Hasil Pencarian - R. Luke Wiseman

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  1. 1
    Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress

    Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress oleh T. Kelly Rainbolt, Justine Lebeau, Cristina Puchades, R. Luke Wiseman

    Diterbitkan 2016-03-01
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  2. 2
    Modulating protein quality control

    Modulating protein quality control oleh Lars Plate, Ryan J Paxman, R Luke Wiseman, Jeffery W Kelly

    Diterbitkan 2016-07-01
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  3. 3
    Defining the Functional Targets of Cap‘n’collar Transcription Factors NRF1, NRF2, and NRF3

    Defining the Functional Targets of Cap‘n’collar Transcription Factors NRF1, NRF2, and NRF3 oleh Lara Ibrahim, Jaleh Mesgarzadeh, Ian Xu, Evan T. Powers, R. Luke Wiseman, Michael J. Bollong

    Diterbitkan 2020-10-01
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  4. 4
    Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins

    Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins oleh Ryan Paxman, Lars Plate, Erik A Blackwood, Chris Glembotski, Evan T Powers, R Luke Wiseman, Jeffery W Kelly

    Diterbitkan 2018-08-01
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  5. 5
    Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity

    Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity oleh Jessica D. Rosarda, Sarah Giles, Sarah Harkins-Perry, Elizabeth A. Mills, Martin Friedlander, R. Luke Wiseman, Kevin T. Eade

    Diterbitkan 2023-07-01
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  6. 6
    The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress

    The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress oleh Justine Lebeau, Jaclyn M. Saunders, Vivian W.R. Moraes, Aparajita Madhavan, Nicole Madrazo, Mary C. Anthony, R. Luke Wiseman

    Diterbitkan 2018-03-01
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  7. 7
    Structures of the human LONP1 protease reveal regulatory steps involved in protease activation

    Structures of the human LONP1 protease reveal regulatory steps involved in protease activation oleh Mia Shin, Edmond R. Watson, Albert S. Song, Jeffrey T. Mindrebo, Scott J. Novick, Patrick R. Griffin, R. Luke Wiseman, Gabriel C. Lander

    Diterbitkan 2021-05-01
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  8. 8
    Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis

    Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis oleh Erik A. Blackwood, Khalid Azizi, Donna J. Thuerauf, Ryan J. Paxman, Lars Plate, Jeffery W. Kelly, R. Luke Wiseman, Christopher C. Glembotski

    Diterbitkan 2019-01-01
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  9. 9
    ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors

    ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors oleh Jaleh S. Mesgarzadeh, Isabelle C. Romine, Ethan M. Smith-Cohen, Julia M. D. Grandjean, Jeffery W. Kelly, Joseph C. Genereux, R. Luke Wiseman

    Diterbitkan 2022-05-01
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  10. 10
    Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and Blastocysts

    Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and Blastocysts oleh Oktay Kirak, Eugene Ke, Kevin Y. Yang, Anna Schwarz, Lars Plate, Amy Nham, Justin R. Abadejos, Anna Valencia, R. Luke Wiseman, Kathy O. Lui, Manching Ku

    Diterbitkan 2020-08-01
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  11. 11
    Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors

    Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors oleh Meng Wang, Edmund Cotter, Ya-Juan Wang, Xu Fu, Angela L. Whittsette, Joseph W. Lynch, R. Luke Wiseman, Jeffery W. Kelly, Angelo Keramidas, Ting-Wei Mu

    Diterbitkan 2022-04-01
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  12. 12
    Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity

    Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity oleh Aparajita Madhavan, Bernard P. Kok, Bibiana Rius, Julia M. D. Grandjean, Adekunle Alabi, Verena Albert, Ara Sukiasyan, Evan T. Powers, Andrea Galmozzi, Enrique Saez, R. Luke Wiseman

    Diterbitkan 2022-02-01
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  13. 13
    Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

    Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments oleh Matthew D. Shoulders, Lisa M. Ryno, Joseph C. Genereux, James J. Moresco, Patricia G. Tu, Chunlei Wu, John R. Yates, III, Andrew I. Su, Jeffery W. Kelly, R. Luke Wiseman

    Diterbitkan 2013-04-01
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  14. 14
    Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation

    Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation oleh Lars Plate, Christina B Cooley, John J Chen, Ryan J Paxman, Ciara M Gallagher, Franck Madoux, Joseph C Genereux, Wesley Dobbs, Dan Garza, Timothy P Spicer, Louis Scampavia, Steven J Brown, Hugh Rosen, Evan T Powers, Peter Walter, Peter Hodder, R Luke Wiseman, Jeffery W Kelly

    Diterbitkan 2016-07-01
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