Hasil Pencarian - P Hande Ozdinler

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  1. 1
    Mitoautophagy: A Unique Self-Destructive Path Mitochondria of Upper Motor Neurons With TDP-43 Pathology Take, Very Early in ALS

    Mitoautophagy: A Unique Self-Destructive Path Mitochondria of Upper Motor Neurons With TDP-43 Pathology Take, Very Early in ALS oleh Mukesh Gautam, Mukesh Gautam, Edward F. Xie, Nuran Kocak, P. Hande Ozdinler, P. Hande Ozdinler, P. Hande Ozdinler, P. Hande Ozdinler

    Diterbitkan 2019-11-01
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  2. 2
    Complexity of Generating Mouse Models to Study the Upper Motor Neurons: Let Us Shift Focus from Mice to Neurons

    Complexity of Generating Mouse Models to Study the Upper Motor Neurons: Let Us Shift Focus from Mice to Neurons oleh Baris Genc, Oge Gozutok, P. Hande Ozdinler

    Diterbitkan 2019-08-01
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  3. 3
    Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS

    Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS oleh Oge Gozutok, Benjamin Ryan Helmold, P. Hande Ozdinler

    Diterbitkan 2021-04-01
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  4. 4
    The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord

    The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord oleh Baris Genc, Oge Gozutok, Nuran Kocak, P. Hande Ozdinler

    Diterbitkan 2020-02-01
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  5. 5
    Mitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD+ balance as a therapeutic strategy

    Mitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD+ balance as a therapeutic strategy oleh Mukesh Gautam, Aksu Gunay, Navdeep S. Chandel, P. Hande Ozdinler

    Diterbitkan 2022-03-01
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  6. 6
    Spastin and alsin protein interactome analyses begin to reveal key canonical pathways and suggest novel druggable targets

    Spastin and alsin protein interactome analyses begin to reveal key canonical pathways and suggest novel druggable targets oleh Benjamin R. Helmold, Angela Ahrens, Zachary Fitzgerald, P. Hande Ozdinler

    Diterbitkan 2025-03-01
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  7. 7
    A chemoattractant role for NT-3 in proprioceptive axon guidance.

    A chemoattractant role for NT-3 in proprioceptive axon guidance. oleh Bariş Genç, P Hande Ozdinler, April E Mendoza, Reha S Erzurumlu

    Diterbitkan 2004-12-01
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  8. 8
    AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS

    AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS oleh Javier H. Jara, Stephanie R. Villa, Nabil A. Khan, Martha C. Bohn, P. Hande Özdinler

    Diterbitkan 2012-08-01
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  9. 9
    MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

    MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology oleh Javier H. Jara, Mukesh Gautam, Nuran Kocak, Edward F. Xie, Qinwen Mao, Eileen H. Bigio, P. Hande Özdinler

    Diterbitkan 2019-10-01
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  10. 10
    NU-9 improves health of hSOD1G93A mouse upper motor neurons in vitro, especially in combination with riluzole or edaravone

    NU-9 improves health of hSOD1G93A mouse upper motor neurons in vitro, especially in combination with riluzole or edaravone oleh Barış Genç, Mukesh Gautam, Benjamin R. Helmold, Nuran Koçak, Aksu Günay, Gashaw M. Goshu, Richard B. Silverman, P. Hande Ozdinler

    Diterbitkan 2022-03-01
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  11. 11
    2-Year-Old and 3-Year-Old Italian ALS Patients with Novel <i>ALS2</i> Mutations: Identification of Key Metabolites in Their Serum and Plasma

    2-Year-Old and 3-Year-Old Italian ALS Patients with Novel <i>ALS2</i> Mutations: Identification of Key Metabolites in Their Serum and Plasma oleh Mukesh Gautam, Renata Del Carratore, Benjamin Helmold, Alessandra Tessa, Oge Gozutok, Navdeep Chandel, Halil Idrisoglu, Paolo Bongioanni, Roberta Battini, P.Hande Ozdinler

    Diterbitkan 2022-02-01
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  12. 12
    Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP‐43 pathology

    Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP‐43 pathology oleh Barış Genç, Mukesh Gautam, Öge Gözütok, Ina Dervishi, Santana Sanchez, Gashaw M. Goshu, Nuran Koçak, Edward Xie, Richard B. Silverman, P. Hande Özdinler

    Diterbitkan 2021-02-01
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  13. 13
    The Electrophysiological Determinants of Corticospinal Motor Neuron Vulnerability in ALS

    The Electrophysiological Determinants of Corticospinal Motor Neuron Vulnerability in ALS oleh Javier H. Jara, Patrick L. Sheets, Maximiliano José Nigro, Mina Perić, Carolyn Brooks, Daniel B. Heller, Marco Martina, Pavle R. Andjus, P. Hande Ozdinler

    Diterbitkan 2020-05-01
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  14. 14
    Visualization of Sensory Neurons and Their Projections in an Upper Motor Neuron Reporter Line.

    Visualization of Sensory Neurons and Their Projections in an Upper Motor Neuron Reporter Line. oleh Barış Genç, Amiko Krisa Bunag Lagrimas, Pınar Kuru, Robert Hess, Michael William Tu, Daniela Maria Menichella, Richard J Miller, Amy S Paller, P Hande Özdinler

    Diterbitkan 2015-01-01
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  15. 15
    Evidence for an early innate immune response in the motor cortex of ALS

    Evidence for an early innate immune response in the motor cortex of ALS oleh Javier H. Jara, Barış Genç, Macdonell J. Stanford, Peter Pytel, Raymond P. Roos, Sandra Weintraub, M. Marsel Mesulam, Eileen H. Bigio, Richard J. Miller, P. Hande Özdinler

    Diterbitkan 2017-06-01
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  16. 16
    An autism-associated variant of Epac2 reveals a role for Ras/Epac2 signaling in controlling basal dendrite maintenance in mice.

    An autism-associated variant of Epac2 reveals a role for Ras/Epac2 signaling in controlling basal dendrite maintenance in mice. oleh Deepak P Srivastava, Kevin M Woolfrey, Kelly A Jones, Charles T Anderson, Katharine R Smith, Theron A Russell, Hyerin Lee, Marina V Yasvoina, David L Wokosin, P Hande Ozdinler, Gordon M G Shepherd, Peter Penzes

    Diterbitkan 2012-01-01
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  17. 17
    SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function

    SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function oleh Mukesh Gautam, Barış Genç, Benjamin Helmold, Angela Ahrens, Janis Kuka, Marina Makrecka-Kuka, Aksu Günay, Nuran Koçak, Izaak R. Aguilar-Wickings, Dennis Keefe, Guozhu Zheng, Suchitra Swaminathan, Martin Redmon, Hatim A. Zariwala, P. Hande Özdinler

    Diterbitkan 2023-03-01
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