Hasil Pencarian - Lee L Rubin

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  1. 1
    MAP4K4 Activation Mediates Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis

    MAP4K4 Activation Mediates Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis oleh Chen Wu, Michelle E. Watts, Lee L. Rubin

    Diterbitkan 2019-01-01
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  2. 2
    Suppression of MAP4K4 Signaling Ameliorates Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis-Molecular Studies Toward New Therapeutics

    Suppression of MAP4K4 Signaling Ameliorates Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis-Molecular Studies Toward New Therapeutics oleh Michelle E Watts, Chen Wu, Lee L Rubin

    Diterbitkan 2019-07-01
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  3. 3
    GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis

    GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis oleh Brittany A. Mayweather, Sean M. Buchanan, Lee L. Rubin

    Diterbitkan 2021-09-01
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  4. 4
    Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets

    Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets oleh Michelle E. Watts, Michelle E. Watts, Richard M. Giadone, Richard M. Giadone, Alban Ordureau, Kristina M. Holton, Kristina M. Holton, J. Wade Harper, Lee L. Rubin, Lee L. Rubin

    Diterbitkan 2024-01-01
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  5. 5
    Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells.

    Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryoni... oleh Cameron Sadegh, Wataru Ebina, Anthony C Arvanites, Lance S Davidow, Lee L Rubin, Jeffrey D Macklis

    Diterbitkan 2021-01-01
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  6. 6
    Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology.

    Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology. oleh Jolanta Idkowiak-Baldys, Uma Santhanam, Sean M Buchanan, Kathleen Lindahl Pfaff, Lee L Rubin, John Lyga

    Diterbitkan 2019-01-01
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  7. 7
    Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging

    Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging oleh Martin L. Tomov, Alison O’Neil, Hamdah S. Abbasi, Beth A. Cimini, Anne E. Carpenter, Lee L. Rubin, Mark Bathe

    Diterbitkan 2021-06-01
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  8. 8
    Systemic nature of spinal muscular atrophy revealed by studying insurance claims.

    Systemic nature of spinal muscular atrophy revealed by studying insurance claims. oleh Scott L Lipnick, Denis M Agniel, Rahul Aggarwal, Nina R Makhortova, Samuel G Finlayson, Alexandra Brocato, Nathan Palmer, Basil T Darras, Isaac Kohane, Lee L Rubin

    Diterbitkan 2019-01-01
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  9. 9
    Pro-myogenic small molecules revealed by a chemical screen on primary muscle stem cells

    Pro-myogenic small molecules revealed by a chemical screen on primary muscle stem cells oleh Sean M. Buchanan, Feodor D. Price, Alessandra Castiglioni, Amanda Wagner Gee, Joel Schneider, Mark N. Matyas, Monica Hayhurst, Mohammadsharif Tabebordbar, Amy J. Wagers, Lee L. Rubin

    Diterbitkan 2020-10-01
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  10. 10
    Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway

    Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway oleh Barak Blum, Adam N Roose, Ornella Barrandon, René Maehr, Anthony C Arvanites, Lance S Davidow, Jeffrey C Davis, Quinn P Peterson, Lee L Rubin, Douglas A Melton

    Diterbitkan 2014-09-01
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  11. 11
    Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy

    Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy oleh Melissa B. Walsh, Eva Janzen, Emily Wingrove, Seyyedmohsen Hosseinibarkooie, Natalia Rodriguez Muela, Lance Davidow, Maria Dimitriadi, Erika M. Norabuena, Lee L. Rubin, Brunhilde Wirth, Anne C. Hart

    Diterbitkan 2020-09-01
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  12. 12
    A microengineered Brain-Chip to model neuroinflammation in humans

    A microengineered Brain-Chip to model neuroinflammation in humans oleh Iosif Pediaditakis, Konstantia R. Kodella, Dimitris V. Manatakis, Christopher Y. Le, Sonalee Barthakur, Alexander Sorets, Achille Gravanis, Lorna Ewart, Lee L. Rubin, Elias S. Manolakos, Christopher D. Hinojosa, Katia Karalis

    Diterbitkan 2022-08-01
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  13. 13
    CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus

    CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus oleh Yassemi Koutmani, Ioannis A. Gampierakis, Alexia Polissidis, Methodios Ximerakis, Paraskevi N. Koutsoudaki, Alexandros Polyzos, George Agrogiannis, Sevasti Karaliota, Dimitra Thomaidou, Lee L. Rubin, Panagiotis K. Politis, Katia P. Karalis

    Diterbitkan 2019-10-01
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  14. 14
    Large-Scale Production of Mature Neurons from Human Pluripotent Stem Cells in a Three-Dimensional Suspension Culture System

    Large-Scale Production of Mature Neurons from Human Pluripotent Stem Cells in a Three-Dimensional Suspension Culture System oleh Alessandra Rigamonti, Giuliana G. Repetti, Chicheng Sun, Feodor D. Price, Danielle C. Reny, Francesca Rapino, Karen Weisinger, Chen Benkler, Quinn P. Peterson, Lance S. Davidow, Emil M. Hansson, Lee L. Rubin

    Diterbitkan 2016-06-01
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  15. 15
    Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption

    Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption oleh Iosif Pediaditakis, Konstantia R. Kodella, Dimitris V. Manatakis, Christopher Y. Le, Chris D. Hinojosa, William Tien-Street, Elias S. Manolakos, Kostas Vekrellis, Geraldine A. Hamilton, Lorna Ewart, Lee L. Rubin, Katia Karalis

    Diterbitkan 2021-10-01
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  16. 16
    Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons

    Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons oleh Tim Ahfeldt, Alban Ordureau, Christina Bell, Lily Sarrafha, Chicheng Sun, Silvia Piccinotti, Tobias Grass, Gustavo M. Parfitt, Joao A. Paulo, Fumiki Yanagawa, Takayuki Uozumi, Yasujiro Kiyota, J. Wade Harper, Lee L. Rubin

    Diterbitkan 2020-01-01
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  17. 17
    Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1

    Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1 oleh Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R. Klim, A. Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S. Lopes, Karolyn Sassi Ogliari, Luis A. Williams, Matthew Shear, Lee L. Rubin, Kevin Eggan, Qiao Zhou

    Diterbitkan 2017-08-01
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  18. 18
    High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly

    High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly oleh Martin H Berryer, Gizem Rizki, Anna Nathanson, Jenny A Klein, Darina Trendafilova, Sara G Susco, Daisy Lam, Angelica Messana, Kristina M Holton, Kyle W Karhohs, Beth A Cimini, Kathleen Pfaff, Anne E Carpenter, Lee L Rubin, Lindy E Barrett

    Diterbitkan 2023-04-01
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  19. 19
    Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells

    Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells oleh Martin H. Berryer, Matthew Tegtmeyer, Loïc Binan, Vera Valakh, Anna Nathanson, Darina Trendafilova, Ethan Crouse, Jenny A. Klein, Daniel Meyer, Olli Pietiläinen, Francesca Rapino, Samouil L. Farhi, Lee L. Rubin, Steven A. McCarroll, Ralda Nehme, Lindy E. Barrett

    Diterbitkan 2023-07-01
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  20. 20
    Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease

    Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease oleh Natalia Rodriguez-Muela, Nadia K. Litterman, Erika M. Norabuena, Jesse L. Mull, Maria José Galazo, Chicheng Sun, Shi-Yan Ng, Nina R. Makhortova, Andrew White, Maureen M. Lynes, Wendy K. Chung, Lance S. Davidow, Jeffrey D. Macklis, Lee L. Rubin

    Diterbitkan 2017-02-01
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