Hasil Pencarian - Ornit Chiba-Falek

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  1. 1
    Bioinformatics pipeline to guide late‐onset Alzheimer's disease (LOAD) post‐GWAS studies: Prioritizing transcription regulatory variants within LOAD‐associated regions

    Bioinformatics pipeline to guide late‐onset Alzheimer's disease (LOAD) post‐GWAS studies: Prioritizing transcription regulatory variants within LOAD‐associated regions oleh Michael W. Lutz, Ornit Chiba‐Falek

    Diterbitkan 2022-01-01
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  2. 2
    Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer’s Disease Based on Major Depressive Disorder Risk Variants

    Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer’s Disease Based on Major Depressive Disorder Risk Variants oleh Suraj Upadhya, Hongliang Liu, Hongliang Liu, Sheng Luo, Michael W. Lutz, Ornit Chiba-Falek, Ornit Chiba-Falek

    Diterbitkan 2022-03-01
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  3. 3
    Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders

    Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders oleh Julia Gamache, Young Yun, Ornit Chiba-Falek

    Diterbitkan 2020-08-01
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  4. 4
    Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes.

    Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes. oleh Julio Barrera, Shobana Subramanian, Ornit Chiba-Falek

    Diterbitkan 2018-01-01
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  5. 5
    Neuronal-type-specific epigenome editing to decrease SNCA expression: Implications for precision medicine in synucleinopathies

    Neuronal-type-specific epigenome editing to decrease SNCA expression: Implications for precision medicine in synucleinopathies oleh Zhiguo Sun, Boris Kantor, Ornit Chiba-Falek

    Diterbitkan 2024-03-01
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  6. 6
    <i>APOE</i>: The New Frontier in the Development of a Therapeutic Target towards Precision Medicine in Late-Onset Alzheimer’s

    <i>APOE</i>: The New Frontier in the Development of a Therapeutic Target towards Precision Medicine in Late-Onset Alzheimer’s oleh Anna Yang, Boris Kantor, Ornit Chiba-Falek

    Diterbitkan 2021-01-01
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  7. 7
    Gene expression Analysis of Neurons and Astrocytes Isolated by Laser Capture Microdissection from Frozen Human Brain Tissues.

    Gene expression Analysis of Neurons and Astrocytes Isolated by Laser Capture Microdissection from Frozen Human Brain Tissues. oleh Lidia Tagliafierro, Lidia Tagliafierro, Kirsten Bonawitz, Kirsten Bonawitz, Omolara Chinue Glenn, Omolara Chinue Glenn, Ornit Chiba-Falek, Ornit Chiba-Falek

    Diterbitkan 2016-08-01
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  8. 8
    Interpreting Gene Expression Effects of Disease-Associated Variants: A Lesson from SNCA rs356168

    Interpreting Gene Expression Effects of Disease-Associated Variants: A Lesson from SNCA rs356168 oleh Omolara-Chinue Glenn, Omolara-Chinue Glenn, Lidia Tagliafierro, Lidia Tagliafierro, Thomas G. Beach, Randy L. Woltjer, Ornit Chiba-Falek, Ornit Chiba-Falek

    Diterbitkan 2017-09-01
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  9. 9
    Differential Gene Expression and DNA Methylation in the Risk of Depression in LOAD Patients

    Differential Gene Expression and DNA Methylation in the Risk of Depression in LOAD Patients oleh Suraj Upadhya, Daniel Gingerich, Michael William Lutz, Ornit Chiba-Falek

    Diterbitkan 2022-11-01
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  10. 10
    The Landscape of SNCA Transcripts Across Synucleinopathies: New Insights From Long Reads Sequencing Analysis

    The Landscape of SNCA Transcripts Across Synucleinopathies: New Insights From Long Reads Sequencing Analysis oleh Elizabeth Tseng, William J. Rowell, Omolara-Chinue Glenn, Omolara-Chinue Glenn, Ting Hon, Julio Barrera, Julio Barrera, Steve Kujawa, Ornit Chiba-Falek, Ornit Chiba-Falek

    Diterbitkan 2019-07-01
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  11. 11
    Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases

    Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases oleh Joseph Edward Rittiner, Joseph Edward Rittiner, Joseph Edward Rittiner, Malik Moncalvo, Malik Moncalvo, Malik Moncalvo, Ornit Chiba-Falek, Ornit Chiba-Falek, Boris Kantor, Boris Kantor, Boris Kantor

    Diterbitkan 2020-08-01
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  12. 12
    Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains

    Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains oleh Jeffrey Gu, Jeffrey Gu, Julio Barrera, Julio Barrera, Young Yun, Young Yun, Susan K. Murphy, Thomas G. Beach, Randy L. Woltjer, Geidy E. Serrano, Boris Kantor, Boris Kantor, Ornit Chiba-Falek, Ornit Chiba-Falek

    Diterbitkan 2021-04-01
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  13. 13
    The therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders

    The therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders oleh Boris Kantor, Bernadette O’Donovan, Joseph Rittiner, Dellila Hodgson, Nicholas Lindner, Sophia Guerrero, Wendy Dong, Austin Zhang, Ornit Chiba-Falek

    Diterbitkan 2024-08-01
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  14. 14
    Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains

    Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains oleh Julia Gamache, Daniel Gingerich, E. Keats Shwab, Julio Barrera, Melanie E. Garrett, Cordelia Hume, Gregory E. Crawford, Allison E. Ashley-Koch, Ornit Chiba-Falek

    Diterbitkan 2023-10-01
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  15. 15
    Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues.

    Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues. oleh Colton Linnertz, Laura Saucier, Dongliang Ge, Kenneth D Cronin, James R Burke, Jeffrey N Browndyke, Christine M Hulette, Kathleen A Welsh-Bohmer, Ornit Chiba-Falek

    Diterbitkan 2009-10-01
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  16. 16
    Single-nucleus multi-omics of Parkinson’s disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks

    Single-nucleus multi-omics of Parkinson’s disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks oleh E. Keats Shwab, Daniel C. Gingerich, Zhaohui Man, Julia Gamache, Melanie E. Garrett, Gregory E. Crawford, Allison E. Ashley-Koch, Geidy E. Serrano, Thomas G. Beach, Michael W. Lutz, Ornit Chiba-Falek

    Diterbitkan 2024-07-01
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  17. 17
    Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains

    Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains oleh Julio Barrera, Lingyun Song, Julia E. Gamache, Melanie E. Garrett, Alexias Safi, Young Yun, Ivana Premasinghe, Daniel Sprague, Danielle Chipman, Jeffrey Li, Hélène Fradin, Karen Soldano, Raluca Gordân, Allison E. Ashley-Koch, Gregory E. Crawford, Ornit Chiba-Falek

    Diterbitkan 2021-08-01
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  18. 18
    Characterization of the poly-T variant in the TOMM40 gene in diverse populations.

    Characterization of the poly-T variant in the TOMM40 gene in diverse populations. oleh Colton Linnertz, Ann M Saunders, Michael W Lutz, Donna M Crenshaw, Iris Grossman, Daniel K Burns, Keith E Whitfield, Michael A Hauser, Jeanette J McCarthy, Megan Ulmer, Rand Allingham, Kathleen A Welsh-Bohmer, Allen D Roses, Ornit Chiba-Falek

    Diterbitkan 2012-01-01
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  19. 19
    Infection and inflammation: New perspectives on Alzheimer's disease

    Infection and inflammation: New perspectives on Alzheimer's disease oleh Heather E. Whitson, Carol Colton, Joseph El Khoury, David Gate, Alison Goate, Michael T. Heneka, Rima Kaddurah-Daouk, Robyn S. Klein, Mari L. Shinohara, Sangram Sisodia, Serena S. Spudich, Beth Stevens, Rudolph Tanzi, Jenny P. Ting, Gwenn Garden, Alison Aiello, Ornit Chiba-Falek, Joseph Heitman, Kim G. Johnson, Micah Luftig, Ashley Moseman, Jonathan Rawls, Mari L. Shinohara, Ronald Swanstrom, Niccolo Terrando

    Diterbitkan 2022-07-01
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  20. 20
    Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets

    Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets oleh Max Lam, Joey W. Trampush, Jin Yu, Emma Knowles, Gail Davies, David C. Liewald, John M. Starr, Srdjan Djurovic, Ingrid Melle, Kjetil Sundet, Andrea Christoforou, Ivar Reinvang, Pamela DeRosse, Astri J. Lundervold, Vidar M. Steen, Thomas Espeseth, Katri Räikkönen, Elisabeth Widen, Aarno Palotie, Johan G. Eriksson, Ina Giegling, Bettina Konte, Panos Roussos, Stella Giakoumaki, Katherine E. Burdick, Antony Payton, William Ollier, Ornit Chiba-Falek, Deborah K. Attix, Anna C. Need, Elizabeth T. Cirulli, Aristotle N. Voineskos, Nikos C. Stefanis, Dimitrios Avramopoulos, Alex Hatzimanolis, Dan E. Arking, Nikolaos Smyrnis, Robert M. Bilder, Nelson A. Freimer, Tyrone D. Cannon, Edythe London, Russell A. Poldrack, Fred W. Sabb, Eliza Congdon, Emily Drabant Conley, Matthew A. Scult, Dwight Dickinson, Richard E. Straub, Gary Donohoe, Derek Morris, Aiden Corvin, Michael Gill, Ahmad R. Hariri, Daniel R. Weinberger, Neil Pendleton, Panos Bitsios, Dan Rujescu, Jari Lahti, Stephanie Le Hellard, Matthew C. Keller, Ole A. Andreassen, Ian J. Deary, David C. Glahn, Anil K. Malhotra, Todd Lencz

    Diterbitkan 2017-11-01
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