Search Results - Margarida D Amaral

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  1. 1
    What Can RNA-Based Therapy Do for Monogenic Diseases?

    What Can RNA-Based Therapy Do for Monogenic Diseases? by Luka A. Clarke, Margarida D. Amaral

    Published 2023-01-01
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  2. 2
    Cross-talk of inflammatory mediators and airway epithelium reveals the cystic fibrosis transmembrane conductance regulator as a major target

    Cross-talk of inflammatory mediators and airway epithelium reveals the cystic fibrosis transmembrane conductance regulator as a major target by Filipa B. Simões, Arthur Kmit, Margarida D. Amaral

    Published 2021-12-01
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  3. 3
    What Role Does CFTR Play in Development, Differentiation, Regeneration and Cancer?

    What Role Does CFTR Play in Development, Differentiation, Regeneration and Cancer? by Margarida D. Amaral, Margarida C. Quaresma, Ines Pankonien

    Published 2020-04-01
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  4. 4
    Neuronal reprograming of protein homeostasis by calcium-dependent regulation of the heat shock response.

    Neuronal reprograming of protein homeostasis by calcium-dependent regulation of the heat shock response. by M Catarina Silva, Margarida D Amaral, Richard I Morimoto

    Published 2013-08-01
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  5. 5
    CFTR, Cell Junctions and the Cytoskeleton

    CFTR, Cell Junctions and the Cytoskeleton by Ines Pankonien, Margarida C. Quaresma, Cláudia S. Rodrigues, Margarida D. Amaral

    Published 2022-02-01
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  6. 6
    Impact of KLF4 on Cell Proliferation and Epithelial Differentiation in the Context of Cystic Fibrosis

    Impact of KLF4 on Cell Proliferation and Epithelial Differentiation in the Context of Cystic Fibrosis by Luís Sousa, Ines Pankonien, Filipa B. Simões, Marc Chanson, Margarida D. Amaral

    Published 2020-09-01
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  7. 7
    Rare Trafficking CFTR Mutations Involve Distinct Cellular Retention Machineries and Require Different Rescuing Strategies

    Rare Trafficking CFTR Mutations Involve Distinct Cellular Retention Machineries and Require Different Rescuing Strategies by Sofia S. Ramalho, Iris A. L. Silva, Margarida D. Amaral, Carlos M. Farinha

    Published 2021-12-01
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  8. 8
    KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway

    KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway by Luis Sousa, Ines Pankonien, Luka A Clarke, Iris Silva, Karl Kunzelmann, Margarida D Amaral

    Published 2020-07-01
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  9. 9
    A genetic screening strategy identifies novel regulators of the proteostasis network.

    A genetic screening strategy identifies novel regulators of the proteostasis network. by M Catarina Silva, Susan Fox, Monica Beam, Happy Thakkar, Margarida D Amaral, Richard I Morimoto

    Published 2011-12-01
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  10. 10
    Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids

    Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids by João F. Ferreira, Iris A. L. Silva, Hugo M. Botelho, Margarida D. Amaral, Carlos M. Farinha

    Published 2022-07-01
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  11. 11
    Synergy in Cystic Fibrosis Therapies: Targeting SLC26A9

    Synergy in Cystic Fibrosis Therapies: Targeting SLC26A9 by Madalena C. Pinto, Margarida C. Quaresma, Iris A. L. Silva, Violeta Railean, Sofia S. Ramalho, Margarida D. Amaral

    Published 2021-12-01
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  12. 12
    Pediatric population with cystic fibrosis in the centre of Portugal: candidates for new therapies

    Pediatric population with cystic fibrosis in the centre of Portugal: candidates for new therapies by Juliana Roda, Teresa Teixeira, Iris AI Silva, Teresa Reis Silva, Ricardo Ferreira, Margarida D. Amaral, Guiomar Oliveira

    Published 2022-03-01
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  13. 13
    Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells

    Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells by Lúcia Santos, Rui Nascimento, Aires Duarte, Violeta Railean, Margarida D. Amaral, Patrick T. Harrison, Margarida Gama-Carvalho, Carlos M. Farinha

    Published 2023-02-01
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  14. 14
    The K+ channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients.

    The K+ channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients. by Eva K Roth, Stephanie Hirtz, Julia Duerr, Daniel Wenning, Irmgard Eichler, Hans H Seydewitz, Margarida D Amaral, Marcus A Mall

    Published 2011-01-01
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  15. 15
    Personalized medicine: Function of CFTR variant p.Arg334Trp is rescued by currently available CFTR modulators

    Personalized medicine: Function of CFTR variant p.Arg334Trp is rescued by currently available CFTR modulators by Violeta Railean, Cláudia S. Rodrigues, Sofia S. Ramalho, Iris A. L. Silva, Jan Bartosch, Carlos M. Farinha, Ines Pankonien, Margarida D. Amaral

    Published 2023-03-01
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  16. 16
    CyFi-MAP: an interactive pathway-based resource for cystic fibrosis

    CyFi-MAP: an interactive pathway-based resource for cystic fibrosis by Catarina Pereira, Alexander Mazein, Carlos M. Farinha, Michael A. Gray, Karl Kunzelmann, Marek Ostaszewski, Irina Balaur, Margarida D. Amaral, Andre O. Falcao

    Published 2021-11-01
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  17. 17
    Full Rescue of F508del-CFTR Processing and Function by CFTR Modulators Can Be Achieved by Removal of Two Regulatory Regions

    Full Rescue of F508del-CFTR Processing and Function by CFTR Modulators Can Be Achieved by Removal of Two Regulatory Regions by Inna Uliyakina, Hugo M. Botelho, Ana C. da Paula, Sara Afonso, Miguel J. Lobo, Verónica Felício, Carlos M. Farinha, Margarida D. Amaral

    Published 2020-06-01
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  18. 18
    Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis

    Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis by Nikhil T. Awatade, Inna Uliyakina, Carlos M. Farinha, Luka A. Clarke, Karina Mendes, Amparo Solé, Juan Pastor, Maria Margarida Ramos, Margarida D. Amaral

    Published 2015-02-01
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  19. 19
    Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum

    Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum by João D. Santos, Sara Canato, Ana S. Carvalho, Hugo M. Botelho, Kerman Aloria, Margarida D. Amaral, Rune Matthiesen, Andre O. Falcao, Carlos M. Farinha

    Published 2019-04-01
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  20. 20
    Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A

    Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A by Miquéias Lopes-Pacheco, Mafalda Bacalhau, Sofia S. Ramalho, Iris A. L. Silva, Filipa C. Ferreira, Graeme W. Carlile, David Y. Thomas, Carlos M. Farinha, John W. Hanrahan, Margarida D. Amaral

    Published 2022-01-01
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