Hasil Pencarian - Nobuhiko Tokuriki

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  1. 1
    Pervasive epistasis exposes intramolecular networks in adaptive enzyme evolution

    Pervasive epistasis exposes intramolecular networks in adaptive enzyme evolution oleh Karol Buda, Charlotte M. Miton, Nobuhiko Tokuriki

    Diterbitkan 2023-12-01
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  2. 2
    Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase

    Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase oleh John Z Chen, Douglas M Fowler, Nobuhiko Tokuriki

    Diterbitkan 2020-06-01
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  3. 3
    Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity.

    Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity. oleh Miriam Kaltenbach, Stephane Emond, Florian Hollfelder, Nobuhiko Tokuriki

    Diterbitkan 2016-10-01
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  4. 4
    How protein stability and new functions trade off.

    How protein stability and new functions trade off. oleh Nobuhiko Tokuriki, Francois Stricher, Luis Serrano, Dan S Tawfik

    Diterbitkan 2008-02-01
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  5. 5
    The adaptive landscape of a metallo-enzyme is shaped by environment-dependent epistasis

    The adaptive landscape of a metallo-enzyme is shaped by environment-dependent epistasis oleh Dave W. Anderson, Florian Baier, Gloria Yang, Nobuhiko Tokuriki

    Diterbitkan 2021-06-01
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  6. 6
    Rapid evolutionary change in trait correlations of single proteins

    Rapid evolutionary change in trait correlations of single proteins oleh Pouria Dasmeh, Jia Zheng, Ayşe Nisan Erdoğan, Nobuhiko Tokuriki, Andreas Wagner

    Diterbitkan 2024-04-01
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  7. 7
    Reverse evolution leads to genotypic incompatibility despite functional and active site convergence

    Reverse evolution leads to genotypic incompatibility despite functional and active site convergence oleh Miriam Kaltenbach, Colin J Jackson, Eleanor C Campbell, Florian Hollfelder, Nobuhiko Tokuriki

    Diterbitkan 2015-08-01
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  8. 8
    Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis

    Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis oleh Stephane Emond, Maya Petek, Emily J. Kay, Brennen Heames, Sean R. A. Devenish, Nobuhiko Tokuriki, Florian Hollfelder

    Diterbitkan 2020-07-01
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  9. 9
    Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes

    Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes oleh Florian Baier, Nansook Hong, Gloria Yang, Anna Pabis, Charlotte M Miton, Alexandre Barrozo, Paul D Carr, Shina CL Kamerlin, Colin J Jackson, Nobuhiko Tokuriki

    Diterbitkan 2019-02-01
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  10. 10
    Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections

    Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections oleh Janine N. Copp, Daniel Pletzer, Alistair S. Brown, Joris Van der Heijden, Charlotte M. Miton, Rebecca J. Edgar, Michelle H. Rich, Rory F. Little, Elsie M. Williams, Robert E. W. Hancock, Nobuhiko Tokuriki, David F. Ackerley

    Diterbitkan 2020-10-01
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  11. 11
    A revised biosynthetic pathway for the cofactor F420 in prokaryotes

    A revised biosynthetic pathway for the cofactor F420 in prokaryotes oleh Ghader Bashiri, James Antoney, Ehab N. M. Jirgis, Mihir V. Shah, Blair Ney, Janine Copp, Stephanie M. Stuteley, Sreevalsan Sreebhavan, Brian Palmer, Martin Middleditch, Nobuhiko Tokuriki, Chris Greening, Colin Scott, Edward N. Baker, Colin J. Jackson

    Diterbitkan 2019-04-01
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