Hasil Pencarian - Paul D. Upton

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  1. 1
    Targeting translational read-through of premature termination mutations in with PTC124 for pulmonary arterial hypertension

    Targeting translational read-through of premature termination mutations in with PTC124 for pulmonary arterial hypertension oleh Lu Long, Xudong Yang, Mark Southwood, Stephen Moore, Alexi Crosby, Paul D. Upton, Benjamin J. Dunmore, Nicholas W. Morrell

    Diterbitkan 2020-07-01
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  2. 2
    Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein

    Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein oleh Lidia Ruiz-Llorente, M. Cristina Vega, Francisco J. Fernández, Carmen Langa, Nicholas W. Morrell, Paul D. Upton, Carmelo Bernabeu

    Diterbitkan 2021-10-01
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  3. 3
    Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis

    Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis oleh Nicola E. Owen, Graeme J. Alexander, Sambit Sen, Katherine Bunclark, Gary Polwarth, Joanna Pepke-Zaba, Anthony P. Davenport, Nicholas, W. Morrell, Paul. D. Upton

    Diterbitkan 2020-06-01
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  4. 4
    BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.

    BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production. oleh John E S Park, Dongmin Shao, Paul D Upton, Patricia Desouza, Ian M Adcock, Rachel J Davies, Nicholas W Morrell, Mark J D Griffiths, Stephen J Wort

    Diterbitkan 2012-01-01
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  5. 5
    Correction: BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production.

    Correction: BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production. oleh John E. S. Park, Dongmin Shao, Paul D. Upton, Patricia deSouza, Ian M. Adcock, Rachel J. Davies, Nicholas W. Morrell, Mark J. D. Griffiths, Stephen J. Wort

    Diterbitkan 2013-01-01
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  6. 6
    High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells

    High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells oleh Clara Andersson-Rusch, Bin Liu, Ingrid Quist-Løkken, Paul D. Upton, Oddrun Elise Olsen, Hanne Hella, Xudong Yang, Zhen Tong, Nicholas W. Morrell, Toril Holien, Wei Li

    Diterbitkan 2023-04-01
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  7. 7
    Transcript analysis reveals a specific HOX signature associated with positional identity of human endothelial cells.

    Transcript analysis reveals a specific HOX signature associated with positional identity of human endothelial cells. oleh Mark Toshner, Benjamin J Dunmore, Eoin F McKinney, Mark Southwood, Paola Caruso, Paul D Upton, John P Waters, Mark L Ormiston, Jeremy N Skepper, Gerard Nash, Amer A Rana, Nicholas W Morrell

    Diterbitkan 2014-01-01
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  8. 8
    Reduced circulating BMP9 and pBMP10 in hospitalized COVID‐19 patients

    Reduced circulating BMP9 and pBMP10 in hospitalized COVID‐19 patients oleh Benjamin J. Dunmore, Paul D. Upton, Kate Auckland, Romit J. Samanta, CITIID‐NIHR BioResource COVID‐19 Collaboration, The EpiCov Database, Paul A. Lyons, Kenneth G. C. Smith, Stefan Gräf, Charlotte Summers, Nicholas W. Morrell

    Diterbitkan 2023-01-01
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  9. 9
    Homozygous GDF2 nonsense mutations result in a loss of circulating BMP9 and BMP10 and are associated with either PAH or an “HHT‐like” syndrome in children

    Homozygous GDF2 nonsense mutations result in a loss of circulating BMP9 and BMP10 and are associated with either PAH or an “HHT‐like” syndrome in children oleh Joshua Hodgson, Lidia Ruiz‐Llorente, Jamie McDonald, Oliver Quarrell, Kelechi Ugonna, James Bentham, Rebecca Mason, Jennifer Martin, David Moore, Katie Bergstrom, Pinar Bayrak‐Toydemir, Whitney Wooderchak‐Donahue, Nicholas W. Morrell, Robin Condliffe, Carmelo Bernabeu, Paul D. Upton

    Diterbitkan 2021-12-01
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  10. 10
    TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

    TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling oleh Liam A. Hurst, Benjamin J. Dunmore, Lu Long, Alexi Crosby, Rafia Al-Lamki, John Deighton, Mark Southwood, Xudong Yang, Marko Z. Nikolic, Blanca Herrera, Gareth J. Inman, John R. Bradley, Amer A. Rana, Paul D. Upton, Nicholas W. Morrell

    Diterbitkan 2017-01-01
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  11. 11
    An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis

    An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis oleh Alexander J. Ainscough, Timothy J. Smith, Maike Haensel, Christopher J. Rhodes, Adam Fellows, Harry J. Whitwell, Eleni Vasilaki, Kelly Gray, Adrian Freeman, Luke S. Howard, John Wharton, Benjamin Dunmore, Paul D. Upton, Martin R. Wilkins, Joshua B. Edel, Beata Wojciak-Stothard

    Diterbitkan 2022-11-01
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  12. 12
    Author Correction: Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2

    Author Correction: Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2 oleh Tatyana Novoyatleva, Nabham Rai, Baktybek Kojonazarov, Swathi Veeroju, Isabel Ben-Batalla, Paola Caruso, Mazen Shihan, Nadine Presser, Elsa Götz, Carina Lepper, Sebastian Herpel, Grégoire Manaud, Frédéric Perros, Henning Gall, Hossein Ardeschir Ghofrani, Norbert Weissmann, Friedrich Grimminger, John Wharton, Martin Wilkins, Paul D. Upton, Sonja Loges, Nicholas W. Morrell, Werner Seeger, Ralph T. Schermuly

    Diterbitkan 2022-01-01
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  13. 13
    Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2

    Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2 oleh Tatyana Novoyatleva, Nabham Rai, Baktybek Kojonazarov, Swathi Veeroju, Isabel Ben-Batalla, Paola Caruso, Mazen Shihan, Nadine Presser, Elsa Götz, Carina Lepper, Sebastian Herpel, Grégoire Manaud, Frédéric Perros, Henning Gall, Hossein Ardeschir Ghofrani, Norbert Weissmann, Friedrich Grimminger, John Wharton, Martin Wilkins, Paul D. Upton, Sonja Loges, Nicholas W. Morrell, Werner Seeger, Ralph T. Schermuly

    Diterbitkan 2021-08-01
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  14. 14
    Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

    Identification of rare sequence variation underlying heritable pulmonary arterial hypertension oleh Stefan Gräf, Matthias Haimel, Marta Bleda, Charaka Hadinnapola, Laura Southgate, Wei Li, Joshua Hodgson, Bin Liu, Richard M. Salmon, Mark Southwood, Rajiv D. Machado, Jennifer M. Martin, Carmen M. Treacy, Katherine Yates, Louise C. Daugherty, Olga Shamardina, Deborah Whitehorn, Simon Holden, Micheala Aldred, Harm J. Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A. Corris, Cesare Danesino, Mélanie Eyries, Henning Gall, Stefano Ghio, Hossein-Ardeschir Ghofrani, J. Simon R. Gibbs, Barbara Girerd, Arjan C. Houweling, Luke Howard, Marc Humbert, David G. Kiely, Gabor Kovacs, Robert V. MacKenzie Ross, Shahin Moledina, David Montani, Michael Newnham, Andrea Olschewski, Horst Olschewski, Andrew J. Peacock, Joanna Pepke-Zaba, Inga Prokopenko, Christopher J. Rhodes, Laura Scelsi, Werner Seeger, Florent Soubrier, Dan F. Stein, Jay Suntharalingam, Emilia M. Swietlik, Mark R. Toshner, David A. van Heel, Anton Vonk Noordegraaf, Quinten Waisfisz, John Wharton, Stephen J. Wort, Willem H. Ouwehand, Nicole Soranzo, Allan Lawrie, Paul D. Upton, Martin R. Wilkins, Richard C. Trembath, Nicholas W. Morrell

    Diterbitkan 2018-04-01
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