Hasil Pencarian - Nicholas S Caron

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  1. 1
    Using FLIM-FRET to measure conformational changes of transglutaminase type 2 in live cells.

    Using FLIM-FRET to measure conformational changes of transglutaminase type 2 in live cells. oleh Nicholas S Caron, Lise N Munsie, Jeffrey W Keillor, Ray Truant

    Diterbitkan 2012-01-01
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  2. 2
    Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline

    Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline oleh Siddharth Nath, Nicholas S. Caron, Linda May, Oxana B. Gluscencova, Jill Kolesar, Lauren Brady, Brett A. Kaufman, Gabrielle L. Boulianne, Amadeo R. Rodriguez, Mark A. Tarnopolsky, Ray Truant

    Diterbitkan 2022-04-01
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  3. 3
    Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity

    Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity oleh Fanny L. Lemarié, Nicholas S. Caron, Shaun S. Sanders, Mandi E. Schmidt, Yen T.N. Nguyen, Seunghyun Ko, Xiaohong Xu, Mahmoud A. Pouladi, Dale D.O. Martin, Michael R. Hayden

    Diterbitkan 2021-10-01
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  4. 4
    DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease

    DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease oleh Mandi E. Schmidt, Nicholas S. Caron, Amirah E. Aly, Fanny L. Lemarié, Louisa Dal Cengio, Yun Ko, Nikola Lazic, Lisa Anderson, Betty Nguyen, Lynn A. Raymond, Michael R. Hayden

    Diterbitkan 2020-11-01
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  5. 5
    Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice

    Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice oleh Nicholas S. Caron, Raul Banos, Amirah E. Aly, Yuanyun Xie, Seunghyun Ko, Nalini Potluri, Christine Anderson, Hailey Findlay Black, Lisa M. Anderson, Benjamin Gordon, Amber L. Southwell, Michael R. Hayden

    Diterbitkan 2022-05-01
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  6. 6
    Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models

    Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models oleh Paweł Joachimiak, Adam Ciesiołka, Emilia Kozłowska, Paweł M. Świtoński, Grzegorz Figura, Agata Ciołak, Grażyna Adamek, Magdalena Surdyka, Żaneta Kalinowska-Pośka, Maciej Figiel, Nicholas S. Caron, Michael R. Hayden, Agnieszka Fiszer

    Diterbitkan 2023-02-01
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  7. 7
    Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

    Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease oleh Dagmar E. Ehrnhoefer, Dale D. O. Martin, Mandi E. Schmidt, Xiaofan Qiu, Safia Ladha, Nicholas S. Caron, Niels H. Skotte, Yen T. N. Nguyen, Kuljeet Vaid, Amber L. Southwell, Sabine Engemann, Sonia Franciosi, Michael R. Hayden

    Diterbitkan 2018-03-01
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  8. 8
    The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons

    The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons oleh Emily Machiela, Ritika Jeloka, Nicholas S. Caron, Shagun Mehta, Mandi E. Schmidt, Helen J. E. Baddeley, Colton M. Tom, Nalini Polturi, Yuanyun Xie, Virginia B. Mattis, Michael R. Hayden, Amber L. Southwell, Amber L. Southwell

    Diterbitkan 2020-09-01
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  9. 9
    Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington’s disease mice

    Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington’s disease mice oleh Nicholas S. Caron, Lauren M. Byrne, Fanny L. Lemarié, Jeffrey N. Bone, Amirah E.-E. Aly, Seunghyun Ko, Christine Anderson, Lorenzo L. Casal, Austin M. Hill, David J. Hawellek, Peter McColgan, Edward J. Wild, Blair R. Leavitt, Michael R. Hayden

    Diterbitkan 2024-10-01
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