Hasil Pencarian - Michael Alonso

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  1. 1
    Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases

    Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases oleh Francesco Vallania, Andrew Tam, Shane Lofgren, Steven Schaffert, Tej D. Azad, Erika Bongen, Winston Haynes, Meia Alsup, Michael Alonso, Mark Davis, Edgar Engleman, Purvesh Khatri

    Diterbitkan 2018-11-01
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  2. 2
    605 Systemically administered HER2-targeted ISACs provoke a rapid, local response that engages the innate and adaptive arms of the immune system to eradicate tumors in preclinical models

    605 Systemically administered HER2-targeted ISACs provoke a rapid, local response that engages the innate and adaptive arms of the immune system to eradicate tumors in preclinical... oleh Marcin Kowanetz, Po Ho, Shelley Ackerman, Heidi LeBlanc, David Dornan, Michael Alonso, Cecelia Pearson, Andrew Luo, Richard Laura, Justin Kenkel, LIsa Blum, Angela Luo, Matthew Zhou, Joshua Gregorio, Brian Safina

    Diterbitkan 2020-11-01
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  3. 3
    603 Covalent attachment of a TLR7/8 agonist to tumor-targeting antibodies drives potent anti-tumor efficacy by synergistically activating FcgR- and TLR- signaling and enables safe systemic administration

    603 Covalent attachment of a TLR7/8 agonist to tumor-targeting antibodies drives potent anti-tumor efficacy by synergistically activating FcgR- and TLR- signaling and enables safe... oleh David Jackson, Shelley Ackerman, David Dornan, Michael Alonso, Felix Hartmann, Cecelia Pearson, Joseph Gonzalez, Po Yi Ho, Samuel Kimmey, Andrew Luo, Benjamin Ackerman, Arthur Lee, Richard Laura, Jason Paik, Karla Henning, Steven Chapin, Bruce Devens, Sean Bendall, Edgar Engleman

    Diterbitkan 2020-11-01
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  4. 4
    401 Phase 1/2 study of novel HER2-targeting, TLR7/8 immune-stimulating antibody conjugate (ISAC) BDC-1001 with or without immune checkpoint inhibitor in patients with advanced HER2-expressing solid tumors

    401 Phase 1/2 study of novel HER2-targeting, TLR7/8 immune-stimulating antibody conjugate (ISAC) BDC-1001 with or without immune checkpoint inhibitor in patients with advanced HER2... oleh Marcin Kowanetz, Manish Sharma, Jeeyun Lee, Leisha Emens, Keun-Wook Lee, Yoon-Koo Kang, Paula Pohlmann, Glenn Hanna, Ecaterina Ileana Dumbrava, Daniel Catenacci, Dejan Juric, Bob Li, Kathleen Moore, Mark Pegram, Antoinette Tan, Shelley Ackerman, Heidi LeBlanc, David Dornan, Michael Alonso, Edith Perez

    Diterbitkan 2020-11-01
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  5. 5
    784 BDC-2034: discovery of a CEA-targeting immune-stimulating antibody conjugate (ISAC) for solid tumors

    784 BDC-2034: discovery of a CEA-targeting immune-stimulating antibody conjugate (ISAC) for solid tumors oleh Marcin Kowanetz, Shelley Ackerman, David Dornan, Michael Alonso, Edith Perez, Cecelia Pearson, Arthur Lee, Karla Henning, Steven Chapin, LIsa Blum, Angela Luo, Matthew Zhou, Brian Safina, Amreen Husain, William Mallet, Rishali Gadkari, Laughing Bear Torrez Dulgeroff, AAngela Luondrew Luo, Jennifer Melrose, Jess Nolin, Puneet Anand, Ganapathy Sarma, Liz Bogaert, Romas Kudirka, Yuyi Shen

    Diterbitkan 2021-11-01
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