IL-18–secreting CAR T cells targeting DLL3 are highly effective in small cell lung cancer models by Janneke E. Jaspers, Jonathan F. Khan, William D. Godfrey, Andrea V. Lopez, Metamia Ciampricotti, Charles M. Rudin, Renier J. Brentjens

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MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer by Rebecca Caeser, Christopher Hulton, Emily Costa, Vidushi Durani, Megan Little, Xiaoping Chen, Sam E. Tischfield, Marina Asher, Faruk Erdem Kombak, Shweta S. Chavan, Nisargbhai S. Shah, Metamia Ciampricotti, Elisa de Stanchina, John T. Poirier, Charles M. Rudin, Triparna Sen

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Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages by Kelly Kersten, Seth B. Coffelt, Marlous Hoogstraat, Niels J.M. Verstegen, Kim Vrijland, Metamia Ciampricotti, Chris W. Doornebal, Cheei-Sing Hau, Max D. Wellenstein, Camilla Salvagno, Parul Doshi, Esther H. Lips, Lodewyk F.A. Wessels, Karin E. de Visser

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KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance by Anastasia-Maria Zavitsanou, Ray Pillai, Yuan Hao, Warren L. Wu, Eric Bartnicki, Triantafyllia Karakousi, Sahith Rajalingam, Alberto Herrera, Angeliki Karatza, Ali Rashidfarrokhi, Sabrina Solis, Metamia Ciampricotti, Anna H. Yeaton, Ellie Ivanova, Corrin A. Wohlhieter, Terkild B. Buus, Makiko Hayashi, Burcu Karadal-Ferrena, Harvey I. Pass, John T. Poirier, Charles M. Rudin, Kwok-Kin Wong, Andre L. Moreira, Kamal M. Khanna, Aristotelis Tsirigos, Thales Papagiannakopoulos, Sergei B. Koralov

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Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation by Alvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian A. Zhan, Maysun M. Hasan, Shweta S. Chavan, Fanli Meng, Fathema Uddin, Viola Allaj, Parvathy Manoj, Nisargbhai S. Shah, Joseph M. Chan, Metamia Ciampricotti, Andrew Chow, Michael Offin, Jordana Ray-Kirton, Jacklynn D. Egger, Umesh K. Bhanot, Irina Linkov, Marina Asher, Michael H. Roehrl, Katia Ventura, Juan Qiu, Elisa de Stanchina, Jason C. Chang, Natasha Rekhtman, Brian Houck-Loomis, Richard P. Koche, Helena A. Yu, Triparna Sen, Charles M. Rudin

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CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation by Alvaro Quintanal-Villalonga, Kenta Kawasaki, Esther Redin, Fathema Uddin, Swanand Rakhade, Vidushi Durani, Amin Sabet, Moniquetta Shafer, Wouter R. Karthaus, Samir Zaidi, Yingqian A. Zhan, Parvathy Manoj, Harsha Sridhar, Dennis Kinyua, Hong Zhong, Barbara P. Mello, Metamia Ciampricotti, Umesh K. Bhanot, Irina Linkov, Juan Qiu, Radhika A. Patel, Colm Morrissey, Sanjoy Mehta, Jesse Barnes, Michael C. Haffner, Nicholas D. Socci, Richard P. Koche, Elisa de Stanchina, Sonia Molina-Pinelo, Sohrab Salehi, Helena A. Yu, Joseph M. Chan, Charles M. Rudin

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