Search Results - Paul S. Mischel

Paul Mischel

Paul Mischel Paul S. Mischel (born July 13, 1962) is a physician-scientist whose laboratory has made pioneering discoveries in the pathogenesis of human cancer. He is the Fortinet Founders Professor, and Vice Chair for Research for the Department of Pathology, Stanford Medicine, an Institute Scholar in Sarafan ChEM-H. He is also a Faculty Advisor for Experimental Biology at the Innovative Medicines Accelerator at Stanford University. Mischel’s research published in a series of papers in ''Nature'' and ''Science'', has catalyzed a paradigm shift in precision oncology that promises to transform the diagnosis and treatment of patients suffering from some of the most aggressive forms of cancer. Provided by Wikipedia
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  1. 1
    Shared Intelligence: A Patient-Derived, Deeply Characterized Glioblastoma Cell Line Resource

    Shared Intelligence: A Patient-Derived, Deeply Characterized Glioblastoma Cell Line Resource by Genaro R. Villa, Paul S. Mischel

    Published 2015-10-01
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  2. 2
    When is hub gene selection better than standard meta-analysis?

    When is hub gene selection better than standard meta-analysis? by Peter Langfelder, Paul S Mischel, Steve Horvath

    Published 2013-01-01
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  3. 3
    Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling

    Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling by Feng Liu, Paul S. Mischel, Webster K. Cavenee

    Published 2017-03-01
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  4. 4
    Molecular and Genetic Determinants of Glioma Cell Invasion

    Molecular and Genetic Determinants of Glioma Cell Invasion by Kenta Masui, Yoichiro Kato, Tatsuo Sawada, Paul S. Mischel, Noriyuki Shibata

    Published 2017-12-01
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  5. 5
    BAP1 methylation: a prognostic marker of uveal melanoma metastasis

    BAP1 methylation: a prognostic marker of uveal melanoma metastasis by Mathieu F. Bakhoum, Ellis J. Curtis, Michael H. Goldbaum, Paul S. Mischel

    Published 2021-09-01
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  6. 6
    Protein Acetylation at the Interface of Genetics, Epigenetics and Environment in Cancer

    Protein Acetylation at the Interface of Genetics, Epigenetics and Environment in Cancer by Mio Harachi, Kenta Masui, Webster K. Cavenee, Paul S. Mischel, Noriyuki Shibata

    Published 2021-04-01
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  7. 7
    mTOR Complexes as a Nutrient Sensor for Driving Cancer Progression

    mTOR Complexes as a Nutrient Sensor for Driving Cancer Progression by Mio Harachi, Kenta Masui, Yukinori Okamura, Ryota Tsukui, Paul S. Mischel, Noriyuki Shibata

    Published 2018-10-01
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  8. 8
    Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance

    Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance by Si-Han Wu, Jun-Feng Bi, Timothy Cloughesy, Webster K. Cavenee, Paul S. Mischel

    Published 2014-12-01
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  9. 9
    Challenges in identifying cancer genes by analysis of exome sequencing data

    Challenges in identifying cancer genes by analysis of exome sequencing data by Matan Hofree, Hannah Carter, Jason F. Kreisberg, Sourav Bandyopadhyay, Paul S. Mischel, Stephen Friend, Trey Ideker

    Published 2016-07-01
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  10. 10
    Transcriptional immune suppression and up-regulation of double-stranded DNA damage and repair repertoires in ecDNA-containing tumors

    Transcriptional immune suppression and up-regulation of double-stranded DNA damage and repair repertoires in ecDNA-containing tumors by Miin S Lin, Se-Young Jo, Jens Luebeck, Howard Y Chang, Sihan Wu, Paul S Mischel, Vineet Bafna

    Published 2024-06-01
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  11. 11
    Exploring the landscape of focal amplifications in cancer using AmpliconArchitect

    Exploring the landscape of focal amplifications in cancer using AmpliconArchitect by Viraj Deshpande, Jens Luebeck, Nam-Phuong D. Nguyen, Mehrdad Bakhtiari, Kristen M. Turner, Richard Schwab, Hannah Carter, Paul S. Mischel, Vineet Bafna

    Published 2019-01-01
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  12. 12
    Determining PTEN functional status by network component deduced transcription factor activities.

    Determining PTEN functional status by network component deduced transcription factor activities. by Linh M Tran, Chun-Ju Chang, Seema Plaisier, Shumin Wu, Julie Dang, Paul S Mischel, James C Liao, Thomas G Graeber, Hong Wu

    Published 2012-01-01
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  13. 13
    RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways.

    RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways. by Jun Muto, Takao Imai, Daisuke Ogawa, Yoshinori Nishimoto, Yohei Okada, Yo Mabuchi, Takeshi Kawase, Akio Iwanami, Paul S Mischel, Hideyuki Saya, Kazunari Yoshida, Yumi Matsuzaki, Hideyuki Okano

    Published 2012-01-01
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  14. 14
    Correction: RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI Kinase/Akt Signaling Pathways.

    Correction: RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI Kinase/Akt Signaling Pathways. by Jun Muto, Takao Imai, Daisuke Ogawa, Yoshinori Nishimoto, Yohei Okada, Yo Mabuchi, Takeshi Kawase, Akio Iwanami, Paul S. Mischel, Hideyuki Saya, Kazunari Yoshida, Yumi Matsuzaki, Hideyuki Okano

    Published 2013-01-01
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  15. 15
    Correction: RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI Kinase/Akt Signaling Pathways.

    Correction: RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI Kinase/Akt Signaling Pathways. by Jun Muto, Takao Imai, Daisuke Ogawa, Yoshinori Nishimoto, Yohei Okada, Yo Mabuchi, Takeshi Kawase, Akio Iwanami, Paul S. Mischel, Hideyuki Saya, Kazunari Yoshida, Yumi Matsuzaki, Hideyuki Okano

    Published 2012-01-01
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  16. 16
    AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications

    AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications by Jens Luebeck, Ceyda Coruh, Siavash R. Dehkordi, Joshua T. Lange, Kristen M. Turner, Viraj Deshpande, Dave A. Pai, Chao Zhang, Utkrisht Rajkumar, Julie A. Law, Paul S. Mischel, Vineet Bafna

    Published 2020-09-01
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  17. 17
    DNA hypomethylator phenotype reprograms glutamatergic network in receptor tyrosine kinase gene-mutated glioblastoma

    DNA hypomethylator phenotype reprograms glutamatergic network in receptor tyrosine kinase gene-mutated glioblastoma by Mio Harachi, Kenta Masui, Erika Shimizu, Kumiko Murakami, Hiromi Onizuka, Yoshihiro Muragaki, Takakazu Kawamata, Hisako Nakayama, Mariko Miyata, Takashi Komori, Webster K. Cavenee, Paul S. Mischel, Atsushi Kurata, Noriyuki Shibata

    Published 2024-03-01
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  18. 18
    Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.

    Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway. by Mohammad Atefi, Erika von Euw, Narsis Attar, Charles Ng, Connie Chu, Deliang Guo, Ramin Nazarian, Bartosz Chmielowski, John A Glaspy, Begonya Comin-Anduix, Paul S Mischel, Roger S Lo, Antoni Ribas

    Published 2011-01-01
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  19. 19
    A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma.

    A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma. by Renee D Read, Tim R Fenton, German G Gomez, Jill Wykosky, Scott R Vandenberg, Ivan Babic, Akio Iwanami, Huijun Yang, Webster K Cavenee, Paul S Mischel, Frank B Furnari, John B Thomas

    Published 2013-01-01
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  20. 20
    CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway.

    CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway. by Mayumi Jijiwa, Habibe Demir, Snehalata Gupta, Crystal Leung, Kaushal Joshi, Nicholas Orozco, Tiffany Huang, Vedat O Yildiz, Ichiyo Shibahara, Jason A de Jesus, William H Yong, Paul S Mischel, Soledad Fernandez, Harley I Kornblum, Ichiro Nakano

    Published 2011-01-01
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