Hasil Pencarian - Larissa M Podust

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  1. 1
    Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.

    Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole. oleh Chiung-Kuang Chen, Siegfried S F Leung, Christophe Guilbert, Matthew P Jacobson, James H McKerrow, Larissa M Podust

    Diterbitkan 2010-04-01
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  2. 2
    Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri.

    Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. oleh Wenxu Zhou, Anjan Debnath, Gareth Jennings, Hye Jee Hahn, Boden H Vanderloop, Minu Chaudhuri, W David Nes, Larissa M Podust

    Diterbitkan 2018-09-01
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  3. 3
    The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development.

    The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development. oleh Peter D Ziniel, Bhargava Karumudi, Andrew H Barnard, Ethan M S Fisher, Gregory R J Thatcher, Larissa M Podust, David L Williams

    Diterbitkan 2015-12-01
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  4. 4
    Correction: The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development.

    Correction: The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development. oleh Peter D Ziniel, Bhargava Karumudi, Andrew H Barnard, Ethan M S Fisher, Gregory R J Thatcher, Larissa M Podust, David L Williams

    Diterbitkan 2016-02-01
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  5. 5
    Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit.

    Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit. oleh Chiung-Kuang Chen, Patricia S Doyle, Liudmila V Yermalitskaya, Zachary B Mackey, Kenny K H Ang, James H McKerrow, Larissa M Podust

    Diterbitkan 2009-01-01
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  6. 6
    CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).

    CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). oleh Anjan Debnath, Claudia M Calvet, Gareth Jennings, Wenxu Zhou, Alexander Aksenov, Madeline R Luth, Ruben Abagyan, W David Nes, James H McKerrow, Larissa M Podust

    Diterbitkan 2017-12-01
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  7. 7
    Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51.

    Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51. oleh Shamila S Gunatilleke, Claudia M Calvet, Jonathan B Johnston, Chiung-Kuang Chen, Grigori Erenburg, Jiri Gut, Juan C Engel, Kenny K H Ang, Joseph Mulvaney, Steven Chen, Michelle R Arkin, James H McKerrow, Larissa M Podust

    Diterbitkan 2012-01-01
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  8. 8
    Targeting Ergosterol biosynthesis in Leishmania donovani: essentiality of sterol 14 alpha-demethylase.

    Targeting Ergosterol biosynthesis in Leishmania donovani: essentiality of sterol 14 alpha-demethylase. oleh Laura-Isobel McCall, Amale El Aroussi, Jun Yong Choi, Debora F Vieira, Geraldine De Muylder, Jonathan B Johnston, Steven Chen, Danielle Kellar, Jair L Siqueira-Neto, William R Roush, Larissa M Podust, James H McKerrow

    Diterbitkan 2015-03-01
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  9. 9
    4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection.

    4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi inf... oleh Claudia Magalhaes Calvet, Jun Yong Choi, Diane Thomas, Brian Suzuki, Ken Hirata, Sharon Lostracco-Johnson, Liliane Batista de Mesquita, Alanderson Nogueira, Marcelo Meuser-Batista, Tatiana Araujo Silva, Jair Lage Siqueira-Neto, William R Roush, Mirian Claudia de Souza Pereira, James H McKerrow, Larissa M Podust

    Diterbitkan 2017-12-01
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  10. 10
    Chemical–biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target

    Chemical–biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target oleh Jonathan W. Choy, Clifford Bryant, Claudia M. Calvet, Patricia S. Doyle, Shamila S. Gunatilleke, Siegfried S. F. Leung, Kenny K. H. Ang, Steven Chen, Jiri Gut, Juan A. Oses-Prieto, Jonathan B. Johnston, Michelle R. Arkin, Alma L. Burlingame, Jack Taunton, Matthew P. Jacobson, James M. McKerrow, Larissa M. Podust, Adam R. Renslo

    Diterbitkan 2013-01-01
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