Hasil Pencarian - Joshua E Allen

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  1. 1
    Correction: First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent.

    Correction: First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent. oleh Joshua E Allen, Roslyn N Crowder, Wafik S El-Deiry

    Diterbitkan 2016-01-01
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  2. 2
    First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent.

    First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent. oleh Joshua E Allen, Roslyn N Crowder, Wafik S El-Deiry

    Diterbitkan 2015-01-01
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  3. 3
    Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway

    Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway oleh Joshua E Allen, Gabriel Krigsfeld, Luv Patel, Patrick A Mayes, David T Dicker, Gen Sheng Wu, Wafik S El-Deiry

    Diterbitkan 2024-10-01
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  4. 4
    The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer.

    The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer. oleh Joshua E Allen, Jean-Nicolas Gallant, David T Dicker, Shantu Amin, Rosalyn B Irby, Arun K Sharma, Wafik S El-Deiry

    Diterbitkan 2013-01-01
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  5. 5
    Correction: The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer.

    Correction: The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer. oleh Joshua E. Allen, Jean-Nicolas Gallant, David T. Dicker, Shantu Amin, Rosalyn B. Irby, Arun K. Sharma, Wafik S. El-Deiry

    Diterbitkan 2013-01-01
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  6. 6
    Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis.

    Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis. oleh Junaid Abdulghani, Joshua E Allen, David T Dicker, Yingqiu Yvette Liu, David Goldenberg, Charles D Smith, Robin Humphreys, Wafik S El-Deiry

    Diterbitkan 2013-01-01
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  7. 7
    A Bayesian machine learning approach for drug target identification using diverse data types

    A Bayesian machine learning approach for drug target identification using diverse data types oleh Neel S. Madhukar, Prashant K. Khade, Linda Huang, Kaitlyn Gayvert, Giuseppe Galletti, Martin Stogniew, Joshua E. Allen, Paraskevi Giannakakou, Olivier Elemento

    Diterbitkan 2019-11-01
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  8. 8
    Role of Dopamine Receptors in the Anticancer Activity of ONC201

    Role of Dopamine Receptors in the Anticancer Activity of ONC201 oleh Christina Leah B. Kline, Marie D. Ralff, Amriti R. Lulla, Jessica M. Wagner, Phillip H. Abbosh, David T. Dicker, Joshua E. Allen, Wafik S. El-Deiry

    Diterbitkan 2018-01-01
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  9. 9
    The Imipridone ONC201 Induces Apoptosis and Overcomes Chemotherapy Resistance by Up-Regulation of Bim in Multiple Myeloma

    The Imipridone ONC201 Induces Apoptosis and Overcomes Chemotherapy Resistance by Up-Regulation of Bim in Multiple Myeloma oleh Yong-sheng Tu, Jin He, Huan Liu, Hans C. Lee, Hua Wang, Jo Ishizawa, Joshua E. Allen, Michael Andreeff, Robert Z. Orlowski, Richard E. Davis, Jing Yang

    Diterbitkan 2017-10-01
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  10. 10
    ONC201/TIC10 Is Empowered by 2-Deoxyglucose and Causes Metabolic Reprogramming in Medulloblastoma Cells in Vitro Independent of C-Myc Expression

    ONC201/TIC10 Is Empowered by 2-Deoxyglucose and Causes Metabolic Reprogramming in Medulloblastoma Cells in Vitro Independent of C-Myc Expression oleh Annika Dwucet, Maximilian Pruss, Qiyu Cao, Mine Tanriover, Varun V. Prabhu, Joshua E. Allen, Aurelia Peraud, Mike-Andrew Westhoff, Markus D. Siegelin, Christian Rainer Wirtz, Georg Karpel-Massler

    Diterbitkan 2021-11-01
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  11. 11
    A novel dopamine receptor D2 antagonist (ONC206) potentiates the effects of olaparib in endometrial cancer

    A novel dopamine receptor D2 antagonist (ONC206) potentiates the effects of olaparib in endometrial cancer oleh Sarah E. Paraghamian, Jianqing Qiu, Gabrielle M. Hawkins, Ziyi Zhao, Wenchuan Sun, Yali Fan, Xin Zhang, Hongyan Suo, Tianran Hao, Varun Vijay Prabhu, Joshua E. Allen, Chunxiao Zhou, Victoria Bae-Jump

    Diterbitkan 2023-12-01
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  12. 12
    Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells

    Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells oleh Francesca Amoroso, Kimberley Glass, Reema Singh, Francisco Liberal, Rebecca E. Steele, Sarah Maguire, Rohinton Tarapore, Joshua E. Allen, Sandra Van Schaeybroeck, Karl T. Butterworth, Kevin Prise, Joe M. O’Sullivan, Suneil Jain, David J. Waugh, Ian G. Mills

    Diterbitkan 2021-02-01
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  13. 13
    ONC206, an Imipridone Derivative, Induces Cell Death Through Activation of the Integrated Stress Response in Serous Endometrial Cancer In Vitro

    ONC206, an Imipridone Derivative, Induces Cell Death Through Activation of the Integrated Stress Response in Serous Endometrial Cancer In Vitro oleh Yingao Zhang, Yingao Zhang, Yu Huang, Yu Huang, Yajie Yin, Yali Fan, Yali Fan, Wenchuan Sun, Xiaoling Zhao, Xiaoling Zhao, Katherine Tucker, Allison Staley, Sarah Paraghamian, Gabrielle Hawkins, Varun Prabhu, Joshua E. Allen, Chunxiao Zhou, Chunxiao Zhou, Victoria Bae-Jump, Victoria Bae-Jump

    Diterbitkan 2020-10-01
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  14. 14
    Anti-Tumor and Anti-Invasive Effects of ONC201 on Ovarian Cancer Cells and a Transgenic Mouse Model of Serous Ovarian Cancer

    Anti-Tumor and Anti-Invasive Effects of ONC201 on Ovarian Cancer Cells and a Transgenic Mouse Model of Serous Ovarian Cancer oleh Yali Fan, Yali Fan, Jiandong Wang, Ziwei Fang, Ziwei Fang, Stuart R. Pierce, Lindsay West, Allison Staley, Katherine Tucker, Yajie Yin, Wenchuan Sun, Weimin Kong, Varun Prabhu, Joshua E. Allen, Chunxiao Zhou, Chunxiao Zhou, Victoria L. Bae-Jump, Victoria L. Bae-Jump

    Diterbitkan 2022-03-01
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  15. 15
    Targeting dopamine receptor D2 as a novel therapeutic strategy in endometrial cancer

    Targeting dopamine receptor D2 as a novel therapeutic strategy in endometrial cancer oleh Stuart R. Pierce, Ziwei Fang, Yajie Yin, Lindsay West, Majdouline Asher, Tianran Hao, Xin Zhang, Katherine Tucker, Allison Staley, Yali Fan, Wenchuan Sun, Dominic T. Moore, Chang Xu, Yi-Hsuan Tsai, Joel Parker, Varun Vijay Prabhu, Joshua E. Allen, Douglas Lee, Chunxiao Zhou, Victoria Bae-Jump

    Diterbitkan 2021-02-01
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  16. 16
    Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.

    Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors. oleh Varun V Prabhu, Amriti R Lulla, Neel S Madhukar, Marie D Ralff, Dan Zhao, Christina Leah B Kline, A Pieter J Van den Heuvel, Avital Lev, Mathew J Garnett, Ultan McDermott, Cyril H Benes, Tracy T Batchelor, Andrew S Chi, Olivier Elemento, Joshua E Allen, Wafik S El-Deiry

    Diterbitkan 2017-01-01
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  17. 17
    ONC201 and imipridones: Anti-cancer compounds with clinical efficacy

    ONC201 and imipridones: Anti-cancer compounds with clinical efficacy oleh Varun Vijay Prabhu, Sara Morrow, Abed Rahman Kawakibi, Lanlan Zhou, Marie Ralff, Jocelyn Ray, Aakash Jhaveri, Isacco Ferrarini, Young Lee, Cassandra Parker, Yiqun Zhang, Robyn Borsuk, Wen-I Chang, Joshua N. Honeyman, Fabio Tavora, Benedito Carneiro, Alexander Raufi, Kelsey Huntington, Lindsey Carlsen, Anna Louie, Howard Safran, Attila A. Seyhan, Rohinton S. Tarapore, Lee Schalop, Martin Stogniew, Joshua E. Allen, Wolfgang Oster, Wafik S. El-Deiry

    Diterbitkan 2020-12-01
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  18. 18
    Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration

    Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration oleh Mark N. Stein, Jyoti Malhotra, Rohinton S. Tarapore, Usha Malhotra, Ann W. Silk, Nancy Chan, Lorna Rodriguez, Joseph Aisner, Robert D. Aiken, Tina Mayer, Bruce G. Haffty, Jenna H. Newman, Salvatore M. Aspromonte, Praveen K. Bommareddy, Ricardo Estupinian, Charles B. Chesson, Evita T. Sadimin, Shengguo Li, Daniel J. Medina, Tracie Saunders, Melissa Frankel, Aparna Kareddula, Sherrie Damare, Elayne Wesolowsky, Christian Gabel, Wafik S. El-Deiry, Varun V. Prabhu, Joshua E. Allen, Martin Stogniew, Wolfgang Oster, Joseph R. Bertino, Steven K. Libutti, Janice M. Mehnert, Andrew Zloza

    Diterbitkan 2019-05-01
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