Hasil Pencarian - Nicholas Mcgranahan

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  1. 1
    Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution

    Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution oleh Kerstin Thol, Piotr Pawlik, Nicholas McGranahan

    Diterbitkan 2022-12-01
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  2. 2
    Germline ancestry influences the evolutionary disease course in lung adenocarcinomas

    Germline ancestry influences the evolutionary disease course in lung adenocarcinomas oleh Alina Schenk, Saioa López, Maik Kschischo, Nicholas McGranahan

    Diterbitkan 2020-08-01
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  3. 3
    Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing

    Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing oleh Sijia Cui, Nicholas McGranahan, Jing Gao, Peng Chen, Wei Jiang, Lingrong Yang, Li Ma, Junfang Liao, Tian Xie, Congying Xie, Tariq Enver, Shixiu Wu

    Diterbitkan 2023-02-01
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  4. 4
    Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution

    Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution oleh Michelle Dietzen, Haoran Zhai, Olivia Lucas, Oriol Pich, Christopher Barrington, Wei-Ting Lu, Sophia Ward, Yanping Guo, Robert E. Hynds, Simone Zaccaria, Charles Swanton, Nicholas McGranahan, Nnennaya Kanu

    Diterbitkan 2024-07-01
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  5. 5
    Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer

    Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer oleh David R. Pearce, David R. Pearce, Ayse U. Akarca, Roel P. H. De Maeyer, Emily Kostina, Ariana Huebner, Ariana Huebner, Ariana Huebner, Monica Sivakumar, Monica Sivakumar, Takahiro Karasaki, Kavina Shah, Sam M. Janes, Nicholas McGranahan, Nicholas McGranahan, Venkat Reddy, Arne N. Akbar, David A. Moore, David A. Moore, Teresa Marafioti, Charles Swanton, Charles Swanton, Robert E. Hynds, Robert E. Hynds, Robert E. Hynds

    Diterbitkan 2023-06-01
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  6. 6
    Multimodal analysis unveils tumor microenvironment heterogeneity linked to immune activity and evasion

    Multimodal analysis unveils tumor microenvironment heterogeneity linked to immune activity and evasion oleh Óscar Lapuente-Santana, Gregor Sturm, Joan Kant, Markus Ausserhofer, Constantin Zackl, Maria Zopoglou, Nicholas McGranahan, Dietmar Rieder, Zlatko Trajanoski, Noel Filipe da Cunha Carvalho de Miranda, Federica Eduati, Francesca Finotello

    Diterbitkan 2024-08-01
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  7. 7
    Plk1 overexpression induces chromosomal instability and suppresses tumor development

    Plk1 overexpression induces chromosomal instability and suppresses tumor development oleh Guillermo de Cárcer, Sharavan Vishaan Venkateswaran, Lorena Salgueiro, Aicha El Bakkali, Kalman Somogyi, Konstantina Rowald, Pablo Montañés, Manuel Sanclemente, Beatriz Escobar, Alba de Martino, Nicholas McGranahan, Marcos Malumbres, Rocío Sotillo

    Diterbitkan 2018-08-01
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  8. 8
    Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.

    Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity. oleh Thomas B K Watkins, Emma C Colliver, Matthew R Huska, Tom L Kaufmann, Emilia L Lim, Cody B Duncan, Kerstin Haase, Peter Van Loo, Charles Swanton, Nicholas McGranahan, Roland F Schwarz

    Diterbitkan 2023-10-01
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  9. 9
    Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology

    Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology oleh Oliver J. Ziff, Jacob Neeves, Jamie Mitchell, Giulia Tyzack, Carlos Martinez-Ruiz, Raphaelle Luisier, Anob M. Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J. Boulton, Ammar Al-Chalabi, Gavin Kelly, Jack Humphrey, Rickie Patani

    Diterbitkan 2023-04-01
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  10. 10
    ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA

    ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA oleh Ariana Huebner, James R. M. Black, Francesca Sarno, Roberto Pazo, Ignacio Juez, Laura Medina, Rocio Garcia-Carbonero, Carmen Guillén, Jaime Feliú, Carolina Alonso, Carlota Arenillas, Ana Belén Moreno-Cárdenas, Helena Verdaguer, Teresa Macarulla, Manuel Hidalgo, Nicholas McGranahan, Rodrigo A. Toledo

    Diterbitkan 2023-04-01
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  11. 11
    Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma

    Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma oleh Nikolaj Pagh Kristensen, Christina Heeke, Siri A. Tvingsholm, Annie Borch, Arianna Draghi, Michael D. Crowther, Ibel Carri, Kamilla K. Munk, Jeppe Sejerø Holm, Anne-Mette Bjerregaard, Amalie Kai Bentzen, Andrea M. Marquard, Zoltan Szallasi, Nicholas McGranahan, Rikke Andersen, Morten Nielsen, Göran B. Jönsson, Marco Donia, Inge Marie Svane, Sine Reker Hadrup

    Diterbitkan 2022-01-01
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  12. 12
    Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

    Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling oleh Inma M. Berenjeno, Roberto Piñeiro, Sandra D. Castillo, Wayne Pearce, Nicholas McGranahan, Sally M. Dewhurst, Valerie Meniel, Nicolai J. Birkbak, Evelyn Lau, Laurent Sansregret, Daniele Morelli, Nnennaya Kanu, Shankar Srinivas, Mariona Graupera, Victoria E. R. Parker, Karen G. Montgomery, Larissa S. Moniz, Cheryl L. Scudamore, Wayne A. Phillips, Robert K. Semple, Alan Clarke, Charles Swanton, Bart Vanhaesebroeck

    Diterbitkan 2017-11-01
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  13. 13
    Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas

    Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas oleh Xin Hu, Marcos R. Estecio, Runzhe Chen, Alexandre Reuben, Linghua Wang, Junya Fujimoto, Jian Carrot-Zhang, Nicholas McGranahan, Lisha Ying, Junya Fukuoka, Chi-Wan Chow, Hoa H. N. Pham, Myrna C. B. Godoy, Brett W. Carter, Carmen Behrens, Jianhua Zhang, Mara B. Antonoff, Boris Sepesi, Yue Lu, Harvey I. Pass, Humam Kadara, Paul Scheet, Ara A. Vaporciyan, John V. Heymach, Ignacio I. Wistuba, J. Jack Lee, P. Andrew Futreal, Dan Su, Jean-Pierre J. Issa, Jianjun Zhang

    Diterbitkan 2021-01-01
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  14. 14
    Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer

    Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer oleh Filipe Correia Martins, Dominique-Laurent Couturier, Ines de Santiago, Carolin Margarethe Sauer, Maria Vias, Mihaela Angelova, Deborah Sanders, Anna Piskorz, James Hall, Karen Hosking, Anumithra Amirthanayagam, Sabina Cosulich, Larissa Carnevalli, Barry Davies, Thomas B. K. Watkins, Ionut G. Funingana, Helen Bolton, Krishnayan Haldar, John Latimer, Peter Baldwin, Robin Crawford, Matthew Eldridge, Bristi Basu, Mercedes Jimenez-Linan, Andrew W. Mcpherson, Nicholas McGranahan, Kevin Litchfield, Sohrab P. Shah, Iain McNeish, Carlos Caldas, Gerard Evan, Charles Swanton, James D. Brenton

    Diterbitkan 2022-10-01
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  15. 15
    Identifying key questions in the ecology and evolution of cancer

    Identifying key questions in the ecology and evolution of cancer oleh Antoine M. Dujon, Athena Aktipis, Catherine Alix‐Panabières, Sarah R. Amend, Amy M. Boddy, Joel S. Brown, Jean‐Pascal Capp, James DeGregori, Paul Ewald, Robert Gatenby, Marco Gerlinger, Mathieu Giraudeau, Rodrigo K. Hamede, Elsa Hansen, Irina Kareva, Carlo C. Maley, Andriy Marusyk, Nicholas McGranahan, Michael J. Metzger, Aurora M. Nedelcu, Robert Noble, Leonard Nunney, Kenneth J. Pienta, Kornelia Polyak, Pascal Pujol, Andrew F. Read, Benjamin Roche, Susanne Sebens, Eric Solary, Kateřina Staňková, Holly Swain Ewald, Frédéric Thomas, Beata Ujvari

    Diterbitkan 2021-04-01
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  16. 16
    MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

    MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically oleh Enkhtsetseg Munkhbaatar, Michelle Dietzen, Deepti Agrawal, Martina Anton, Moritz Jesinghaus, Melanie Boxberg, Nicole Pfarr, Pidassa Bidola, Sebastian Uhrig, Ulrike Höckendorf, Anna-Lena Meinhardt, Adam Wahida, Irina Heid, Rickmer Braren, Ritu Mishra, Arne Warth, Thomas Muley, Patrina S. P. Poh, Xin Wang, Stefan Fröhling, Katja Steiger, Julia Slotta-Huspenina, Martijn van Griensven, Franz Pfeiffer, Sebastian Lange, Roland Rad, Magda Spella, Georgios T. Stathopoulos, Jürgen Ruland, Florian Bassermann, Wilko Weichert, Andreas Strasser, Caterina Branca, Mathias Heikenwalder, Charles Swanton, Nicholas McGranahan, Philipp J. Jost

    Diterbitkan 2020-09-01
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  17. 17
    Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features

    Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features oleh Hitoshi Dejima, Xin Hu, Runzhe Chen, Jiexin Zhang, Junya Fujimoto, Edwin R. Parra, Cara Haymaker, Shawna M. Hubert, Dzifa Duose, Luisa M. Solis, Dan Su, Junya Fukuoka, Kazuhiro Tabata, Hoa H. N. Pham, Nicholas Mcgranahan, Baili Zhang, Jie Ye, Lisha Ying, Latasha Little, Curtis Gumbs, Chi-Wan Chow, Marcos Roberto Estecio, Myrna C. B. Godoy, Mara B. Antonoff, Boris Sepesi, Harvey I. Pass, Carmen Behrens, Jianhua Zhang, Ara A. Vaporciyan, John V. Heymach, Paul Scheet, J. Jack Lee, Jia Wu, P. Andrew Futreal, Alexandre Reuben, Humam Kadara, Ignacio I. Wistuba, Jianjun Zhang

    Diterbitkan 2021-05-01
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  18. 18
    Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models

    Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models oleh Robert E. Hynds, Ariana Huebner, David R. Pearce, Mark S. Hill, Ayse U. Akarca, David A. Moore, Sophia Ward, Kate H. C. Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A. Wilson, Oriol Pich, Carlos Martínez-Ruiz, A. S. Md Mukarram Hossain, Simon P. Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak Chandrasekharan, Krishna K. Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E. Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J. Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A. J. Crosbie, Caroline Dive, Sergio A. Quezada, Sam M. Janes, Mariam Jamal-Hanjani, Teresa Marafioti, TRACERx consortium, Nicholas McGranahan, Charles Swanton

    Diterbitkan 2024-05-01
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  19. 19
    Author Correction: Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

    Author Correction: Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma oleh Xin Hu, Junya Fujimoto, Lisha Ying, Junya Fukuoka, Kazuto Ashizawa, Wenyong Sun, Alexandre Reuben, Chi-Wan Chow, Nicholas McGranahan, Runzhe Chen, Jinlin Hu, Myrna C. Godoy, Kazuhiro Tabata, Kishio Kuroda, Lei Shi, Jun Li, Carmen Behrens, Edwin Roger Parra, Latasha D. Little, Curtis Gumbs, Xizeng Mao, Xingzhi Song, Samantha Tippen, Rebecca L. Thornton, Humam Kadara, Paul Scheet, Emily Roarty, Edwin Justin Ostrin, Xu Wang, Brett W. Carter, Mara B. Antonoff, Jianhua Zhang, Ara A. Vaporciyan, Harvey Pass, Stephen G. Swisher, John V. Heymach, J. Jack Lee, Ignacio I. Wistuba, Waun Ki Hong, P. Andrew Futreal, Dan Su, Jianjun Zhang

    Diterbitkan 2021-05-01
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  20. 20
    Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

    Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma oleh Xin Hu, Junya Fujimoto, Lisha Ying, Junya Fukuoka, Kazuto Ashizawa, Wenyong Sun, Alexandre Reuben, Chi-Wan Chow, Nicholas McGranahan, Runzhe Chen, Jinlin Hu, Myrna C. Godoy, Kazuhiro Tabata, Kishio Kuroda, Lei Shi, Jun Li, Carmen Behrens, Edwin Roger Parra, Latasha D. Little, Curtis Gumbs, Xizeng Mao, Xingzhi Song, Samantha Tippen, Rebecca L. Thornton, Humam Kadara, Paul Scheet, Emily Roarty, Edwin Justin Ostrin, Xu Wang, Brett W. Carter, Mara B. Antonoff, Jianhua Zhang, Ara A. Vaporciyan, Harvey Pass, Stephen G. Swisher, John V. Heymach, J. Jack Lee, Ignacio I. Wistuba, Waun Ki Hong, P. Andrew Futreal, Dan Su, Jianjun Zhang

    Diterbitkan 2019-07-01
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