Hasil Pencarian - Petr Pavek

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  1. 1
    Pregnane X receptor (PXR)-mediated gene repression and cross-talk of PXR with other nuclear receptors via coactivator interactions

    Pregnane X receptor (PXR)-mediated gene repression and cross-talk of PXR with other nuclear receptors via coactivator interactions oleh Petr Pavek

    Diterbitkan 2016-11-01
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  2. 2
    The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists

    The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists oleh Alejandro Carazo, Petr Pávek

    Diterbitkan 2015-04-01
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  3. 3
    Resveratrol as an Inhibitor of Pregnane X Receptor (PXR): Another Lesson in PXR Antagonism

    Resveratrol as an Inhibitor of Pregnane X Receptor (PXR): Another Lesson in PXR Antagonism oleh Tomas Smutny, Petr Pavek

    Diterbitkan 2014-01-01
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  4. 4
    Marine Ligands of the Pregnane X Receptor (PXR): An Overview

    Marine Ligands of the Pregnane X Receptor (PXR): An Overview oleh Alejandro Carazo, Přemysl Mladěnka, Petr Pávek

    Diterbitkan 2019-09-01
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  5. 5
    Allosteric Antagonism of the Pregnane X Receptor (PXR): Current-State-of-the-Art and Prediction of Novel Allosteric Sites

    Allosteric Antagonism of the Pregnane X Receptor (PXR): Current-State-of-the-Art and Prediction of Novel Allosteric Sites oleh Rajamanikkam Kamaraj, Martin Drastik, Jana Maixnerova, Petr Pavek

    Diterbitkan 2022-09-01
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  6. 6
    Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction

    Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction oleh Jurjen Duintjer Tebbens, Malek Azar, Elfriede Friedmann, Martin Lanzendörfer, Petr Pávek

    Diterbitkan 2018-06-01
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  7. 7
    Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS)

    Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS) oleh Jana Kubackova, Ondrej Holas, Jarmila Zbytovska, Barbora Vranikova, Guanghong Zeng, Petr Pavek, Anette Mullertz

    Diterbitkan 2021-03-01
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  8. 8
    Radiolabeled 15-mer peptide internalization is mediated by megalin (LRP2 receptor) in a CRISPR/Cas9-based LRP2 knockout human kidney cell model

    Radiolabeled 15-mer peptide internalization is mediated by megalin (LRP2 receptor) in a CRISPR/Cas9-based LRP2 knockout human kidney cell model oleh Anna Durinova, Lucie Smutna, Pavel Barta, Rajamanikkam Kamaraj, Tomas Smutny, Bernhard Schmierer, Petr Pavek, Frantisek Trejtnar

    Diterbitkan 2024-04-01
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  9. 9
    Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver

    Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver oleh Michaela Šadibolová, Tomáš Zárybnický, Tomáš Smutný, Petr Pávek, Zdeněk Šubrt, Petra Matoušková, Lenka Skálová, Iva Boušová

    Diterbitkan 2019-09-01
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  10. 10
    The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids

    The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids oleh Tomas Smutny, Jan Dusek, Lucie Hyrsova, Jana Nekvindova, Alzbeta Horvatova, Stanislav Micuda, Sabine Gerbal-Chaloin, Petr Pavek

    Diterbitkan 2020-01-01
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  11. 11
    Higher Risk of Cardiovascular Diseases in Rheumatoid Arthritis Patients Without Methotrexate Treatment

    Higher Risk of Cardiovascular Diseases in Rheumatoid Arthritis Patients Without Methotrexate Treatment oleh Karel Hloch, Martin Doseděl, Jurjen Duintjer Tebbens, Lenka Žaloudková, Helena Medková, Jiří Vlček, Tomáš Soukup, Petr Pávek

    Diterbitkan 2021-11-01
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  12. 12
    Multidrug Resistance-Associated Protein 2 Deficiency Aggravates Estrogen-Induced Impairment of Bile Acid Metabolomics in Rats

    Multidrug Resistance-Associated Protein 2 Deficiency Aggravates Estrogen-Induced Impairment of Bile Acid Metabolomics in Rats oleh Fatemeh Alaei Faradonbeh, Hana Lastuvkova, Jolana Cermanova, Milos Hroch, Zuzana Nova, Martin Uher, Petra Hirsova, Petr Pavek, Stanislav Micuda

    Diterbitkan 2022-03-01
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  13. 13
    Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling

    Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling oleh Alejandro Carazo, Alejandro Carazo, Jan Dusek, Ondrej Holas, Josef Skoda, Lucie Hyrsova, Tomas Smutny, Tomas Soukup, Martin Dosedel, Petr Pávek

    Diterbitkan 2018-10-01
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  14. 14
    Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain

    Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain oleh Josef Skoda, Jan Dusek, Martin Drastik, Alzbeta Stefela, Klara Dohnalova, Karel Chalupsky, Tomas Smutny, Stanislav Micuda, Sabine Gerbal-Chaloin, Petr Pavek

    Diterbitkan 2020-11-01
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  15. 15
    (E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells

    (E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimu... oleh Alzbeta Stefela, Miroslav Kaspar, Miroslav Kaspar, Martin Drastik, Thales Kronenberger, Thales Kronenberger, Stanislav Micuda, Martin Dracinsky, Blanka Klepetarova, Eva Kudova, Petr Pavek

    Diterbitkan 2021-08-01
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  16. 16
    PLGA Based Nanospheres as a Potent Macrophage-Specific Drug Delivery System

    PLGA Based Nanospheres as a Potent Macrophage-Specific Drug Delivery System oleh Barbora Boltnarova, Jana Kubackova, Josef Skoda, Alzbeta Stefela, Monika Smekalova, Petra Svacinova, Ivona Pavkova, Milan Dittrich, Daniel Scherman, Jarmila Zbytovska, Petr Pavek, Ondrej Holas

    Diterbitkan 2021-03-01
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  17. 17
    Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis

    Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis oleh Hana Lastuvkova, Fatemeh Alaei Faradonbeh, Jolana Schreiberova, Milos Hroch, Jaroslav Mokry, Hana Faistova, Zuzana Nova, Radomír Hyspler, Ivone Cristina Igreja Sa, Petr Nachtigal, Alzbeta Stefela, Petr Pavek, Stanislav Micuda

    Diterbitkan 2021-06-01
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