Hasil Pencarian - Laurent Meijer

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  1. 1
    Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinases (DYRKs) and cdc2-Like Kinases (CLKs) in Human Disease, an Overview

    Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinases (DYRKs) and cdc2-Like Kinases (CLKs) in Human Disease, an Overview oleh Mattias F. Lindberg, Laurent Meijer

    Diterbitkan 2021-06-01
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  2. 2
    The protein kinase CK1: Inhibition, activation, and possible allosteric modulation

    The protein kinase CK1: Inhibition, activation, and possible allosteric modulation oleh Yashoda Krishna Sunkari, Laurent Meijer, Marc Flajolet

    Diterbitkan 2022-08-01
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  3. 3
    An Overview of In Vivo and In Vitro Models for Autosomal Dominant Polycystic Kidney Disease: A Journey from 3D-Cysts to Mini-Pigs

    An Overview of In Vivo and In Vitro Models for Autosomal Dominant Polycystic Kidney Disease: A Journey from 3D-Cysts to Mini-Pigs oleh Svenja Koslowski, Camille Latapy, Pierrïck Auvray, Marc Blondel, Laurent Meijer

    Diterbitkan 2020-06-01
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  4. 4
    Synthesis of Thiazolo[5,4-f]quinazolin-9(8H)-ones as Multi-Target Directed Ligands of Ser/Thr Kinases

    Synthesis of Thiazolo[5,4-f]quinazolin-9(8H)-ones as Multi-Target Directed Ligands of Ser/Thr Kinases oleh Damien Hédou, Julien Godeau, Nadège Loaëc, Laurent Meijer, Corinne Fruit, Thierry Besson

    Diterbitkan 2016-04-01
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  5. 5
    Synthesis of Bioactive 2-(Arylamino)thiazolo[5,4-f]-quinazolin-9-ones via the Hügershoff Reaction or Cu- Catalyzed Intramolecular C-S Bond Formation

    Synthesis of Bioactive 2-(Arylamino)thiazolo[5,4-f]-quinazolin-9-ones via the Hügershoff Reaction or Cu- Catalyzed Intramolecular C-S Bond Formation oleh Damien Hédou, Carole Dubouilh-Benard, Nadège Loaëc, Laurent Meijer, Corinne Fruit, Thierry Besson

    Diterbitkan 2016-06-01
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  6. 6
    Non-Linear Pharmacokinetics of Oral Roscovitine (Seliciclib) in Cystic Fibrosis Patients Chronically Infected with <i>Pseudomonas aeruginosa</i>: A Study on Population Pharmacokinetics with Monte Carlo Simulations

    Non-Linear Pharmacokinetics of Oral Roscovitine (Seliciclib) in Cystic Fibrosis Patients Chronically Infected with <i>Pseudomonas aeruginosa</i>: A Study on Population Pharmacokine... oleh Cyril Leven, Sacha Schutz, Marie-Pierre Audrezet, Emmanuel Nowak, Laurent Meijer, Tristan Montier

    Diterbitkan 2020-11-01
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  7. 7
    A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene-1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives

    A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene-1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives oleh Jean Pierre Bazureau, Laurent Meijer, Olivier Lozach, Ludovic Paquin, Khadidja Bourahla, François Carreaux

    Diterbitkan 2011-08-01
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  8. 8
    Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models.

    Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models. oleh Bénédicte Menn, Stéphane Bach, Teri L Blevins, Mark Campbell, Laurent Meijer, Serge Timsit

    Diterbitkan 2010-08-01
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  9. 9
    Indole-3-Carbonitriles as DYRK1A Inhibitors by Fragment-Based Drug Design

    Indole-3-Carbonitriles as DYRK1A Inhibitors by Fragment-Based Drug Design oleh Rosanna Meine, Walter Becker, Hannes Falke, Lutz Preu, Nadège Loaëc, Laurent Meijer, Conrad Kunick

    Diterbitkan 2018-01-01
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  10. 10
    A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back to Conjugation-Induced Stiffenings/Loosenings of Rotational Barriers?

    A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back... oleh Krystel El Hage, Jean-Philip Piquemal, Nassima Oumata, Laurent Meijer, Hervé Galons, Nohad Gresh

    Diterbitkan 2017-07-01
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  11. 11
    Combined Virtual and Experimental Screening for CK1 Inhibitors Identifies a Modulator of p53 and Reveals Important Aspects of in Silico Screening Performance

    Combined Virtual and Experimental Screening for CK1 Inhibitors Identifies a Modulator of p53 and Reveals Important Aspects of in Silico Screening Performance oleh Vassilios Myrianthopoulos, Olivier Lozach, Danae Zareifi, Leonidas Alexopoulos, Laurent Meijer, Vassilis G. Gorgoulis, Emmanuel Mikros

    Diterbitkan 2017-10-01
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  12. 12
    (R)-Roscovitine and CFTR modulators enhance killing of multi-drug resistant Burkholderia cenocepacia by cystic fibrosis macrophages

    (R)-Roscovitine and CFTR modulators enhance killing of multi-drug resistant Burkholderia cenocepacia by cystic fibrosis macrophages oleh Chandra L. Shrestha, Shuzhong Zhang, Benjamin Wisniewski, Stephanie Häfner, Jonathan Elie, Laurent Meijer, Benjamin T. Kopp

    Diterbitkan 2020-12-01
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  13. 13
    Several Human Cyclin-Dependent Kinase Inhibitors, Structurally Related to Roscovitine, As New Anti-Malarial Agents

    Several Human Cyclin-Dependent Kinase Inhibitors, Structurally Related to Roscovitine, As New Anti-Malarial Agents oleh Sandrine Houzé, Nha-Thu Hoang, Olivier Lozach, Jacques Le Bras, Laurent Meijer, Hervé Galons, Luc Demange

    Diterbitkan 2014-09-01
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  14. 14
    Exploring Kinase Inhibition Properties of 9<i>H</i>-pyrimido[5,4-<i>b</i>]- and [4,5-<i>b</i>]indol-4-amine Derivatives

    Exploring Kinase Inhibition Properties of 9<i>H</i>-pyrimido[5,4-<i>b</i>]- and [4,5-<i>b</i>]indol-4-amine Derivatives oleh Yvonnick Loidreau, Carole Dubouilh-Benard, Marie-Renée Nourrisson, Nadège Loaëc, Laurent Meijer, Thierry Besson, Pascal Marchand

    Diterbitkan 2020-05-01
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  15. 15
    Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype.

    Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype. oleh Anne Walter, Apirat Chaikuad, Renate Helmer, Nadège Loaëc, Lutz Preu, Ingo Ott, Stefan Knapp, Laurent Meijer, Conrad Kunick

    Diterbitkan 2018-01-01
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  16. 16
    Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part I

    Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part I oleh Alicia Foucourt, Damien Hédou, Carole Dubouilh-Benard, Laurent Désiré, Anne-Sophie Casagrande, Bertrand Leblond, Nadège Loäec, Laurent Meijer, Thierry Besson

    Diterbitkan 2014-09-01
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  17. 17
    Novel Adociaquinone Derivatives from the Indonesian Sponge Xestospongia sp.

    Novel Adociaquinone Derivatives from the Indonesian Sponge Xestospongia sp. oleh Fei He, Linh H. Mai, Arlette Longeon, Brent R. Copp, Nadège Loaëc, Amandine Bescond, Laurent Meijer, Marie-Lise Bourguet-Kondracki

    Diterbitkan 2015-04-01
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  18. 18
    Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

    Anticancer Alkaloid Lamellarins Inhibit Protein Kinases oleh Laurent Meijer, Masatomo Iwao, Fumito Ishibashi, Somsak Rucirawat, Poonsakdi Ploypradith, Olivier Lozach, Yoan Ferandin, Nolwenn Trinkler, Dianne Baunbæk

    Diterbitkan 2008-10-01
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  19. 19
    Development of Kinase Inhibitors via Metal-Catalyzed C–H Arylation of 8-Alkyl-thiazolo[5,4-f]-quinazolin-9-ones Designed by Fragment-Growing Studies

    Development of Kinase Inhibitors via Metal-Catalyzed C–H Arylation of 8-Alkyl-thiazolo[5,4-f]-quinazolin-9-ones Designed by Fragment-Growing Studies oleh Florence Couly, Marine Harari, Carole Dubouilh-Benard, Laetitia Bailly, Emilie Petit, Julien Diharce, Pascal Bonnet, Laurent Meijer, Corinne Fruit, Thierry Besson

    Diterbitkan 2018-08-01
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  20. 20
    A Collection of Bioactive Nitrogen-Containing Molecules from the Marine Sponge <i>Acanthostrongylophora ingens</i>

    A Collection of Bioactive Nitrogen-Containing Molecules from the Marine Sponge <i>Acanthostrongylophora ingens</i> oleh Germana Esposito, Linh H. Mai, Arlette Longeon, Alfonso Mangoni, Emilie Durieu, Laurent Meijer, Rob Van Soest, Valeria Costantino, Marie-Lise Bourguet-Kondracki

    Diterbitkan 2019-08-01
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