Hasil Pencarian - Lamya S. Shihabuddin

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  1. 1
    Astrocyte transduction is required for rescue of behavioral phenotypes in the YAC128 mouse model with AAV-RNAi mediated HTT lowering therapeutics

    Astrocyte transduction is required for rescue of behavioral phenotypes in the YAC128 mouse model with AAV-RNAi mediated HTT lowering therapeutics oleh Lisa M. Stanek, Jie Bu, Lamya S. Shihabuddin

    Diterbitkan 2019-09-01
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  2. 2
    Sterol auto-oxidation adversely affects human motor neuron viability and is a neuropathological feature of amyotrophic lateral sclerosis

    Sterol auto-oxidation adversely affects human motor neuron viability and is a neuropathological feature of amyotrophic lateral sclerosis oleh James C. Dodge, Jinlong Yu, S. Pablo Sardi, Lamya S. Shihabuddin

    Diterbitkan 2021-01-01
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  3. 3
    Viral delivery of a microRNA to Gba to the mouse central nervous system models neuronopathic Gaucher disease

    Viral delivery of a microRNA to Gba to the mouse central nervous system models neuronopathic Gaucher disease oleh Kasey L. Jackson, Catherine Viel, Jennifer Clarke, Jie Bu, Monyrath Chan, Bing Wang, Lamya S. Shihabuddin, S. Pablo Sardi

    Diterbitkan 2019-10-01
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  4. 4
    Comparative analysis of acid sphingomyelinase distribution in the CNS of rats and mice following intracerebroventricular delivery.

    Comparative analysis of acid sphingomyelinase distribution in the CNS of rats and mice following intracerebroventricular delivery. oleh Christopher M Treleaven, Thomas Tamsett, Jonathan A Fidler, Tatyana V Taksir, Seng H Cheng, Lamya S Shihabuddin, James C Dodge

    Diterbitkan 2011-01-01
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  5. 5
    The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites

    The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites oleh Rikke Hahn Kofoed, Kate Noseworthy, Kathleen Wu, Shuruthisai Sivadas, Lisa Stanek, Bradford Elmer, Kullervo Hynynen, Lamya S. Shihabuddin, Isabelle Aubert

    Diterbitkan 2022-12-01
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  6. 6
    Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer’s disease

    Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer’... oleh James C. Dodge, Thomas J. Tamsett, Christopher M. Treleaven, Tatyana V. Taksir, Peter Piepenhagen, S. Pablo Sardi, Seng H. Cheng, Lamya S. Shihabuddin

    Diterbitkan 2022-02-01
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  7. 7
    Preclinical pharmacology of glucosylceramide synthase inhibitor venglustat in a GBA-related synucleinopathy model

    Preclinical pharmacology of glucosylceramide synthase inhibitor venglustat in a GBA-related synucleinopathy model oleh Catherine Viel, Jennifer Clarke, Can Kayatekin, Amy M. Richards, Ming Sum R. Chiang, Hyejung Park, Bing Wang, Lamya S. Shihabuddin, S. Pablo Sardi

    Diterbitkan 2021-10-01
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  8. 8
    Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease

    Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease oleh Piotr Hadaczek, Lisa Stanek, Agnieszka Ciesielska, Vivek Sudhakar, Lluis Samaranch, Philip Pivirotto, John Bringas, Catherine O'Riordan, Bryan Mastis, Waldy San Sebastian, John Forsayeth, Seng H Cheng, Krystof S Bankiewicz, Lamya S Shihabuddin

    Diterbitkan 2016-01-01
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  9. 9
    Glucosylceramide in cerebrospinal fluid of patients with GBA-associated and idiopathic Parkinson’s disease enrolled in PPMI

    Glucosylceramide in cerebrospinal fluid of patients with GBA-associated and idiopathic Parkinson’s disease enrolled in PPMI oleh Young Eun Huh, Hyejung Park, Ming Sum Ruby Chiang, Idil Tuncali, Ganqiang Liu, Joseph J. Locascio, Julia Shirvan, Samantha J. Hutten, Melissa S. Rotunno, Catherine Viel, Lamya S. Shihabuddin, Bing Wang, Sergio Pablo Sardi, Clemens R. Scherzer

    Diterbitkan 2021-11-01
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  10. 10
    Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice

    Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice oleh Bibiana K.Y. Wong, Dagmar E. Ehrnhoefer, Rona K. Graham, Dale D.O. Martin, Safia Ladha, Valeria Uribe, Lisa M. Stanek, Sonia Franciosi, Xiaofan Qiu, Yu Deng, Vlad Kovalik, Weining Zhang, Mahmoud A. Pouladi, Lamya S. Shihabuddin, Michael R. Hayden

    Diterbitkan 2015-04-01
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