Hasil Pencarian - Jukka‐Pekka Mecklin

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  1. 1
    Clinical characteristics of pancreatic and biliary tract cancers in Lynch syndrome: A retrospective analysis from the Finnish National Lynch Syndrome Research Registry

    Clinical characteristics of pancreatic and biliary tract cancers in Lynch syndrome: A retrospective analysis from the Finnish National Lynch Syndrome Research Registry oleh Kristina Zalevskaja, Kristina Zalevskaja, Jukka-Pekka Mecklin, Jukka-Pekka Mecklin, Toni T. Seppälä, Toni T. Seppälä

    Diterbitkan 2023-02-01
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  2. 2
    Novel insights into tumorigenesis revealed by molecular analysis of Lynch syndrome cases with multiple colorectal tumors

    Novel insights into tumorigenesis revealed by molecular analysis of Lynch syndrome cases with multiple colorectal tumors oleh Alisa Olkinuora, Satu Mäki-Nevala, Sanjeevi Ukwattage, Ari Ristimäki, Ari Ristimäki, Maarit Ahtiainen, Jukka-Pekka Mecklin, Jukka-Pekka Mecklin, Päivi Peltomäki, Päivi Peltomäki

    Diterbitkan 2024-04-01
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  3. 3
    Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women with lynch syndrome

    Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women with lynch syndrome oleh Mari Kalamo, Johanna Mäenpää, Toni Seppälä, Jukka-Pekka Mecklin, Kirsi Pylvänäinen, Synnöve Staff

    Diterbitkan 2021-09-01
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  4. 4
    Circulating metabolome landscape in Lynch syndrome

    Circulating metabolome landscape in Lynch syndrome oleh Tiina A. Jokela, Jari E. Karppinen, Minta Kärkkäinen, Jukka-Pekka Mecklin, Simon Walker, Toni T. Seppälä, Eija K. Laakkonen

    Diterbitkan 2024-02-01
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  5. 5
    Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer

    Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer oleh Kyösti Tahkola, Maarit Ahtiainen, Jukka-Pekka Mecklin, Ilmo Kellokumpu, Johanna Laukkarinen, Markku Tammi, Raija Tammi, Juha P. Väyrynen, Jan Böhm

    Diterbitkan 2021-06-01
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  6. 6
    High immune cell infiltration predicts improved survival in cholangiocarcinoma

    High immune cell infiltration predicts improved survival in cholangiocarcinoma oleh Erkki-Ville Wirta, Erkki-Ville Wirta, Säde Szeto, Hanna Koppatz, Arno Nordin, Arno Nordin, Heikki Mäkisalo, Heikki Mäkisalo, Johanna Arola, Jukka Sirén, Maarit Ahtiainen, Jan Böhm, Jukka-Pekka Mecklin, Jukka-Pekka Mecklin, Ville Sallinen, Ville Sallinen, Toni T. Seppälä, Toni T. Seppälä, Toni T. Seppälä, Toni T. Seppälä

    Diterbitkan 2024-05-01
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  7. 7
    The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription

    The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription oleh Wael M. Abdel-Rahman, Johanna E. Lotsari-Salomaa, Sippy Kaur, Anni Niskakoski, Sakari Knuutila, Heikki Järvinen, Jukka-Pekka Mecklin, Päivi Peltomäki

    Diterbitkan 2016-01-01
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  8. 8
    Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

    Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis oleh Satu Mäki-Nevala, Sanjeevi Ukwattage, Erkki-Ville Wirta, Maarit Ahtiainen, Ari Ristimäki, Toni T. Seppälä, Anna Lepistö, Jukka-Pekka Mecklin, Päivi Peltomäki

    Diterbitkan 2021-09-01
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  9. 9
    A comparative pan-genome perspective of niche-adaptable cell-surface protein phenotypes in Lactobacillus rhamnosus.

    A comparative pan-genome perspective of niche-adaptable cell-surface protein phenotypes in Lactobacillus rhamnosus. oleh Ravi Kant, Johanna Rintahaka, Xia Yu, Pia Sigvart-Mattila, Lars Paulin, Jukka-Pekka Mecklin, Maria Saarela, Airi Palva, Ingemar von Ossowski

    Diterbitkan 2014-01-01
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  10. 10
    DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expressionResearch in context

    DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expressionResearch in context oleh Satu Mäki-Nevala, Satu Valo, Ari Ristimäki, Virinder Sarhadi, Sakari Knuutila, Minna Nyström, Laura Renkonen-Sinisalo, Anna Lepistö, Jukka-Pekka Mecklin, Päivi Peltomäki

    Diterbitkan 2019-01-01
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  11. 11
    Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesisResearch in context

    Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesisResearch in context oleh Marjaana Pussila, Aleksi Laiho, Petri Törönen, Pauliina Björkbacka, Sonja Nykänen, Kirsi Pylvänäinen, Liisa Holm, Jukka-Pekka Mecklin, Laura Renkonen-Sinisalo, Taru Lehtonen, Anna Lepistö, Jere Linden, Satu Mäki-Nevala, Päivi Peltomäki, Minna Nyström

    Diterbitkan 2024-05-01
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  12. 12
    Exome-wide somatic mutation characterization of small bowel adenocarcinoma.

    Exome-wide somatic mutation characterization of small bowel adenocarcinoma. oleh Ulrika A Hänninen, Riku Katainen, Tomas Tanskanen, Roosa-Maria Plaketti, Riku Laine, Jiri Hamberg, Ari Ristimäki, Eero Pukkala, Minna Taipale, Jukka-Pekka Mecklin, Linda M Forsström, Esa Pitkänen, Kimmo Palin, Niko Välimäki, Netta Mäkinen, Lauri A Aaltonen

    Diterbitkan 2018-03-01
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  13. 13
    Eleven candidate susceptibility genes for common familial colorectal cancer.

    Eleven candidate susceptibility genes for common familial colorectal cancer. oleh Alexandra E Gylfe, Riku Katainen, Johanna Kondelin, Tomas Tanskanen, Tatiana Cajuso, Ulrika Hänninen, Jussi Taipale, Minna Taipale, Laura Renkonen-Sinisalo, Heikki Järvinen, Jukka-Pekka Mecklin, Outi Kilpivaara, Esa Pitkänen, Pia Vahteristo, Sari Tuupanen, Auli Karhu, Lauri A Aaltonen

    Diterbitkan 2013-01-01
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  14. 14
    Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

    Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival oleh Tatiana Cajuso, Päivi Sulo, Tomas Tanskanen, Riku Katainen, Aurora Taira, Ulrika A. Hänninen, Johanna Kondelin, Linda Forsström, Niko Välimäki, Mervi Aavikko, Eevi Kaasinen, Ari Ristimäki, Selja Koskensalo, Anna Lepistö, Laura Renkonen-Sinisalo, Toni Seppälä, Teijo Kuopio, Jan Böhm, Jukka-Pekka Mecklin, Outi Kilpivaara, Esa Pitkänen, Kimmo Palin, Lauri A. Aaltonen

    Diterbitkan 2019-09-01
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  15. 15
    The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution

    The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution oleh Alexej Ballhausen, Moritz Jakob Przybilla, Michael Jendrusch, Saskia Haupt, Elisabeth Pfaffendorf, Florian Seidler, Johannes Witt, Alejandro Hernandez Sanchez, Katharina Urban, Markus Draxlbauer, Sonja Krausert, Aysel Ahadova, Martin Simon Kalteis, Pauline L. Pfuderer, Daniel Heid, Damian Stichel, Johannes Gebert, Maria Bonsack, Sarah Schott, Hendrik Bläker, Toni Seppälä, Jukka-Pekka Mecklin, Sanne Ten Broeke, Maartje Nielsen, Vincent Heuveline, Julia Krzykalla, Axel Benner, Angelika Beate Riemer, Magnus von Knebel Doeberitz, Matthias Kloor

    Diterbitkan 2020-09-01
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  16. 16
    Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer

    Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer oleh Johanna Kondelin, Kari Salokas, Lilli Saarinen, Kristian Ovaska, Heli Rauanheimo, Roosa‐Maria Plaketti, Jiri Hamberg, Xiaonan Liu, Leena Yadav, Alexandra E Gylfe, Tatiana Cajuso, Ulrika A Hänninen, Kimmo Palin, Heikki Ristolainen, Riku Katainen, Eevi Kaasinen, Tomas Tanskanen, Mervi Aavikko, Minna Taipale, Jussi Taipale, Laura Renkonen‐Sinisalo, Anna Lepistö, Selja Koskensalo, Jan Böhm, Jukka‐Pekka Mecklin, Halit Ongen, Emmanouil T Dermitzakis, Outi Kilpivaara, Pia Vahteristo, Mikko Turunen, Sampsa Hautaniemi, Sari Tuupanen, Auli Karhu, Niko Välimäki, Markku Varjosalo, Esa Pitkänen, Lauri A Aaltonen

    Diterbitkan 2018-09-01
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  17. 17
    Contribution of allelic imbalance to colorectal cancer

    Contribution of allelic imbalance to colorectal cancer oleh Kimmo Palin, Esa Pitkänen, Mikko Turunen, Biswajyoti Sahu, Päivi Pihlajamaa, Teemu Kivioja, Eevi Kaasinen, Niko Välimäki, Ulrika A. Hänninen, Tatiana Cajuso, Mervi Aavikko, Sari Tuupanen, Outi Kilpivaara, Linda van den Berg, Johanna Kondelin, Tomas Tanskanen, Riku Katainen, Marta Grau, Heli Rauanheimo, Roosa-Maria Plaketti, Aurora Taira, Päivi Sulo, Tuomo Hartonen, Kashyap Dave, Bernhard Schmierer, Sandeep Botla, Maria Sokolova, Anna Vähärautio, Kornelia Gladysz, Halit Ongen, Emmanouil Dermitzakis, Jesper Bertram Bramsen, Torben Falck Ørntoft, Claus Lindbjerg Andersen, Ari Ristimäki, Anna Lepistö, Laura Renkonen-Sinisalo, Jukka-Pekka Mecklin, Jussi Taipale, Lauri A. Aaltonen

    Diterbitkan 2018-09-01
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  18. 18
    Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report

    Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report oleh Toni Seppälä, Kirsi Pylvänäinen, Dafydd Gareth Evans, Heikki Järvinen, Laura Renkonen-Sinisalo, Inge Bernstein, Elke Holinski-Feder, Paola Sala, Annika Lindblom, Finlay Macrae, Ignacio Blanco, Rolf Sijmons, Jacqueline Jeffries, Hans Vasen, John Burn, Sigve Nakken, Eivind Hovig, Einar Andreas Rødland, Kukatharmini Tharmaratnam, Wouter H. de Vos tot Nederveen Cappel, James Hill, Juul Wijnen, Mark Jenkins, Maurizio Genuardi, Kate Green, Fiona Lalloo, Lone Sunde, Miriam Mints, Lucio Bertario, Marta Pineda, Matilde Navarro, Monika Morak, Ian M. Frayling, John-Paul Plazzer, Julian R. Sampson, Gabriel Capella, Gabriela Möslein, Jukka-Pekka Mecklin, Pål Møller, in collaboration with The Mallorca Group

    Diterbitkan 2017-10-01
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  19. 19
    Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report

    Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report oleh Mev Dominguez-Valentin, Toni T. Seppälä, Julian R. Sampson, Finlay Macrae, Ingrid Winship, D. Gareth Evans, Rodney J. Scott, John Burn, Gabriela Möslein, Inge Bernstein, Kirsi Pylvänäinen, Laura Renkonen-Sinisalo, Anna Lepistö, Annika Lindblom, John-Paul Plazzer, Douglas Tjandra, Huw Thomas, Kate Green, Fiona Lalloo, Emma J. Crosbie, James Hill, Gabriel Capella, Marta Pineda, Matilde Navarro, Joan Brunet Vidal, Karina Rønlund, Randi Thyregaard Nielsen, Mette Yilmaz, Louise Laurberg Elvang, Lior Katz, Maartje Nielsen, Sanne W. ten Broeke, Sigve Nakken, Eivind Hovig, Lone Sunde, Matthias Kloor, Magnus v Knebel Doeberitz, Aysel Ahadova, Noralane Lindor, Verena Steinke-Lange, Elke Holinski-Feder, Jukka-Pekka Mecklin, Pål Møller

    Diterbitkan 2019-10-01
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  20. 20
    Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

    Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report oleh Toni T. Seppälä, Aysel Ahadova, Mev Dominguez-Valentin, Finlay Macrae, D. Gareth Evans, Christina Therkildsen, Julian Sampson, Rodney Scott, John Burn, Gabriela Möslein, Inge Bernstein, Elke Holinski-Feder, Kirsi Pylvänäinen, Laura Renkonen-Sinisalo, Anna Lepistö, Charlotte Kvist Lautrup, Annika Lindblom, John-Paul Plazzer, Ingrid Winship, Douglas Tjandra, Lior H. Katz, Stefan Aretz, Robert Hüneburg, Stefanie Holzapfel, Karl Heinimann, Adriana Della Valle, Florencia Neffa, Nathan Gluck, Wouter H. de Vos tot Nederveen Cappel, Hans Vasen, Monika Morak, Verena Steinke-Lange, Christoph Engel, Nils Rahner, Wolff Schmiegel, Deepak Vangala, Huw Thomas, Kate Green, Fiona Lalloo, Emma J. Crosbie, James Hill, Gabriel Capella, Marta Pineda, Matilde Navarro, Ignacio Blanco, Sanne ten Broeke, Maartje Nielsen, Ken Ljungmann, Sigve Nakken, Noralane Lindor, Ian Frayling, Eivind Hovig, Lone Sunde, Matthias Kloor, Jukka-Pekka Mecklin, Mette Kalager, Pål Møller

    Diterbitkan 2019-02-01
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