Hasil Pencarian - Paul A. M. Michels

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  1. 1
    Autophagy in Trypanosomatids

    Autophagy in Trypanosomatids oleh Paul A. M. Michels, Eva Rico, Ana Brennand

    Diterbitkan 2012-07-01
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  2. 2
    A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex.

    A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex. oleh Alena Zíková, Zdeněk Verner, Anna Nenarokova, Paul A M Michels, Julius Lukeš

    Diterbitkan 2017-12-01
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  3. 3
    Antimicrobial Peptides (AMPs): Potential Therapeutic Strategy against Trypanosomiases?

    Antimicrobial Peptides (AMPs): Potential Therapeutic Strategy against Trypanosomiases? oleh Maura Rojas-Pirela, Ulrike Kemmerling, Wilfredo Quiñones, Paul A. M. Michels, Verónica Rojas

    Diterbitkan 2023-03-01
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  4. 4
    Metabolic insights into phosphofructokinase inhibition in bloodstream-form trypanosomes

    Metabolic insights into phosphofructokinase inhibition in bloodstream-form trypanosomes oleh Zandile Nare, Tessa Moses, Karl Burgess, Karl Burgess, Achim Schnaufer, Malcolm D. Walkinshaw, Paul A. M. Michels

    Diterbitkan 2023-02-01
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  5. 5
    Structure, Properties, and Function of Glycosomes in Trypanosoma cruzi

    Structure, Properties, and Function of Glycosomes in Trypanosoma cruzi oleh Wilfredo Quiñones, Héctor Acosta, Camila Silva Gonçalves, Maria Cristina M. Motta, Melisa Gualdrón-López, Paul A. M. Michels

    Diterbitkan 2020-01-01
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  6. 6
    The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids

    The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids oleh Letícia Marchese, Janaina de Freitas Nascimento, Flávia Silva Damasceno, Frédéric Bringaud, Paul A. M. Michels, Ariel Mariano Silber

    Diterbitkan 2018-04-01
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  7. 7
    ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei.

    ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei. oleh Ana Brennand, Eva Rico, Daniel J Rigden, Patrick Van Der Smissen, Pierre J Courtoy, Paul A M Michels

    Diterbitkan 2015-01-01
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  8. 8
    Channel-forming activities in the glycosomal fraction from the bloodstream form of Trypanosoma brucei.

    Channel-forming activities in the glycosomal fraction from the bloodstream form of Trypanosoma brucei. oleh Melisa Gualdron-López, Miia H Vapola, Ilkka J Miinalainen, J Kalervo Hiltunen, Paul A M Michels, Vasily D Antonenkov

    Diterbitkan 2012-01-01
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  9. 9
    Structures of pyruvate kinases display evolutionarily divergent allosteric strategies

    Structures of pyruvate kinases display evolutionarily divergent allosteric strategies oleh Hugh P. Morgan, Wenhe Zhong, Iain W. McNae, Paul A. M. Michels, Linda A. Fothergill-Gilmore, Malcolm D. Walkinshaw

    Diterbitkan 2014-01-01
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  10. 10
    Delineating transitions during the evolution of specialised peroxisomes: Glycosome formation in kinetoplastid and diplonemid protists

    Delineating transitions during the evolution of specialised peroxisomes: Glycosome formation in kinetoplastid and diplonemid protists oleh Diego Andrade-Alviárez, Alejandro D. Bonive-Boscan, Ana J. Cáceres, Wilfredo Quiñones, Melisa Gualdrón-López, Michael L. Ginger, Paul A. M. Michels

    Diterbitkan 2022-09-01
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  11. 11
    Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target.

    Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. oleh Andrés Alloatti, Shreedhara Gupta, Melisa Gualdrón-López, Mariana Igoillo-Esteve, Paul A Nguewa, Gladys Deumer, Pierre Wallemacq, Silvia G Altabe, Paul A M Michels, Antonio D Uttaro

    Diterbitkan 2010-12-01
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  12. 12
    Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity

    Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity oleh Zabdi González-Chávez, Citlali Vázquez, Marlen Mejia-Tlachi, Claudia Márquez-Dueñas, Rebeca Manning-Cela, Rusely Encalada, Sara Rodríguez-Enríquez, Paul A.M. Michels, Rafael Moreno-Sánchez, Emma Saavedra

    Diterbitkan 2019-09-01
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  13. 13
    Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism.

    Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism. oleh Simone Pieretti, Jurgen R Haanstra, Muriel Mazet, Remo Perozzo, Christian Bergamini, Federica Prati, Romana Fato, Giorgio Lenaz, Giovanni Capranico, Reto Brun, Barbara M Bakker, Paul A M Michels, Leonardo Scapozza, Maria Laura Bolognesi, Andrea Cavalli

    Diterbitkan 2013-01-01
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  14. 14
    How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell.

    How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell. oleh Janaina F Nascimento, Rodolpho O O Souza, Mayke B Alencar, Sabrina Marsiccobetre, Ana M Murillo, Flávia S Damasceno, Richard B M M Girard, Letícia Marchese, Luis A Luévano-Martinez, Renan W Achjian, Jurgen R Haanstra, Paul A M Michels, Ariel M Silber

    Diterbitkan 2023-07-01
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  15. 15
    Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

    Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice oleh Iain W. McNae, James Kinkead, Divya Malik, Li-Hsuan Yen, Martin K. Walker, Chris Swain, Scott P. Webster, Nick Gray, Peter M. Fernandes, Elmarie Myburgh, Elizabeth A. Blackburn, Ryan Ritchie, Carol Austin, Martin A. Wear, Adrian J. Highton, Andrew J. Keats, Antonio Vong, Jacqueline Dornan, Jeremy C. Mottram, Paul A. M. Michels, Simon Pettit, Malcolm D. Walkinshaw

    Diterbitkan 2021-02-01
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  16. 16
    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery oleh Pasquale Linciano, Alice Dawson, Ina Pöhner, David M. Costa, Monica S. Sá, Anabela Cordeiro-da-Silva, Rosaria Luciani, Sheraz Gul, Gesa Witt, Bernhard Ellinger, Maria Kuzikov, Philip Gribbon, Jeanette Reinshagen, Markus Wolf, Birte Behrens, Véronique Hannaert, Paul A. M. Michels, Erika Nerini, Cecilia Pozzi, Flavio di Pisa, Giacomo Landi, Nuno Santarem, Stefania Ferrari, Puneet Saxena, Sandra Lazzari, Giuseppe Cannazza, Lucio H. Freitas-Junior, Carolina B. Moraes, Bruno S. Pascoalino, Laura M. Alcântara, Claudia P. Bertolacini, Vanessa Fontana, Ulrike Wittig, Wolfgang Müller, Rebecca C. Wade, William N. Hunter, Stefano Mangani, Luca Costantino, Maria P. Costi

    Diterbitkan 2017-09-01
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