Search Results - Luke W Thomas

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  1. 1
    The Contextual Essentiality of Mitochondrial Genes in Cancer

    The Contextual Essentiality of Mitochondrial Genes in Cancer by Luke W. Thomas, Margaret Ashcroft

    Published 2021-10-01
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  2. 2
    Corrigendum: CHCHD4 Regulates Intracellular Oxygenation and Perinuclear Distribution of Mitochondria

    Corrigendum: CHCHD4 Regulates Intracellular Oxygenation and Perinuclear Distribution of Mitochondria by Luke W. Thomas, Oliver Staples, Mark Turmaine, Margaret Ashcroft

    Published 2019-01-01
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  3. 3
    CHCHD4 Regulates Intracellular Oxygenation and Perinuclear Distribution of Mitochondria

    CHCHD4 Regulates Intracellular Oxygenation and Perinuclear Distribution of Mitochondria by Luke W. Thomas, Oliver Staples, Mark Turmaine, Margaret Ashcroft

    Published 2017-04-01
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  4. 4
    CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism

    CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism by Luke W. Thomas, Cinzia Esposito, Jenna M. Stephen, Ana S. H. Costa, Christian Frezza, Thomas S. Blacker, Gyorgy Szabadkai, Margaret Ashcroft

    Published 2019-07-01
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  5. 5
    CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain

    CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain by Luke W. Thomas, Jenna M. Stephen, Cinzia Esposito, Simon Hoer, Robin Antrobus, Afshan Ahmed, Hasan Al-Habib, Margaret Ashcroft

    Published 2019-03-01
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  6. 6
    Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1.

    Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1. by Luke W Thomas, Connie Lam, Richard E Clark, Michael R H White, David G Spiller, Robert J Moots, Steven W Edwards

    Published 2012-01-01
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  7. 7
    Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia

    Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia by Luke W. Thomas, Cinzia Esposito, Rachel E. Morgan, Stacey Price, Jamie Young, Steven P. Williams, Lucas A. Maddalena, Ultan McDermott, Margaret Ashcroft

    Published 2021-05-01
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  8. 8
    The mitochondrial oxidoreductase CHCHD4 is present in a semi-oxidized state in vivo

    The mitochondrial oxidoreductase CHCHD4 is present in a semi-oxidized state in vivo by Alican J. Erdogan, Muna Ali, Markus Habich, Silja L. Salscheider, Laura Schu, Carmelina Petrungaro, Luke W. Thomas, Margaret Ashcroft, Lars I. Leichert, Leticia Prates Roma, Jan Riemer

    Published 2018-07-01
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  9. 9
    Corrigendum: VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function

    Corrigendum: VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function by Thomas Briston, Jenna M. Stephen, Luke W. Thomas, Cinzia Esposito, Yuen-Li Chung, Saiful E. Syafruddin, Mark Turmaine, Lucas A. Maddalena, Basma Greef, Gyorgy Szabadkai, Gyorgy Szabadkai, Gyorgy Szabadkai, Patrick H. Maxwell, Sakari Vanharanta, Margaret Ashcroft

    Published 2021-09-01
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  10. 10
    VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function

    VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function by Thomas Briston, Jenna M. Stephen, Luke W. Thomas, Cinzia Esposito, Yuen-Li Chung, Saiful E. Syafruddin, Mark Turmaine, Lucas A. Maddalena, Basma Greef, Gyorgy Szabadkai, Gyorgy Szabadkai, Gyorgy Szabadkai, Patrick H. Maxwell, Sakari Vanharanta, Margaret Ashcroft

    Published 2018-10-01
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  11. 11
    Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress

    Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress by Katie A. O’Brien, Ben D. McNally, Alice P. Sowton, Antonio Murgia, James Armitage, Luke W. Thomas, Fynn N. Krause, Lucas A. Maddalena, Ian Francis, Stefan Kavanagh, Dominic P. Williams, Margaret Ashcroft, Julian L. Griffin, Jonathan J. Lyon, Andrew J. Murray

    Published 2021-12-01
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