Hasil Pencarian - Ram Kannan

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  1. 1
    The CRISPR revolution and its impact on cancer research

    The CRISPR revolution and its impact on cancer research oleh Ram Kannan, Andrea Ventura

    Diterbitkan 2015-11-01
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  2. 2
    Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degeneration

    Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degenerat... oleh Parameswaran G. Sreekumar, Ram Kannan

    Diterbitkan 2020-10-01
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  3. 3
    Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin

    Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin oleh Parameswaran G Sreekumar, David R Hinton, Ram Kannan

    Diterbitkan 2017-01-01
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  4. 4
    Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration

    Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration oleh Parameswaran G. Sreekumar, Deborah A. Ferrington, Ram Kannan

    Diterbitkan 2021-04-01
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  5. 5
    Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells

    Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells oleh Parameswaran G Sreekumar, Mo Wang, Christine Spee, Srinivas R. Sadda, Ram Kannan

    Diterbitkan 2020-05-01
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  6. 6
    The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration Pathology

    The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration Pathology oleh Juha M. T. Hyttinen, Ram Kannan, Szabolcs Felszeghy, Minna Niittykoski, Antero Salminen, Kai Kaarniranta

    Diterbitkan 2019-11-01
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  7. 7
    Protection of retina by αB crystallin in sodium iodate induced retinal degeneration.

    Protection of retina by αB crystallin in sodium iodate induced retinal degeneration. oleh Peng Zhou, Ram Kannan, Christine Spee, Parameswaran G Sreekumar, Guorui Dou, David R Hinton

    Diterbitkan 2014-01-01
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  8. 8
    Mechanisms of Epithelial-Mesenchymal Transition and Prevention of Dispase-Induced PVR by Delivery of an Antioxidant αB Crystallin Peptide

    Mechanisms of Epithelial-Mesenchymal Transition and Prevention of Dispase-Induced PVR by Delivery of an Antioxidant αB Crystallin Peptide oleh Iori Wada, Parameswaran G Sreekumar, Christine Spee, Andrew J MacKay, Michael Ip, Ram Kannan

    Diterbitkan 2022-10-01
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  9. 9
    Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and <i>Ldlr</i><sup>−/−</sup> Mice

    Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and <i>Ldlr</i><sup>−/−</sup> Mice oleh Parameswaran Gangadharan Sreekumar, Feng Su, Christine Spee, Eduardo Araujo, Steven Nusinowitz, Srinivasa T Reddy, Ram Kannan

    Diterbitkan 2022-12-01
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  10. 10
    Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux.

    Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux. oleh Parameswaran G Sreekumar, Christine Spee, Stephen J Ryan, Susan P C Cole, Ram Kannan, David R Hinton

    Diterbitkan 2012-01-01
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  11. 11
    αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells.

    αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells. oleh Parameswaran G Sreekumar, Ram Kannan, Mizuki Kitamura, Christine Spee, Ernesto Barron, Stephen J Ryan, David R Hinton

    Diterbitkan 2010-10-01
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  12. 12
    Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione.

    Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione. oleh Douglas Matsunaga, Parameswaran G Sreekumar, Keijiro Ishikawa, Hiroto Terasaki, Ernesto Barron, Pinchas Cohen, Ram Kannan, David R Hinton

    Diterbitkan 2016-01-01
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  13. 13
    Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice

    Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice oleh Parameswaran Gangadharan Sreekumar, Feng Su, Christine Spee, Elise Hong, Ravikiran Komirisetty, Eduardo Araujo, Steven Nusinowitz, Srinivasa T. Reddy, Ram Kannan

    Diterbitkan 2023-09-01
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  14. 14
    The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma

    The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma oleh Jacob T Polaski, Dylan B Udy, Luisa F Escobar-Hoyos, Gokce Askan, Steven D Leach, Andrea Ventura, Ram Kannan, Robert K Bradley

    Diterbitkan 2021-01-01
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  15. 15
    Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target

    Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target oleh Peter J. Cook, Rozario Thomas, Ram Kannan, Esther Sanchez de Leon, Alexander Drilon, Marc K. Rosenblum, Maurizio Scaltriti, Robert Benezra, Andrea Ventura

    Diterbitkan 2017-07-01
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  16. 16
    Correction: Author Correction: Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target

    Correction: Author Correction: Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target oleh Peter J. Cook, Rozario Thomas, Ram Kannan, Esther Sanchez de Leon, Alexander Drilon, Marc K. Rosenblum, Maurizio Scaltriti, Robert Benezra, Andrea Ventura

    Diterbitkan 2018-03-01
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  17. 17
    A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration

    A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration oleh Feng Su, Christine Spee, Eduardo Araujo, Eric Barron, Mo Wang, Caleb Ghione, David R. Hinton, Steven Nusinowitz, Ram Kannan, Srinivasa T. Reddy, Robin Farias-Eisner

    Diterbitkan 2019-09-01
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  18. 18
    αB-Crystallin Peptide Fused with Elastin-like Polypeptide: Intracellular Activity in Retinal Pigment Epithelial Cells Challenged with Oxidative Stress

    αB-Crystallin Peptide Fused with Elastin-like Polypeptide: Intracellular Activity in Retinal Pigment Epithelial Cells Challenged with Oxidative Stress oleh Sara Aly Attia, Anh Tan Truong, Alvin Phan, Shin-Jae Lee, Manal Abanmai, Marinella Markanovic, Hugo Avila, Haozhong Luo, Atham Ali, Parameswaran G. Sreekumar, Ram Kannan, J. Andrew MacKay

    Diterbitkan 2023-09-01
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  19. 19
    Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

    Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration oleh Szabolcs Felszeghy, Johanna Viiri, Jussi J. Paterno, Juha M.T. Hyttinen, Ali Koskela, Mei Chen, Henri Leinonen, Heikki Tanila, Niko Kivinen, Arto Koistinen, Elisa Toropainen, Marialaura Amadio, Adrian Smedowski, Mika Reinisalo, Mateusz Winiarczyk, Jerzy Mackiewicz, Maija Mutikainen, Anna-Kaisa Ruotsalainen, Mikko Kettunen, Kimmo Jokivarsi, Debasish Sinha, Kati Kinnunen, Goran Petrovski, Janusz Blasiak, Geir Bjørkøy, Ari Koskelainen, Heli Skottman, Arto Urtti, Antero Salminen, Ram Kannan, Deborah A. Ferrington, Heping Xu, Anna-Liisa Levonen, Pasi Tavi, Anu Kauppinen, Kai Kaarniranta

    Diterbitkan 2019-01-01
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