Hasil Pencarian - Peter S Dragovich

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  1. 1
    Supplementation of Nicotinic Acid with NAMPT Inhibitors Results in Loss of In Vivo Efficacy in NAPRT1-Deficient Tumor Models

    Supplementation of Nicotinic Acid with NAMPT Inhibitors Results in Loss of In Vivo Efficacy in NAPRT1-Deficient Tumor Models oleh Thomas O'Brien, Jason Oeh, Yang Xiao, Xiaorong Liang, Alexander Vanderbilt, Ann Qin, Lulu Yang, Leslie B. Lee, Justin Ly, Ely Cosino, Jennifer A. LaCap, Annie Ogasawara, Simon Williams, Michelle Nannini, Bianca M. Liederer, Peter Jackson, Peter S. Dragovich, Deepak Sampath

    Diterbitkan 2013-12-01
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  2. 2
    Structural basis for resistance to diverse classes of NAMPT inhibitors.

    Structural basis for resistance to diverse classes of NAMPT inhibitors. oleh Weiru Wang, Kristi Elkins, Angela Oh, Yen-Ching Ho, Jiansheng Wu, Hong Li, Yang Xiao, Mandy Kwong, Mary Coons, Bobby Brillantes, Eric Cheng, Lisa Crocker, Peter S Dragovich, Deepak Sampath, Xiaozhang Zheng, Kenneth W Bair, Thomas O'Brien, Lisa D Belmont

    Diterbitkan 2014-01-01
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  3. 3
    Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs

    Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs oleh Donglu Zhang, Bin Ma, Peter S. Dragovich, Li Ma, Shu Chen, Eugene C. Chen, Xiaofen Ye, Joyce Liu, Jennifer Pizzano, Elizabeth Bortolon, Emily Chan, Xing Zhang, Yi-Chen Chen, Elizabeth S. Levy, Robert L. Yauch, S. Cyrus Khojasteh, Cornelis E. C. A. Hop

    Diterbitkan 2024-05-01
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  4. 4
    Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors

    Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors oleh Marc Kschonsak, Christine C Jao, Christopher P Arthur, Alexis L Rohou, Philippe Bergeron, Daniel F Ortwine, Steven J McKerrall, David H Hackos, Lunbin Deng, Jun Chen, Tianbo Li, Peter S Dragovich, Matthew Volgraf, Matthew R Wright, Jian Payandeh, Claudio Ciferri, John C Tellis

    Diterbitkan 2023-03-01
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  5. 5
    Improved translation of stability for conjugated antibodies using an in vitro whole blood assay

    Improved translation of stability for conjugated antibodies using an in vitro whole blood assay oleh Aimee Fourie-O’Donohue, Phillip Y. Chu, Josefa dela Cruz Chuh, Robert Tchelepi, Siao Ping Tsai, John C. Tran, William S. Sawyer, Dian Su, Carl Ng, Keyang Xu, Shang-Fan Yu, Thomas H. Pillow, Jack Sadowsky, Peter S. Dragovich, Yichin Liu, Katherine R. Kozak

    Diterbitkan 2020-01-01
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  6. 6
    Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response

    Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response oleh Josefa Dela Cruz Chuh, MaryAnn Go, Yvonne Chen, Jun Guo, Hanine Rafidi, Danielle Mandikian, Yonglian Sun, Zhonghua Lin, Kellen Schneider, Pamela Zhang, Rajesh Vij, Danielle Sharpnack, Pamela Chan, Cecile de la Cruz, Jack Sadowsky, Dhaya Seshasayee, James T. Koerber, Thomas H. Pillow, Gail D. Phillips, Rebecca K Rowntree, C. Andrew Boswell, Katherine R. Kozak, Andrew G. Polson, Paul Polakis, Shang-Fan Yu, Peter S. Dragovich, Nicholas J. Agard

    Diterbitkan 2021-01-01
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  7. 7
    Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers

    Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers oleh Jennifer Cantley, Xiaofen Ye, Emma Rousseau, Tom Januario, Brian D. Hamman, Christopher M. Rose, Tommy K. Cheung, Trent Hinkle, Leofal Soto, Connor Quinn, Alicia Harbin, Elizabeth Bortolon, Xin Chen, Roy Haskell, Eva Lin, Shang-Fan Yu, Geoff Del Rosario, Emily Chan, Debra Dunlap, Hartmut Koeppen, Scott Martin, Mark Merchant, Matt Grimmer, Fabio Broccatelli, Jing Wang, Jennifer Pizzano, Peter S. Dragovich, Michael Berlin, Robert L. Yauch

    Diterbitkan 2022-11-01
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  8. 8
    The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results

    The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results oleh Gail D. Lewis, Guangmin Li, Jun Guo, Shang-Fan Yu, Carter T. Fields, Genee Lee, Donglu Zhang, Peter S. Dragovich, Thomas Pillow, BinQing Wei, Jack Sadowsky, Douglas Leipold, Tim Wilson, Amrita Kamath, Michael Mamounas, M. Violet Lee, Ola Saad, Voleak Choeurng, Alexander Ungewickell, Sharareh Monemi, Lisa Crocker, Kevin Kalinsky, Shanu Modi, Kyung Hae Jung, Erika Hamilton, Patricia LoRusso, Ian Krop, Melissa M. Schutten, Renee Commerford, Mark X. Sliwkowski, Eunpi Cho

    Diterbitkan 2024-01-01
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