Hasil Pencarian - Lisa M. Ellerby

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  1. 1
    Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease

    Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease oleh Swati Naphade, Alexander Embusch, Kuruwitage Lakshika Madushani, Karen L. Ring, Karen L. Ring, Lisa M. Ellerby

    Diterbitkan 2018-02-01
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  2. 2
    TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration

    TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astroglios... oleh Jordi Creus-Muncunill, Jean Vianney Haure-Mirande, Daniele Mattei, Joanna Bons, Angie V. Ramirez, B. Wade Hamilton, Chuhyon Corwin, Sarah Chowdhury, Birgit Schilling, Lisa M. Ellerby, Michelle E. Ehrlich

    Diterbitkan 2024-03-01
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  3. 3
    Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells

    Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells oleh Karen L. Ring, Mahru C. An, Ningzhe Zhang, Robert N. O’Brien, Eliana Marisa Ramos, Fuying Gao, Robert Atwood, Barbara J. Bailus, Simon Melov, Sean D. Mooney, Giovanni Coppola, Lisa M. Ellerby

    Diterbitkan 2015-12-01
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  4. 4
    Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing

    Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing oleh Kizito-Tshitoko Tshilenge, Joanna Bons, Carlos Galicia Aguirre, Cristian Geronimo-Olvera, Samah Shah, Jacob Rose, Akos A. Gerencser, Sally K. Mak, Michelle E. Ehrlich, D. Cristopher Bragg, Birgit Schilling, Lisa M. Ellerby

    Diterbitkan 2024-01-01
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  5. 5
    Postnatal Conditional Deletion of <i>Bcl11b</i> in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington’s Disease

    Postnatal Conditional Deletion of <i>Bcl11b</i> in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington’s Disease oleh Sicheng Song, Jordi Creus Muncunill, Carlos Galicia Aguirre, Kizito-Tshitoko Tshilenge, B. Wade Hamilton, Akos A. Gerencser, Houda Benlhabib, Maria-Daniela Cirnaru, Mark Leid, Sean D. Mooney, Lisa M. Ellerby, Michelle E. Ehrlich

    Diterbitkan 2022-09-01
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  6. 6
    Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin

    Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin oleh Yuji Tanaka, Shuichi Igarashi, Masayuki Nakamura, Juliette Gafni, Cameron Torcassi, Gabrielle Schilling, Danielle Crippen, Jonathan D. Wood, Akira Sawa, Nancy A. Jenkins, Neal G. Copeland, David R. Borchelt, Christopher A. Ross, Lisa M. Ellerby

    Diterbitkan 2006-02-01
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  7. 7
    Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription

    Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription oleh Rui Gao, Anirban Chakraborty, Charlene Geater, Subrata Pradhan, Kara L Gordon, Jeffrey Snowden, Subo Yuan, Audrey S Dickey, Sanjeev Choudhary, Tetsuo Ashizawa, Lisa M Ellerby, Albert R La Spada, Leslie M Thompson, Tapas K Hazra, Partha S Sarkar

    Diterbitkan 2019-04-01
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  8. 8
    A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.

    A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease. oleh John P Miller, Bridget E Yates, Ismael Al-Ramahi, Ari E Berman, Mario Sanhueza, Eugene Kim, Maria de Haro, Francesco DeGiacomo, Cameron Torcassi, Jennifer Holcomb, Juliette Gafni, Sean D Mooney, Juan Botas, Lisa M Ellerby, Robert E Hughes

    Diterbitkan 2012-01-01
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  9. 9
    Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation

    Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation oleh Maria-Daniela Cirnaru, Sicheng Song, Kizito-Tshitoko Tshilenge, Chuhyon Corwin, Justyna Mleczko, Carlos Galicia Aguirre, Houda Benlhabib, Jaroslav Bendl, Pasha Apontes, John Fullard, Jordi Creus-Muncunill, Azadeh Reyahi, Ali M Nik, Peter Carlsson, Panos Roussos, Sean D Mooney, Lisa M Ellerby, Michelle E Ehrlich

    Diterbitkan 2021-10-01
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  10. 10
    Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

    Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity oleh Matan Sorek, Walaa Oweis, Malka Nissim-Rafinia, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean K. Simmons, Neville E. Sanjana, Xi Shi, Congyi Lu, Jen Q. Pan, Xiaohong Xu, Mahmoud A. Pouladi, Lisa M. Ellerby, Feng Zhang, Joshua Z. Levin, Eran Meshorer

    Diterbitkan 2021-03-01
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  11. 11
    Huntingtin interacting proteins are genetic modifiers of neurodegeneration.

    Huntingtin interacting proteins are genetic modifiers of neurodegeneration. oleh Linda S Kaltenbach, Eliana Romero, Robert R Becklin, Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt, Guang-Ho Cha, Lubna Ukani, Cindy Lou Chepanoske, Yuejun Zhen, Sudhir Sahasrabudhe, James Olson, Cornelia Kurschner, Lisa M Ellerby, John M Peltier, Juan Botas, Robert E Hughes

    Diterbitkan 2007-05-01
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  12. 12
    OXR1 maintains the retromer to delay brain aging under dietary restriction

    OXR1 maintains the retromer to delay brain aging under dietary restriction oleh Kenneth A. Wilson, Sudipta Bar, Eric B. Dammer, Enrique M. Carrera, Brian A. Hodge, Tyler A. U. Hilsabeck, Joanna Bons, George W. Brownridge, Jennifer N. Beck, Jacob Rose, Melia Granath-Panelo, Christopher S. Nelson, Grace Qi, Akos A. Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B. Brem, Philippe M. Campeau, Hugo J. Bellen, Birgit Schilling, Nicholas T. Seyfried, Lisa M. Ellerby, Pankaj Kapahi

    Diterbitkan 2024-01-01
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