Hasil Pencarian - Laura Ferraiuolo

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  1. 1
    A High-throughput and Pathophysiologically Relevant Astrocyte-motor Neuron Co-culture Assay for Amyotrophic Lateral Sclerosis Therapeutic Discovery

    A High-throughput and Pathophysiologically Relevant Astrocyte-motor Neuron Co-culture Assay for Amyotrophic Lateral Sclerosis Therapeutic Discovery oleh Matthew Stopford, Scott Allen, Laura Ferraiuolo

    Diterbitkan 2019-09-01
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  2. 2
    Blood–Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders

    Blood–Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders oleh Ana Aragón-González, Pamela J. Shaw, Laura Ferraiuolo

    Diterbitkan 2022-12-01
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  3. 3
    A Parkinson’s Disease-relevant Mitochondrial and Neuronal Morphology High-throughput Screening Assay in LUHMES Cells

    A Parkinson’s Disease-relevant Mitochondrial and Neuronal Morphology High-throughput Screening Assay in LUHMES Cells oleh Tom Leah, Irina Vazquez Villasenor, Laura Ferraiuolo, Stephen Wharton, Heather Mortiboys

    Diterbitkan 2021-01-01
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  4. 4
    Editorial: The role of glial cells in neurodegeneration

    Editorial: The role of glial cells in neurodegeneration oleh Piera Pasinelli, Kathrin Meyer, Kathrin Meyer, Laura Ferraiuolo, Robert A. Culibrk, Rita Sattler

    Diterbitkan 2024-01-01
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  5. 5
    Emerging Mechanisms Underpinning Neurophysiological Impairments in C9ORF72 Repeat Expansion-Mediated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

    Emerging Mechanisms Underpinning Neurophysiological Impairments in C9ORF72 Repeat Expansion-Mediated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia oleh Iris-Stefania Pasniceanu, Manpreet Singh Atwal, Cleide Dos Santos Souza, Laura Ferraiuolo, Matthew R. Livesey

    Diterbitkan 2021-12-01
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  6. 6
    Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS

    Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS oleh Yuri Ciervo, Noemi Gatto, Chloe Allen, Andrew Grierson, Laura Ferraiuolo, Richard J. Mead, Pamela J. Shaw

    Diterbitkan 2021-06-01
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  7. 7
    Mitochondrial Dysfunction in Alzheimer’s Disease: A Biomarker of the Future?

    Mitochondrial Dysfunction in Alzheimer’s Disease: A Biomarker of the Future? oleh Simon M. Bell, Katy Barnes, Matteo De Marco, Pamela J. Shaw, Laura Ferraiuolo, Daniel J. Blackburn, Annalena Venneri, Heather Mortiboys

    Diterbitkan 2021-01-01
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  8. 8
    Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons

    Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons oleh Aurelie Schwartzentruber, Camilla Boschian, Fernanda Martins Lopes, Monika A. Myszczynska, Elizabeth J. New, Julien Beyrath, Jan Smeitink, Laura Ferraiuolo, Heather Mortiboys

    Diterbitkan 2020-09-01
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  9. 9
    MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis.

    MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis. oleh Kelly E Glajch, Laura Ferraiuolo, Kaly A Mueller, Matthew J Stopford, Varsha Prabhkar, Achille Gravanis, Pamela J Shaw, Ghazaleh Sadri-Vakili

    Diterbitkan 2016-01-01
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  10. 10
    Towards 3D Bioprinted Spinal Cord Organoids

    Towards 3D Bioprinted Spinal Cord Organoids oleh Yilin Han, Marianne King, Evgenii Tikhomirov, Povilas Barasa, Cleide Dos Santos Souza, Jonas Lindh, Daiva Baltriukiene, Laura Ferraiuolo, Mimoun Azzouz, Maurizio R. Gullo, Elena N. Kozlova

    Diterbitkan 2022-05-01
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  11. 11
    Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS

    Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS oleh Francesca Provenzano, Sophie Nyberg, Debora Giunti, Carola Torazza, Benedetta Parodi, Tiziana Bonifacino, Cesare Usai, Nicole Kerlero de Rosbo, Marco Milanese, Antonio Uccelli, Pamela J. Shaw, Laura Ferraiuolo, Giambattista Bonanno

    Diterbitkan 2022-12-01
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  12. 12
    Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALSResearch in context

    Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALSResearch in context oleh André Varcianna, Monika A. Myszczynska, Lydia M. Castelli, Brendan O'Neill, Yeseul Kim, Jordan Talbot, Sophie Nyberg, Immanuelle Nyamali, Paul R. Heath, Matthew J. Stopford, Guillaume M. Hautbergue, Laura Ferraiuolo

    Diterbitkan 2019-02-01
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  13. 13
    C9ORF72 patient-derived endothelial cells drive blood-brain barrier disruption and contribute to neurotoxicity

    C9ORF72 patient-derived endothelial cells drive blood-brain barrier disruption and contribute to neurotoxicity oleh Ana Aragón-González, Allan C Shaw, Jannigje R Kok, Florence S Roussel, Cleide dos Santos Souza, Sarah M Granger, Tatyana Vetter, Yolanda de Diego, Kathrin C Meyer, Selina N Beal, Pamela J Shaw, Laura Ferraiuolo

    Diterbitkan 2024-04-01
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  14. 14
    Astrocytic C–X–C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity

    Astrocytic C–X–C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity oleh Beatriz G. Perez-Nievas, Louisa Johnson, Paula Beltran-Lobo, Martina M. Hughes, Luciana Gammallieri, Francesca Tarsitano, Monika A. Myszczynska, Irina Vazquez-Villasenor, Maria Jimenez-Sanchez, Claire Troakes, Stephen B. Wharton, Laura Ferraiuolo, Wendy Noble

    Diterbitkan 2021-12-01
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  15. 15
    Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS

    Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS oleh Tommaso Iannitti, Joseph M. Scarrott, Shibi Likhite, Ian R.P. Coldicott, Katherine E. Lewis, Paul R. Heath, Adrian Higginbottom, Monika A. Myszczynska, Marta Milo, Guillaume M. Hautbergue, Kathrin Meyer, Brian K. Kaspar, Laura Ferraiuolo, Pamela J. Shaw, Mimoun Azzouz

    Diterbitkan 2018-09-01
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  16. 16
    Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation

    Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation oleh Claudia S. Bauer, Claudia S. Bauer, Christopher P. Webster, Christopher P. Webster, Allan C. Shaw, Allan C. Shaw, Jannigje R. Kok, Jannigje R. Kok, Lydia M. Castelli, Lydia M. Castelli, Ya-Hui Lin, Ya-Hui Lin, Emma F. Smith, Emma F. Smith, Francisco Illanes-Álvarez, Francisco Illanes-Álvarez, Adrian Higginbottom, Adrian Higginbottom, Pamela J. Shaw, Pamela J. Shaw, Mimoun Azzouz, Mimoun Azzouz, Laura Ferraiuolo, Laura Ferraiuolo, Guillaume M. Hautbergue, Guillaume M. Hautbergue, Andrew J. Grierson, Andrew J. Grierson, Kurt J. De Vos, Kurt J. De Vos

    Diterbitkan 2022-12-01
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  17. 17
    Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).

    Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS). oleh Laura E Cox, Laura Ferraiuolo, Emily F Goodall, Paul R Heath, Adrian Higginbottom, Heather Mortiboys, Hannah C Hollinger, Judith A Hartley, Alice Brockington, Christine E Burness, Karen E Morrison, Stephen B Wharton, Andrew J Grierson, Paul G Ince, Janine Kirby, Pamela J Shaw

    Diterbitkan 2010-03-01
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  18. 18
    SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis

    SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis oleh Lydia M. Castelli, Luisa Cutillo, Cleide Dos Santos Souza, Alvaro Sanchez-Martinez, Ilaria Granata, Ya-Hui Lin, Monika A. Myszczynska, Paul R. Heath, Matthew R. Livesey, Ke Ning, Mimoun Azzouz, Pamela J. Shaw, Mario R. Guarracino, Alexander J. Whitworth, Laura Ferraiuolo, Marta Milo, Guillaume M. Hautbergue

    Diterbitkan 2021-08-01
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  19. 19
    SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

    SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits oleh Guillaume M. Hautbergue, Lydia M. Castelli, Laura Ferraiuolo, Alvaro Sanchez-Martinez, Johnathan Cooper-Knock, Adrian Higginbottom, Ya-Hui Lin, Claudia S. Bauer, Jennifer E. Dodd, Monika A. Myszczynska, Sarah M. Alam, Pierre Garneret, Jayanth S. Chandran, Evangelia Karyka, Matthew J. Stopford, Emma F. Smith, Janine Kirby, Kathrin Meyer, Brian K. Kaspar, Adrian M. Isaacs, Sherif F. El-Khamisy, Kurt J. De Vos, Ke Ning, Mimoun Azzouz, Alexander J. Whitworth, Pamela J. Shaw

    Diterbitkan 2017-07-01
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  20. 20
    Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis

    Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis oleh Calum Harvey, Marcel Weinreich, James A.K. Lee, Allan C. Shaw, Laura Ferraiuolo, Heather Mortiboys, Sai Zhang, Paul J. Hop, Ramona A.J. Zwamborn, Kristel van Eijk, Thomas H. Julian, Tobias Moll, Alfredo Iacoangeli, Ahmad Al Khleifat, John P. Quinn, Abigail L. Pfaff, Sulev Kõks, Joanna Poulton, Stephanie L. Battle, Dan E. Arking, Michael P. Snyder, Jan H. Veldink, Kevin P. Kenna, Pamela J. Shaw, Johnathan Cooper-Knock

    Diterbitkan 2024-02-01
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