Hasil Pencarian - Jules A. A. C. Heuberger

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  1. 1
    Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders

    Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders oleh Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld

    Diterbitkan 2021-02-01
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  2. 2
    Repeatability and predictive value of lactate threshold concepts in endurance sports.

    Repeatability and predictive value of lactate threshold concepts in endurance sports. oleh Jules A A C Heuberger, Pim Gal, Frederik E Stuurman, Wouter A S de Muinck Keizer, Yuri Mejia Miranda, Adam F Cohen

    Diterbitkan 2018-01-01
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  3. 3
    Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double‐blind placebo‐controlled cross‐over study

    Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double‐blind placebo‐controlled cross‐over study oleh Titia Q. Ruijs, Ingrid W. Koopmans, Marieke L. deKam, Martijn R. Tannemaat, Geert Jan Groeneveld, Jules A. A. C. Heuberger

    Diterbitkan 2022-12-01
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  4. 4
    A leucine‐rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls

    A leucine‐rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls oleh Maurits F. J. M. Vissers, Matthew D. Troyer, Eva Thijssen, Diana R. Pereira, | Jules A. A. C. Heuberger, Geert Jan Groeneveld, Sarah Huntwork‐Rodriguez

    Diterbitkan 2023-08-01
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  5. 5
    Acute retigabine‐induced effects on myelinated motor axons in amyotrophic lateral sclerosis

    Acute retigabine‐induced effects on myelinated motor axons in amyotrophic lateral sclerosis oleh Boudewijn T. H. M. Sleutjes, Diederik J. L. Stikvoort García, Maria O. Kovalchuk, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Hessel Franssen, Leonard H. van denBerg

    Diterbitkan 2022-08-01
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  6. 6
    Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-tolerant patients.

    Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-toler... oleh Laurence M Moss, Marijke Hyke Algera, Robert Dobbins, Frank Gray, Stephanie Strafford, Amy Heath, Monique van Velzen, Jules A A C Heuberger, Marieke Niesters, Erik Olofsen, Celine M Laffont, Albert Dahan, Geert Jan Groeneveld

    Diterbitkan 2022-01-01
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  7. 7
    EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis

    EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis oleh Daniel Hidalgo, Jacob Bejder, Ramona Pop, Kyle Gellatly, Yung Hwang, S. Maxwell Scalf, Anna E. Eastman, Jane-Jane Chen, Lihua Julie Zhu, Jules A. A. C. Heuberger, Shangqin Guo, Mark J. Koury, Nikolai Baastrup Nordsborg, Merav Socolovsky

    Diterbitkan 2021-12-01
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  8. 8
    Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation

    Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation oleh Patricio O’Donnell, Francis M. Dijkstra, Ugur Damar, Lei Quanhong, Annika A. de Goede, Lin Xu, Andres Pascual-Leone, Derek L. Buhl, Rob Zuiker, Titia Q. Ruijs, Jules A. A. C. Heuberger, Paul MacMullin, Martin Lubell, Mahnaz Asgharnejad, Venkatesha Murthy, Alexander Rotenberg, Gabriel E. Jacobs, Laura Rosen

    Diterbitkan 2021-05-01
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  9. 9
    Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo‐controlled, double‐blind phase I/Ib studies in healthy subjects and patients

    Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo‐controlled, double‐blind phase I/Ib... oleh Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn, Salah Hadi, Jeffrey Harris, Richard M. Tsai, Andres Cruz‐Herranz, Fen Huang, Vincent Tong, Rebecca Erickson, Yuda Zhu, Kimberly Scearce‐Levie, Jennifer Hsiao‐Nakamoto, Xinyan Tang, Megan Chang, Brian M. Fox, Anthony A. Estrada, Robert J. Pomponio, Miguel Alonso‐Alonso, Moshe Zilberstein, Nazem Atassi, Matthew D. Troyer, Carole Ho

    Diterbitkan 2022-08-01
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