphia positive and negative B-lineage acute lymphoblastic leukemia.

    Disparate in vivo efficacy of FTY720 in xenograft models of Philadelphia positive and negative B-lineage acute lymphoblastic leukemia. oleh Craig T Wallington-Beddoe, Anthony S Don, John Hewson, Qiao Qiao, Rachael A Papa, Richard B Lock, Kenneth F Bradstock, Linda J Bendall

    Diterbitkan 2012-01-01
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  6. 6
    Correction: Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia.

    Correction: Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia. oleh Craig T. Wallington-Beddoe, Anthony S. Don, John Hewson, Qiao Qiao, Rachael A. Papa, Richard B. Lock, Kenneth F. Bradstock, Linda J. Bendall

    Diterbitkan 2012-01-01
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  7. 7
    Development of siRNA-Loaded Lipid Nanoparticles Targeting Long Non-Coding RNA LINC01257 as a Novel and Safe Therapeutic Approach for t(8;21) Pediatric Acute Myeloid Leukemia

    Development of siRNA-Loaded Lipid Nanoparticles Targeting Long Non-Coding RNA LINC01257 as a Novel and Safe Therapeutic Approach for t(8;21) Pediatric Acute Myeloid Leukemia oleh Patrick Connerty, Ernest Moles, Charles E. de Bock, Nisitha Jayatilleke, Jenny L. Smith, Soheil Meshinchi, Chelsea Mayoh, Maria Kavallaris, Richard B. Lock

    Diterbitkan 2021-10-01
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  8. 8
    Epigenetic Silencing of the Proapoptotic Gene BIM in Anaplastic Large Cell Lymphoma through an MeCP2/SIN3a Deacetylating Complex

    Epigenetic Silencing of the Proapoptotic Gene BIM in Anaplastic Large Cell Lymphoma through an MeCP2/SIN3a Deacetylating Complex oleh Rocco Piazza, Vera Magistroni, Angela Mogavero, Federica Andreoni, Chiara Ambrogio, Roberto Chiarle, Luca Mologni, Petra S Bachmann, Richard B Lock, Paola Collini, Giuseppe Pelosi, Carlo Gambacorti-Passerini

    Diterbitkan 2013-05-01
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  9. 9
    Pharmacokinetic modeling of an induction regimen for in vivo combined testing of novel drugs against pediatric acute lymphoblastic leukemia xenografts.

    Pharmacokinetic modeling of an induction regimen for in vivo combined testing of novel drugs against pediatric acute lymphoblastic leukemia xenografts. oleh Barbara Szymanska, Urszula Wilczynska-Kalak, Min H Kang, Natalia L M Liem, Hernan Carol, Ingrid Boehm, Daniel Groepper, C Patrick Reynolds, Clinton F Stewart, Richard B Lock

    Diterbitkan 2012-01-01
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  10. 10
    Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute lymphoblastic leukemia

    Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute lymphoblastic... oleh Laurence C. Cheung, Mark N. Cruickshank, Anastasia M. Hughes, Sajla Singh, Grace-Alyssa Chua, Jette Ford, Emanuela Ferrari, Joyce Oommen, Sébastien Malinge, Richard B. Lock, Ursula R. Kees, Rishi S. Kotecha

    Diterbitkan 2019-07-01
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  11. 11
    PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia

    PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia oleh Kinjal Shah, Ahmad Nasimian, Mehreen Ahmed, Lina Al Ashiri, Linn Denison, Wondossen Sime, Katerina Bendak, Iryna Kolosenko, Valentina Siino, Fredrik Levander, Caroline Palm-Apergi, Ramin Massoumi, Richard B. Lock, Julhash U. Kazi

    Diterbitkan 2023-09-01
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  12. 12
    <i>ETV6::ACSL6</i> translocation-driven super-enhancer activation leads to eosinophilia in acute lymphoblastic leukemia through IL-3 overexpression

    <i>ETV6::ACSL6</i> translocation-driven super-enhancer activation leads to eosinophilia in acute lymphoblastic leukemia through IL-3 overexpression oleh Wenqian Xu, Feng Tian, Xiaolu Tai, Gaoxian Song, Yuanfang Liu, Liquan Fan, Xiangqin Weng, Eunjeong Yang, Meng Wang, Martin Bornhäuser, Chao Zhang, Richard B. Lock, Jason W.H. Wong, Jin Wang, Duohui Jing, Jian-Qing Mi

    Diterbitkan 2024-02-01
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  13. 13
    Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice

    Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice oleh Erwin M. Lee, Dean Yee, Samantha J. Busfield, Julie F. McManus, Nik Cummings, Gino Vairo, Andrew Wei, Hayley S. Ramshaw, Jason A. Powell, Angel F. Lopez, Ian D. Lewis, Martin N. McCall, Richard B. Lock

    Diterbitkan 2015-07-01
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  14. 14
    T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development

    T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development oleh Charles E. de Bock, Michelle Down, Kinsha Baidya, Bram Sweron, Andrew W. Boyd, Mark Fiers, Gordon F. Burns, Timothy J. Molloy, Richard B. Lock, Jean Soulier, Tom Taghon, Pieter Van Vlierberghe, Jan Cools, Jeff Holst, Rick F. Thorne

    Diterbitkan 2019-05-01
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  15. 15
    Author Correction: Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells

    Author Correction: Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells oleh Cedric S. Tremblay, Sung Kai Chiu, Jesslyn Saw, Hannah McCalmont, Veronique Litalien, Jacqueline Boyle, Stefan E. Sonderegger, Ngoc Chau, Kathryn Evans, Loretta Cerruti, Jessica M. Salmon, Adam McCluskey, Richard B. Lock, Phillip J. Robinson, Stephen M. Jane, David J. Curtis

    Diterbitkan 2021-02-01
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  16. 16
    Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells

    Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells oleh Cedric S. Tremblay, Sung Kai Chiu, Jesslyn Saw, Hannah McCalmont, Veronique Litalien, Jacqueline Boyle, Stefan E. Sonderegger, Ngoc Chau, Kathryn Evans, Loretta Cerruti, Jessica M. Salmon, Adam McCluskey, Richard B. Lock, Phillip J. Robinson, Stephen M. Jane, David J. Curtis

    Diterbitkan 2020-12-01
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  17. 17
    The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression

    The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression oleh Lin Xiao, Lin Xiao, Mawar Karsa, Mawar Karsa, Emma Ronca, Angelika Bongers, Angelika Kosciolek, Ali El-Ayoubi, Jezrael L. Revalde, Jezrael L. Revalde, Janith A. Seneviratne, Janith A. Seneviratne, Belamy B. Cheung, Belamy B. Cheung, Laurence C. Cheung, Laurence C. Cheung, Laurence C. Cheung, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha, Andrea Newbold, Andrea Newbold, Stefan Bjelosevic, Stefan Bjelosevic, Greg M. Arndt, Greg M. Arndt, Greg M. Arndt, Richard B. Lock, Richard B. Lock, Ricky W. Johnstone, Ricky W. Johnstone, Andrei V. Gudkov, Katerina V. Gurova, Michelle Haber, Michelle Haber, Murray D. Norris, Murray D. Norris, Murray D. Norris, Michelle J. Henderson, Michelle J. Henderson, Klaartje Somers, Klaartje Somers

    Diterbitkan 2022-05-01
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  18. 18
    Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 Inhibitors

    Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 Inhibitors oleh Michaela Waibel, Vanessa S. Solomon, Deborah A. Knight, Rachael A. Ralli, Sang-Kyu Kim, Kellie-Marie Banks, Eva Vidacs, Clemence Virely, Keith C.S. Sia, Lauryn S. Bracken, Racquel Collins-Underwood, Christina Drenberg, Laura B. Ramsey, Sara C. Meyer, Megumi Takiguchi, Ross A. Dickins, Ross Levine, Jacques Ghysdael, Mark A. Dawson, Richard B. Lock, Charles G. Mullighan, Ricky W. Johnstone

    Diterbitkan 2013-11-01
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  19. 19
    TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells

    TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells oleh Peter Truong, Sylvie Shen, Swapna Joshi, Md Imtiazul Islam, Ling Zhong, Mark J. Raftery, Ali Afrasiabi, Hamid Alinejad-Rokny, Mary Nguyen, Xiaoheng Zou, Golam Sarower Bhuyan, Chowdhury H. Sarowar, Elaheh S. Ghodousi, Olivia Stonehouse, Sara Mohamed, Cara E. Toscan, Patrick Connerty, Purvi M. Kakadia, Stefan K. Bohlander, Katharine A. Michie, Jonas Larsson, Richard B. Lock, Carl R. Walkley, Julie A. I. Thoms, Christopher J. Jolly, John E. Pimanda

    Diterbitkan 2024-08-01
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  20. 20
    Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia

    Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia oleh Quentin Van Thillo, Jolien De Bie, Janith A. Seneviratne, Sofie Demeyer, Sofia Omari, Anushree Balachandran, Vicki Zhai, Wai L. Tam, Bram Sweron, Ellen Geerdens, Olga Gielen, Sarah Provost, Heidi Segers, Nancy Boeckx, Glenn M. Marshall, Belamy B. Cheung, Kiyotaka Isobe, Itaru Kato, Junko Takita, Timothy G. Amos, Ira W. Deveson, Hannah McCalmont, Richard B. Lock, Ethan P. Oxley, Maximilian M. Garwood, Ross A. Dickins, Anne Uyttebroeck, Daniel R. Carter, Jan Cools, Charles E. de Bock

    Diterbitkan 2021-07-01
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