Hasil Pencarian - Paul M. O'Neill

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  1. 1
    The Molecular Mechanism of Action of Artemisinin—The Debate Continues

    The Molecular Mechanism of Action of Artemisinin—The Debate Continues oleh Stephen A. Ward, Victoria E. Barton, Paul M. O’Neill

    Diterbitkan 2010-03-01
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  2. 2
    Structure-based bioisosteric design, synthesis and biological evaluation of novel pyrimidines as antiplasmodial antifolate agents

    Structure-based bioisosteric design, synthesis and biological evaluation of novel pyrimidines as antiplasmodial antifolate agents oleh Moaz M. Abdou, Paul M. O'Neill, Eric Amigues, Magdalini Matziari

    Diterbitkan 2022-11-01
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  3. 3
    Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions

    Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions oleh Moaz M. Abdou, Paul M. O’Neill, Eric Amigues, Magdalini Matziari

    Diterbitkan 2022-06-01
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  4. 4
    Antimalarial Agents as Therapeutic Tools Against Toxoplasmosis—A Short Bridge between Two Distant Illnesses

    Antimalarial Agents as Therapeutic Tools Against Toxoplasmosis—A Short Bridge between Two Distant Illnesses oleh Alina Secrieru, Inês C. C. Costa, Paul M. O'Neill, Maria L. S. Cristiano

    Diterbitkan 2020-03-01
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  5. 5
    Diastereoselective synthesis of a novel phosphinic peptide as ACE inhibitor: Fragment-based design approach

    Diastereoselective synthesis of a novel phosphinic peptide as ACE inhibitor: Fragment-based design approach oleh Moaz M. Abdou, Dewen Dong, Paul M. O'Neill, Eric Amigues, Magdalini Matziari

    Diterbitkan 2023-02-01
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  6. 6
    Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis

    Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis oleh Kangsa Amporndanai, Michael Rogers, Seiji Watanabe, Koji Yamanaka, Paul M. O'Neill, S. Samar Hasnain

    Diterbitkan 2020-09-01
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  7. 7
    Methyl 3-(4-hydroxyphenyl)propionate

    Methyl 3-(4-hydroxyphenyl)propionate oleh Moaz M. Abdou, Magdalini Matziari, Paul M. O'Neill, Eric Amigues, Ruixue Zhou, Ruiyao Wang, Basem F. Ali

    Diterbitkan 2018-11-01
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  8. 8
    Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement

    Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement oleh Seiji Watanabe, Kangsa Amporndanai, Raheela Awais, Caroline Latham, Muhammad Awais, Paul M. O’Neill, Koji Yamanaka, S. Samar Hasnain

    Diterbitkan 2024-05-01
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  9. 9
    X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery

    X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery oleh Kangsa Amporndanai, Rachel M. Johnson, Paul M. O'Neill, Colin W. G. Fishwick, Alexander H. Jamson, Shaun Rawson, Stephen P. Muench, S. Samar Hasnain, Svetlana V. Antonyuk

    Diterbitkan 2018-03-01
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  10. 10
    Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

    Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives oleh Kangsa Amporndanai, Xiaoli Meng, Weijuan Shang, Zhenmig Jin, Michael Rogers, Yao Zhao, Zihe Rao, Zhi-Jie Liu, Haitao Yang, Leike Zhang, Paul M. O’Neill, S. Samar Hasnain

    Diterbitkan 2021-05-01
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  11. 11
    α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy

    α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy oleh Shi Quan Wong, Matthew G. Pontifex, Marie M. Phelan, Chandra Pidathala, Brian C. Kraemer, Jeff W. Barclay, Neil G. Berry, Paul M. O'Neill, Robert D. Burgoyne, Alan Morgan

    Diterbitkan 2018-10-01
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  12. 12
    The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation

    The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation oleh Michael J. Capper, Gareth S. A. Wright, Letizia Barbieri, Enrico Luchinat, Eleonora Mercatelli, Luke McAlary, Justin J. Yerbury, Paul M. O’Neill, Svetlana V. Antonyuk, Lucia Banci, S. Samar Hasnain

    Diterbitkan 2018-04-01
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  13. 13
    Targeting the Ubiquinol-Reduction (Q<sub>i</sub>) Site of the Mitochondrial Cytochrome <i>bc<sub>1</sub></i> Complex for the Development of Next Generation Quinolone Antimalarials

    Targeting the Ubiquinol-Reduction (Q<sub>i</sub>) Site of the Mitochondrial Cytochrome <i>bc<sub>1</sub></i> Complex for the Development of Next Generation Quinolone Antimalarials oleh Kangsa Amporndanai, Nattapon Pinthong, Paul M. O’Neill, W. David Hong, Richard K. Amewu, Chandrakala Pidathala, Neil G. Berry, Suet C. Leung, Stephen A. Ward, Giancarlo A. Biagini, S. Samar Hasnain, Svetlana V. Antonyuk

    Diterbitkan 2022-07-01
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  14. 14
    Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform

    Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform oleh Laura-Oana Albulescu, Laura-Oana Albulescu, Adam Westhorpe, Adam Westhorpe, Rachel H. Clare, Rachel H. Clare, Christopher M. Woodley, Nivya James, Jeroen Kool, Neil G. Berry, Paul M. O’Neill, Nicholas R. Casewell, Nicholas R. Casewell

    Diterbitkan 2024-01-01
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  15. 15
    Antimalarial activity of primaquine operates via a two-step biochemical relay

    Antimalarial activity of primaquine operates via a two-step biochemical relay oleh Grazia Camarda, Piyaporn Jirawatcharadech, Richard S. Priestley, Ahmed Saif, Sandra March, Michael H. L. Wong, Suet Leung, Alex B. Miller, David A. Baker, Pietro Alano, Mark J. I. Paine, Sangeeta N. Bhatia, Paul M. O’Neill, Stephen A. Ward, Giancarlo A. Biagini

    Diterbitkan 2019-07-01
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  16. 16
    Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors

    Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors oleh Rachel H. Clare, Rachel H. Clare, Charlotte A. Dawson, Charlotte A. Dawson, Adam Westhorpe, Adam Westhorpe, Laura-Oana Albulescu, Laura-Oana Albulescu, Christopher M. Woodley, Nada Mosallam, Daniel J. W. Chong, Jeroen Kool, Neil G. Berry, Paul M. O’Neill, Nicholas R. Casewell, Nicholas R. Casewell

    Diterbitkan 2024-01-01
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  17. 17
    Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

    Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides oleh Rachel H. Clare, Catherine Bardelle, Paul Harper, W. David Hong, Ulf Börjesson, Kelly L. Johnston, Matthew Collier, Laura Myhill, Andrew Cassidy, Darren Plant, Helen Plant, Roger Clark, Darren A. N. Cook, Andrew Steven, John Archer, Paul McGillan, Sitthivut Charoensutthivarakul, Jaclyn Bibby, Raman Sharma, Gemma L. Nixon, Barton E. Slatko, Lindsey Cantin, Bo Wu, Joseph Turner, Louise Ford, Kirsty Rich, Mark Wigglesworth, Neil G. Berry, Paul M. O’Neill, Mark J. Taylor, Stephen A. Ward

    Diterbitkan 2019-01-01
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  18. 18
    A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

    A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance oleh Paul M. O’Neill, Richard K. Amewu, Susan A. Charman, Sunil Sabbani, Nina F. Gnädig, Judith Straimer, David A. Fidock, Emma R. Shore, Natalie L. Roberts, Michael H.-L. Wong, W. David Hong, Chandrakala Pidathala, Chris Riley, Ben Murphy, Ghaith Aljayyoussi, Francisco Javier Gamo, Laura Sanz, Janneth Rodrigues, Carolina Gonzalez Cortes, Esperanza Herreros, Iñigo Angulo-Barturén, María Belén Jiménez-Díaz, Santiago Ferrer Bazaga, María Santos Martínez-Martínez, Brice Campo, Raman Sharma, Eileen Ryan, David M. Shackleford, Simon Campbell, Dennis A. Smith, Grennady Wirjanata, Rintis Noviyanti, Ric N. Price, Jutta Marfurt, Michael J. Palmer, Ian M. Copple, Amy E. Mercer, Andrea Ruecker, Michael J. Delves, Robert E. Sinden, Peter Siegl, Jill Davies, Rosemary Rochford, Clemens H. M. Kocken, Anne-Marie Zeeman, Gemma L. Nixon, Giancarlo A. Biagini, Stephen A. Ward

    Diterbitkan 2017-05-01
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