Hasil Pencarian - Rachel Brough

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  1. 1
    Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer

    Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer oleh Agnieszka K. Witkiewicz, Sejin Chung, Rachel Brough, Paris Vail, Jorge Franco, Christopher J. Lord, Erik S. Knudsen

    Diterbitkan 2018-01-01
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  2. 2
    Correction: Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

    Correction: Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. oleh Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Diterbitkan 2018-01-01
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  3. 3
    Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

    Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. oleh Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Diterbitkan 2017-01-01
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  4. 4
    CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

    CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. oleh Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Diterbitkan 2016-01-01
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  5. 5
    Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

    Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. oleh Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Diterbitkan 2016-01-01
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  6. 6
    A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity.

    A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity. oleh Stephen J Pettitt, Farah L Rehman, Ilirjana Bajrami, Rachel Brough, Fredrik Wallberg, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, Lina Chen, James Campbell, Christopher J Lord, Alan Ashworth

    Diterbitkan 2013-01-01
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  7. 7
    Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency

    Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency oleh Ilirjana Bajrami, Callum Walker, Dragomir B. Krastev, Daniel Weekes, Feifei Song, Andrew J. Wicks, John Alexander, Syed Haider, Rachel Brough, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

    Diterbitkan 2021-11-01
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  8. 8
    Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

    Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7 oleh Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

    Diterbitkan 2024-02-01
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  9. 9
    ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A

    ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A oleh Chris T. Williamson, Rowan Miller, Helen N. Pemberton, Samuel E. Jones, James Campbell, Asha Konde, Nicholas Badham, Rumana Rafiq, Rachel Brough, Aditi Gulati, Colm J. Ryan, Jeff Francis, Peter B. Vermulen, Andrew R. Reynolds, Philip M. Reaper, John R. Pollard, Alan Ashworth, Christopher J. Lord

    Diterbitkan 2016-12-01
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  10. 10
    Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

    Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance oleh Stephen J. Pettitt, Dragomir B. Krastev, Inger Brandsma, Amy Dréan, Feifei Song, Radoslav Aleksandrov, Maria I. Harrell, Malini Menon, Rachel Brough, James Campbell, Jessica Frankum, Michael Ranes, Helen N. Pemberton, Rumana Rafiq, Kerry Fenwick, Amanda Swain, Sebastian Guettler, Jung-Min Lee, Elizabeth M. Swisher, Stoyno Stoynov, Kosuke Yusa, Alan Ashworth, Christopher J. Lord

    Diterbitkan 2018-05-01
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  11. 11
    Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

    Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines oleh James Campbell, Colm J. Ryan, Rachel Brough, Ilirjana Bajrami, Helen N. Pemberton, Irene Y. Chong, Sara Costa-Cabral, Jessica Frankum, Aditi Gulati, Harriet Holme, Rowan Miller, Sophie Postel-Vinay, Rumana Rafiq, Wenbin Wei, Chris T. Williamson, David A. Quigley, Joe Tym, Bissan Al-Lazikani, Timothy Fenton, Rachael Natrajan, Sandra J. Strauss, Alan Ashworth, Christopher J. Lord

    Diterbitkan 2016-03-01
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  12. 12
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells

    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells oleh Anabel Zelceski, Paola Francica, Lea Lingg, Merve Mutlu, Colin Stok, Martin Liptay, John Alexander, Joseph S. Baxter, Rachel Brough, Aditi Gulati, Syed Haider, Maya Raghunandan, Feifei Song, Sandhya Sridhar, Josep V. Forment, Mark J. O’Connor, Barry R. Davies, Marcel A.T.M. van Vugt, Dragomir B. Krastev, Stephen J. Pettitt, Andrew N.J. Tutt, Sven Rottenberg, Christopher J. Lord

    Diterbitkan 2023-05-01
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  13. 13
    Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

    Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance oleh Diana Zatreanu, Helen M. R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, Diego Grande, Vera Grinkevich, Robert A. Heald, Sophie Langdon, Jayesh Majithiya, Claire McWhirter, Niall M. B. Martin, Shaun Moore, Joana Neves, Eeson Rajendra, Marco Ranzani, Theresia Schaedler, Martin Stockley, Kimberley Wiggins, Rachel Brough, Sandhya Sridhar, Aditi Gulati, Nan Shao, Luned M. Badder, Daniela Novo, Eleanor G. Knight, Rebecca Marlow, Syed Haider, Elsa Callen, Graeme Hewitt, Joost Schimmel, Remko Prevo, Christina Alli, Amanda Ferdinand, Cameron Bell, Peter Blencowe, Chris Bot, Mathew Calder, Mark Charles, Jayne Curry, Tennyson Ekwuru, Katherine Ewings, Wojciech Krajewski, Ellen MacDonald, Hollie McCarron, Leon Pang, Chris Pedder, Laurent Rigoreau, Martin Swarbrick, Ed Wheatley, Simon Willis, Ai Ching Wong, Andre Nussenzweig, Marcel Tijsterman, Andrew Tutt, Simon J. Boulton, Geoff S. Higgins, Stephen J. Pettitt, Graeme C. M. Smith, Christopher J. Lord

    Diterbitkan 2021-06-01
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