Hasil Pencarian - Linda S Wicker

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  1. 1
    Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus [version 2; peer review: 2 approved, 1 approved with reservations]

    Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus [version 2; peer review: 2 approved, 1 app... oleh Dominik Trzupek, Fiona Hamey, Mercede Lee, John A. Todd, Linda S. Wicker, Ricardo C. Ferreira

    Diterbitkan 2022-05-01
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  2. 2
    Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus [version 1; peer review: 1 approved, 2 approved with reservations]

    Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus [version 1; peer review: 1 approved, 2 app... oleh Dominik Trzupek, Fiona Hamey, Mercede Lee, John A. Todd, Linda S. Wicker, Ricardo C. Ferreira

    Diterbitkan 2021-06-01
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  3. 3
    Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases

    Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases oleh Jennifer L. Asimit, Daniel B. Rainbow, Mary D. Fortune, Nastasiya F. Grinberg, Linda S. Wicker, Chris Wallace

    Diterbitkan 2019-07-01
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  4. 4
    SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile

    SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile oleh Jia-Yuan Zhang, Justin P. Whalley, Julian C. Knight, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira

    Diterbitkan 2023-09-01
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  5. 5
    In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment

    In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment oleh Ricardo C. Ferreira, Daniel B. Rainbow, Arcadio Rubio García, Marcin L. Pekalski, Linsey Porter, João J. Oliveira, Frank Waldron-Lynch, Linda S. Wicker, John A. Todd

    Diterbitkan 2017-06-01
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  6. 6
    Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes.

    Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes. oleh Nora M Kochupurakkal, Annie J Kruger, Sudipta Tripathi, Bing Zhu, La Tonya Adams, Daniel B Rainbow, Aldo Rossini, Dale L Greiner, Mohamed H Sayegh, Linda S Wicker, Indira Guleria

    Diterbitkan 2014-01-01
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  7. 7
    Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice.

    Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice. oleh Jochen Mattner, Javid P Mohammed, Michael E Fusakio, Claudia Giessler, Carl-Philipp Hackstein, Robert Opoka, Marius Wrage, Regina Schey, Jan Clark, Heather I Fraser, Daniel B Rainbow, Linda S Wicker

    Diterbitkan 2019-06-01
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  8. 8
    Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

    Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis oleh Dominik Trzupek, Melanie Dunstan, Antony J. Cutler, Mercede Lee, Leila Godfrey, Lorna Jarvis, Daniel B. Rainbow, Dominik Aschenbrenner, Joanne L. Jones, Holm H. Uhlig, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira

    Diterbitkan 2020-06-01
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  9. 9
    The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus

    The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus oleh João J. Oliveira, Sarah Karrar, Daniel B. Rainbow, Christopher L. Pinder, Pamela Clarke, Arcadio Rubio García, Osama Al-Assar, Keith Burling, Sian Morris, Richard Stratton, Tim J. Vyse, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira

    Diterbitkan 2018-07-01
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  10. 10
    Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes

    Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes oleh Jia-Yuan Zhang, Fiona Hamey, Dominik Trzupek, Marius Mickunas, Mercede Lee, Leila Godfrey, Jennie H. M. Yang, Marcin L. Pekalski, Jane Kennet, Frank Waldron-Lynch, Mark L. Evans, Timothy I. M. Tree, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira

    Diterbitkan 2022-11-01
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  11. 11
    Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial [version 3; referees: 2 approved]

    Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial [version 3; referees: 2 approved] oleh Antony J. Cutler, Joao Oliveira, Ricardo C. Ferreira, Ben Challis, Neil M. Walker, Sarah Caddy, Jia Lu, Helen E. Stevens, Deborah J. Smyth, Marcin L. Pekalski, Jane Kennet, Kara M.D. Hunter, Ian Goodfellow, Linda S. Wicker, John A. Todd, Frank Waldron-Lynch

    Diterbitkan 2017-10-01
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  12. 12
    Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial [version 2; referees: 2 approved]

    Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial [version 2; referees: 2 approved] oleh Antony J. Cutler, Joao Oliveira, Ricardo C. Ferreira, Ben Challis, Neil M. Walker, Sarah Caddy, Jia Lu, Helen E. Stevens, Deborah J. Smyth, Marcin L. Pekalski, Jane Kennet, Kara M.D. Hunter, Ian Goodfellow, Linda S. Wicker, John A. Todd, Frank Waldron-Lynch

    Diterbitkan 2017-07-01
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  13. 13
    Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

    Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping. oleh Chris Wallace, Antony J Cutler, Nikolas Pontikos, Marcin L Pekalski, Oliver S Burren, Jason D Cooper, Arcadio Rubio García, Ricardo C Ferreira, Hui Guo, Neil M Walker, Deborah J Smyth, Stephen S Rich, Suna Onengut-Gumuscu, Stephen J Sawcer, Maria Ban, Sylvia Richardson, John A Todd, Linda S Wicker

    Diterbitkan 2015-06-01
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  14. 14
    Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression

    Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression oleh Ricardo C. Ferreira, Xaquin Castro Dopico, João J. Oliveira, Daniel B. Rainbow, Jennie H. Yang, Dominik Trzupek, Sarah A. Todd, Mhairi McNeill, Maristella Steri, Valeria Orrù, Edoardo Fiorillo, Daniel J. M. Crouch, Marcin L. Pekalski, Francesco Cucca, Francesco Cucca, Tim I. Tree, Tim J. Vyse, Linda S. Wicker, John A. Todd

    Diterbitkan 2019-11-01
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  15. 15
    IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.

    IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. oleh Lisa M Maier, Christopher E Lowe, Jason Cooper, Kate Downes, David E Anderson, Christopher Severson, Pamela M Clark, Brian Healy, Neil Walker, Cristin Aubin, Jorge R Oksenberg, Stephen L Hauser, Alistair Compston, Stephen Sawcer, International Multiple Sclerosis Genetics Consortium, Philip L De Jager, Linda S Wicker, John A Todd, David A Hafler

    Diterbitkan 2009-01-01
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  16. 16
    Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73

    Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73 oleh Lorna B. Jarvis, Daniel B. Rainbow, Valerie Coppard, Sarah K. Howlett, Zoya Georgieva, Jessica L. Davies, Harpreet Kaur Mullay, Joanna Hester, Tom Ashmore, Aletta Van Den Bosch, James T. Grist, Alasdair J. Coles, Hani S. Mousa, Stefano Pluchino, Krishnaa T. Mahbubani, Julian L. Griffin, Kourosh Saeb-Parsy, Fadi Issa, Luca Peruzzotti-Jametti, Linda S. Wicker, Joanne L. Jones

    Diterbitkan 2021-10-01
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  17. 17
    Chromosome contacts in activated T cells identify autoimmune disease candidate genes

    Chromosome contacts in activated T cells identify autoimmune disease candidate genes oleh Oliver S. Burren, Arcadio Rubio García, Biola-Maria Javierre, Daniel B. Rainbow, Jonathan Cairns, Nicholas J. Cooper, John J. Lambourne, Ellen Schofield, Xaquin Castro Dopico, Ricardo C. Ferreira, Richard Coulson, Frances Burden, Sophia P. Rowlston, Kate Downes, Steven W. Wingett, Mattia Frontini, Willem H. Ouwehand, Peter Fraser, Mikhail Spivakov, John A. Todd, Linda S. Wicker, Antony J. Cutler, Chris Wallace

    Diterbitkan 2017-09-01
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  18. 18
    Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.

    Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial. oleh John A Todd, Marina Evangelou, Antony J Cutler, Marcin L Pekalski, Neil M Walker, Helen E Stevens, Linsey Porter, Deborah J Smyth, Daniel B Rainbow, Ricardo C Ferreira, Laura Esposito, Kara M D Hunter, Kevin Loudon, Kathryn Irons, Jennie H Yang, Charles J M Bell, Helen Schuilenburg, James Heywood, Ben Challis, Sankalpa Neupane, Pamela Clarke, Gillian Coleman, Sarah Dawson, Donna Goymer, Katerina Anselmiova, Jane Kennet, Judy Brown, Sarah L Caddy, Jia Lu, Jane Greatorex, Ian Goodfellow, Chris Wallace, Tim I Tree, Mark Evans, Adrian P Mander, Simon Bond, Linda S Wicker, Frank Waldron-Lynch

    Diterbitkan 2016-10-01
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