Hasil Pencarian - Michael J. Eck

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  1. 1
    Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation.

    Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation. oleh Daniel Lietha, Michael J Eck

    Diterbitkan 2008-01-01
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  2. 2
    Crystal Structure of the FERM-SH2 Module of Human Jak2.

    Crystal Structure of the FERM-SH2 Module of Human Jak2. oleh Randall McNally, Angela V Toms, Michael J Eck

    Diterbitkan 2016-01-01
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  3. 3
    Crystal structure of a complex between amino and carboxy terminal fragments of mDia1: insights into autoinhibition of diaphanous-related formins.

    Crystal structure of a complex between amino and carboxy terminal fragments of mDia1: insights into autoinhibition of diaphanous-related formins. oleh Azin Nezami, Florence Poy, Angela Toms, Wei Zheng, Michael J Eck

    Diterbitkan 2010-09-01
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  4. 4
    Cryo-EM structure of a RAS/RAF recruitment complex

    Cryo-EM structure of a RAS/RAF recruitment complex oleh Eunyoung Park, Shaun Rawson, Anna Schmoker, Byeong-Won Kim, Sehee Oh, Kangkang Song, Hyesung Jeon, Michael J. Eck

    Diterbitkan 2023-07-01
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  5. 5
    PH domain-mediated autoinhibition and oncogenic activation of Akt

    PH domain-mediated autoinhibition and oncogenic activation of Akt oleh Hwan Bae, Thibault Viennet, Eunyoung Park, Nam Chu, Antonieta Salguero, Michael J Eck, Haribabu Arthanari, Philip A Cole

    Diterbitkan 2022-08-01
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  6. 6
    Publisher Correction: Cryo-EM structure of a RAS/RAF recruitment complex

    Publisher Correction: Cryo-EM structure of a RAS/RAF recruitment complex oleh Eunyoung Park, Shaun Rawson, Anna Schmoker, Byeong-Won Kim, Sehee Oh, Kangkang Song, Hyesung Jeon, Michael J. Eck

    Diterbitkan 2023-09-01
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  7. 7
    CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells

    CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells oleh Jing Zhang, Xueliang Gao, Fabienne Schmit, Guillaume Adelmant, Michael J. Eck, Jarrod A. Marto, Jean J. Zhao, Thomas M. Roberts

    Diterbitkan 2017-07-01
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  8. 8
    Crystal structure of a coiled-coil domain from human ROCK I.

    Crystal structure of a coiled-coil domain from human ROCK I. oleh Daqi Tu, Yiqun Li, Hyun Kyu Song, Angela V Toms, Christopher J Gould, Scott B Ficarro, Jarrod A Marto, Bruce L Goode, Michael J Eck

    Diterbitkan 2011-03-01
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  9. 9
    Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer

    Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer oleh Ikuko Takeda Nakamura, Shinji Kohsaka, Masachika Ikegami, Hiroshi Ikeuchi, Toshihide Ueno, Kunhua Li, Tyler S. Beyett, Takafumi Koyama, Toshio Shimizu, Noboru Yamamoto, Fumiyuki Takahashi, Kazuhisa Takahashi, Michael J. Eck, Hiroyuki Mano

    Diterbitkan 2021-07-01
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  10. 10
    Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality

    Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality oleh Zhengnian Li, Jie Jiang, Scott B. Ficarro, Tyler S. Beyett, Ciric To, Isidoro Tavares, Yingde Zhu, Jiaqi Li, Michael J. Eck, Pasi A. Jänne, Jarrod A. Marto, Tinghu Zhang, Jianwei Che, Nathanael S. Gray

    Diterbitkan 2024-02-01
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  11. 11
    Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors

    Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors oleh Tyler S. Beyett, Ciric To, David E. Heppner, Jaimin K. Rana, Anna M. Schmoker, Jaebong Jang, Dries J. H. De Clercq, Gabriel Gomez, David A. Scott, Nathanael S. Gray, Pasi A. Jänne, Michael J. Eck

    Diterbitkan 2022-05-01
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  12. 12
    Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression

    Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression oleh Weikang Cai, Masaji Sakaguchi, Andre Kleinridders, Gonzalo Gonzalez-Del Pino, Jonathan M. Dreyfuss, Brian T. O’Neill, Alfred K. Ramirez, Hui Pan, Jonathon N. Winnay, Jeremie Boucher, Michael J. Eck, C. Ronald Kahn

    Diterbitkan 2017-03-01
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  13. 13
    MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

    MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells oleh Yubao Wang, Young-Mi Lee, Lukas Baitsch, Alan Huang, Yi Xiang, Haoxuan Tong, Ana Lako, Thanh Von, Christine Choi, Elgene Lim, Junxia Min, Li Li, Frank Stegmeier, Robert Schlegel, Michael J Eck, Nathanael S Gray, Timothy J Mitchison, Jean J Zhao

    Diterbitkan 2014-05-01
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  14. 14
    Correction: MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

    Correction: MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells oleh Yubao Wang, Young-Mi Li, Lukas Baitsch, Alan Huang, Yi Xiang, Haoxuan Tong, Ana Lako, Thanh Von, Christine Choi, Elgene Lim, Junxia Min, Li Li, Frank Stegmeier, Robert Schlegel, Michael J Eck, Nathanael S Gray, Timothy J Mitchison, Jean J Zhao

    Diterbitkan 2018-03-01
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  15. 15
    Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1

    Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1 oleh Daqi Tu, Zehua Zhu, Alicia Y. Zhou, Cai-hong Yun, Kyung-Eun Lee, Angela V. Toms, Yiqun Li, Gavin P. Dunn, Edmond Chan, Tran Thai, Shenghong Yang, Scott B. Ficarro, Jarrod A. Marto, Hyesung Jeon, William C. Hahn, David A. Barbie, Michael J. Eck

    Diterbitkan 2013-03-01
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  16. 16
    MELK is not necessary for the proliferation of basal-like breast cancer cells

    MELK is not necessary for the proliferation of basal-like breast cancer cells oleh Hai-Tsang Huang, Hyuk-Soo Seo, Tinghu Zhang, Yubao Wang, Baishan Jiang, Qing Li, Dennis L Buckley, Behnam Nabet, Justin M Roberts, Joshiawa Paulk, Shiva Dastjerdi, Georg E Winter, Hilary McLauchlan, Jennifer Moran, James E Bradner, Michael J Eck, Sirano Dhe-Paganon, Jean J Zhao, Nathanael S Gray

    Diterbitkan 2017-09-01
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  17. 17
    Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors

    Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors oleh Florian Wittlinger, Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner, Brandon T. Oligny, Surbhi P. Chitnis, Tyler S. Beyett, Alexander Rasch, Brian Buckley, Daniel A. Urul, Tatiana Shaurova, Earl W. May, Erik M. Schaefer, Michael J. Eck, Pamela A. Hershberger, Antti Poso, Stefan A. Laufer, David E. Heppner

    Diterbitkan 2024-02-01
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  18. 18
    Data publication with the structural biology data grid supports live analysis

    Data publication with the structural biology data grid supports live analysis oleh Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James S. Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz

    Diterbitkan 2016-03-01
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