Hasil Pencarian - Panagis Filippakopoulos

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  1. 1
    Editorial: Structural Studies of Protein Complexes in Signaling Pathways

    Editorial: Structural Studies of Protein Complexes in Signaling Pathways oleh Filippo Prischi, Panagis Filippakopoulos

    Diterbitkan 2021-04-01
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  2. 2
    BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy

    BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy oleh Marco Segatto, Roberta Szokoll, Raffaella Fittipaldi, Cinzia Bottino, Lorenzo Nevi, Kamel Mamchaoui, Panagis Filippakopoulos, Giuseppina Caretti

    Diterbitkan 2020-11-01
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  3. 3
    Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12

    Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12 oleh Zhuoyao Chen, Gregory A. Wasney, Sarah Picaud, Panagis Filippakopoulos, Masoud Vedadi, Vincenzo D'Angiolella, Alex N. Bullock

    Diterbitkan 2020-06-01
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  4. 4
    Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3

    Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3 oleh Martin Schröder, Panagis Filippakopoulos, Martin P. Schwalm, Carla A. Ferrer, David H. Drewry, Stefan Knapp, Apirat Chaikuad

    Diterbitkan 2020-10-01
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  5. 5
    Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function

    Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function oleh Adam P. Cribbs, Panagis Filippakopoulos, Martin Philpott, Graham Wells, Henry Penn, Henrik Oerum, Viia Valge-Archer, Marc Feldmann, Udo Oppermann, Udo Oppermann, Udo Oppermann

    Diterbitkan 2021-02-01
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  6. 6
    A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex

    A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex oleh Chiara Marabelli, Biagina Marrocco, Simona Pilotto, Sagar Chittori, Sarah Picaud, Sara Marchese, Giuseppe Ciossani, Federico Forneris, Panagis Filippakopoulos, Guy Schoehn, Daniela Rhodes, Sriram Subramaniam, Andrea Mattevi

    Diterbitkan 2019-04-01
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  7. 7
    A TFEB nuclear export signal integrates amino acid supply and glucose availability

    A TFEB nuclear export signal integrates amino acid supply and glucose availability oleh Linxin Li, Hans J. Friedrichsen, Sarah Andrews, Sarah Picaud, Laurent Volpon, Kaochin Ngeow, Georgina Berridge, Roman Fischer, Katherine L. B. Borden, Panagis Filippakopoulos, Colin R. Goding

    Diterbitkan 2018-07-01
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  8. 8
    BET inhibition disrupts transcription but retains enhancer-promoter contact

    BET inhibition disrupts transcription but retains enhancer-promoter contact oleh Nicholas T. Crump, Erica Ballabio, Laura Godfrey, Ross Thorne, Emmanouela Repapi, Jon Kerry, Marta Tapia, Peng Hua, Christoffer Lagerholm, Panagis Filippakopoulos, James O. J. Davies, Thomas A. Milne

    Diterbitkan 2021-01-01
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  9. 9
    The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.

    The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif. oleh Petra Lukacik, C David Owen, Gemma Harris, Jani Reddy Bolla, Sarah Picaud, Irfan Alibay, Joanne E Nettleship, Louise E Bird, Raymond J Owens, Philip C Biggin, Panagis Filippakopoulos, Carol V Robinson, Martin A Walsh

    Diterbitkan 2021-01-01
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  10. 10
    The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif

    The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif oleh Petra Lukacik, C. David Owen, Gemma Harris, Jani Reddy Bolla, Sarah Picaud, Irfan Alibay, Joanne E. Nettleship, Louise E. Bird, Raymond J. Owens, Philip C. Biggin, Panagis Filippakopoulos, Carol V. Robinson, Martin A. Walsh

    Diterbitkan 2021-01-01
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  11. 11
    Acetylation reprograms MITF target selectivity and residence time

    Acetylation reprograms MITF target selectivity and residence time oleh Pakavarin Louphrasitthiphol, Alessia Loffreda, Vivian Pogenberg, Sarah Picaud, Alexander Schepsky, Hans Friedrichsen, Zhiqiang Zeng, Anahita Lashgari, Benjamin Thomas, E. Elizabeth Patton, Matthias Wilmanns, Panagis Filippakopoulos, Jean-Philippe Lambert, Eiríkur Steingrímsson, Davide Mazza, Colin R. Goding

    Diterbitkan 2023-09-01
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  12. 12
    Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival

    Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival oleh Marco Segatto, Raffaella Fittipaldi, Fabrizio Pin, Roberta Sartori, Kyung Dae Ko, Hossein Zare, Claudio Fenizia, Gianpietro Zanchettin, Elisa Sefora Pierobon, Shinji Hatakeyama, Cosimo Sperti, Stefano Merigliano, Marco Sandri, Panagis Filippakopoulos, Paola Costelli, Vittorio Sartorelli, Giuseppina Caretti

    Diterbitkan 2017-11-01
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  13. 13
    A chemical toolbox for the study of bromodomains and epigenetic signaling

    A chemical toolbox for the study of bromodomains and epigenetic signaling oleh Qin Wu, David Heidenreich, Stanley Zhou, Suzanne Ackloo, Andreas Krämer, Kiran Nakka, Evelyne Lima-Fernandes, Genevieve Deblois, Shili Duan, Ravi N. Vellanki, Fengling Li, Masoud Vedadi, Jeffrey Dilworth, Mathieu Lupien, Paul E. Brennan, Cheryl H. Arrowsmith, Susanne Müller, Oleg Fedorov, Panagis Filippakopoulos, Stefan Knapp

    Diterbitkan 2019-04-01
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  14. 14
    Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells

    Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells oleh Hitoshi Shiota, Sophie Barral, Thierry Buchou, Minjia Tan, Yohann Couté, Guillaume Charbonnier, Nicolas Reynoird, Fayçal Boussouar, Matthieu Gérard, Mingrui Zhu, Lisa Bargier, Denis Puthier, Florent Chuffart, Ekaterina Bourova-Flin, Sarah Picaud, Panagis Filippakopoulos, Afsaneh Goudarzi, Ziad Ibrahim, Daniel Panne, Sophie Rousseaux, Yingming Zhao, Saadi Khochbin

    Diterbitkan 2018-09-01
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  15. 15
    Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression

    Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression oleh João Conde, Ruth A. Pumroy, Charlotte Baker, Tiago Rodrigues, Ana Guerreiro, Bárbara B. Sousa, Marta C. Marques, Bernardo P. de Almeida, Sohyon Lee, Elvira P. Leites, Daniel Picard, Amrita Samanta, Sandra H. Vaz, Florian Sieglitz, Maike Langini, Marc Remke, Rafael Roque, Tobias Weiss, Michael Weller, Yuhang Liu, Seungil Han, Francisco Corzana, Vanessa A. Morais, Cláudia C. Faria, Tânia Carvalho, Panagis Filippakopoulos, Berend Snijder, Nuno L. Barbosa-Morais, Vera Y. Moiseenkova-Bell, Gonçalo J. L. Bernardes

    Diterbitkan 2021-04-01
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