Hasil Pencarian - Karl F Hoffmann

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  1. 1
    Cross-disciplinary approaches for measuring parasitic helminth viability and phenotype

    Cross-disciplinary approaches for measuring parasitic helminth viability and phenotype oleh Emily Peak, Karl F Hoffmann

    Diterbitkan 2011-06-01
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  2. 2
    Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability.

    Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability. oleh Emily Peak, Iain W Chalmers, Karl F Hoffmann

    Diterbitkan 2010-07-01
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  3. 3
    Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities [version 2; peer review: 1 approved, 2 approved with reservations]

    Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities [version 2; peer review: 1 approved, 2 approved with reservations... oleh Gilda Padalino, Iain W. Chalmers, Andrea Brancale, Karl F. Hoffmann

    Diterbitkan 2020-11-01
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  4. 4
    Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities [version 1; peer review: 1 approved, 2 approved with reservations]

    Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities [version 1; peer review: 1 approved, 2 approved with reservations... oleh Gilda Padalino, Iain W. Chalmers, Andrea Brancale, Karl F. Hoffmann

    Diterbitkan 2020-07-01
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  5. 5
    Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

    Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni oleh Gilda Padalino, Salvatore Ferla, Andrea Brancale, Iain W. Chalmers, Karl F. Hoffmann

    Diterbitkan 2018-12-01
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  6. 6
    Identification of anti-schistosomal, anthelmintic and anti-parasitic compounds curated and text-mined from the scientific literature [version 1; peer review: 2 approved]

    Identification of anti-schistosomal, anthelmintic and anti-parasitic compounds curated and text-mined from the scientific literature [version 1; peer review: 2 approved] oleh Noel M. O'Boyle, Gilda Padalino, Matthew Berriman, Karl F. Hoffmann, Avril Coghlan

    Diterbitkan 2022-07-01
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  7. 7
    The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepatica.

    The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepatica. oleh Jennifer Edwards, Martha Brown, Emily Peak, Barbara Bartholomew, Robert J Nash, Karl F Hoffmann

    Diterbitkan 2015-03-01
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  8. 8
    Using ChEMBL to Complement Schistosome Drug Discovery

    Using ChEMBL to Complement Schistosome Drug Discovery oleh Gilda Padalino, Avril Coghlan, Giampaolo Pagliuca, Josephine E. Forde-Thomas, Matthew Berriman, Karl F. Hoffmann

    Diterbitkan 2023-04-01
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  9. 9
    Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni.

    Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni. oleh Kathrin K Geyer, Sabrina E Munshi, Helen L Whiteland, Narcis Fernandez-Fuentes, Dylan W Phillips, Karl F Hoffmann

    Diterbitkan 2018-06-01
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  10. 10
    Use of genomic DNA as an indirect reference for identifying gender-associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae.

    Use of genomic DNA as an indirect reference for identifying gender-associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae. oleh Jennifer M Fitzpatrick, Anna V Protasio, Andrew J McArdle, Gary A Williams, David A Johnston, Karl F Hoffmann

    Diterbitkan 2008-01-01
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  11. 11
    The Anti-mycobacterial Activity of a Diterpenoid-Like Molecule Operates Through Nitrogen and Amino Acid Starvation

    The Anti-mycobacterial Activity of a Diterpenoid-Like Molecule Operates Through Nitrogen and Amino Acid Starvation oleh Alessandra Crusco, Alessandra Crusco, Rafael Baptista, Sumana Bhowmick, Manfred Beckmann, Luis A. J. Mur, Andrew D. Westwell, Karl F. Hoffmann

    Diterbitkan 2019-06-01
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  12. 12
    Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni.

    Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni. oleh Holly M Craven, Riccardo Bonsignore, Vasilis Lenis, Nicolo Santi, Daniel Berrar, Martin Swain, Helen Whiteland, Angela Casini, Karl F Hoffmann

    Diterbitkan 2021-02-01
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  13. 13
    Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses.

    Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses. oleh Jennifer M Fitzpatrick, Emily Peak, Samirah Perally, Iain W Chalmers, John Barrett, Timothy P Yoshino, Alasdair C Ivens, Karl F Hoffmann

    Diterbitkan 2009-11-01
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  14. 14
    Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal.

    Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal. oleh Helen Whiteland, Alessandra Crusco, Lisa W Bloemberg, Jamie Tibble-Howlings, Josephine Forde-Thomas, Avril Coghlan, Patrick J Murphy, Karl F Hoffmann

    Diterbitkan 2020-10-01
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  15. 15
    The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities

    The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities oleh Kathrin K. Geyer, Sabrina E. Munshi, Martin Vickers, Michael Squance, Toby J. Wilkinson, Daniel Berrar, Cristian Chaparro, Martin T. Swain, Karl F. Hoffmann

    Diterbitkan 2018-08-01
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  16. 16
    The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses.

    The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses. oleh Colin M Fitzsimmons, Frances M Jones, Alex Stearn, Iain W Chalmers, Karl F Hoffmann, Jakub Wawrzyniak, Shona Wilson, Narcis B Kabatereine, David W Dunne

    Diterbitkan 2012-01-01
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  17. 17
    Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni.

    Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni. oleh David Roquis, Aaron Taudt, Kathrin K Geyer, Gilda Padalino, Karl F Hoffmann, Nancy Holroyd, Matt Berriman, Benoît Aliaga, Cristian Chaparro, Christoph Grunau, Ronaldo de Carvalho Augusto

    Diterbitkan 2018-05-01
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  18. 18
    The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.

    The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets. oleh Kezia C L Whatley, Gilda Padalino, Helen Whiteland, Kathrin K Geyer, Benjamin J Hulme, Iain W Chalmers, Josephine Forde-Thomas, Salvatore Ferla, Andrea Brancale, Karl F Hoffmann

    Diterbitkan 2019-11-01
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  19. 19
    Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni

    Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni oleh Fanny C. Nowacki, Martin T. Swain, Oleg I. Klychnikov, Umar Niazi, Alasdair Ivens, Juan F. Quintana, Paul J. Hensbergen, Cornelis H. Hokke, Amy H. Buck, Karl F. Hoffmann

    Diterbitkan 2015-10-01
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  20. 20
    Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae.

    Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae. oleh Thomas A Gasan, Marije E Kuipers, Grisial H Roberts, Gilda Padalino, Josephine E Forde-Thomas, Shona Wilson, Jakub Wawrzyniak, Edridah M Tukahebwa, Karl F Hoffmann, Iain W Chalmers

    Diterbitkan 2021-11-01
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