Hasil Pencarian - Jos Jonkers

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  1. 1
    Filling in the gaps in PARP inhibitor-induced synthetic lethality

    Filling in the gaps in PARP inhibitor-induced synthetic lethality oleh Mariana Paes Dias, Jos Jonkers

    Diterbitkan 2021-11-01
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  2. 2
    MIND the translational gap: Preclinical models of ductal carcinoma in situ

    MIND the translational gap: Preclinical models of ductal carcinoma in situ oleh Stefan J. Hutten, Jos Jonkers

    Diterbitkan 2023-08-01
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  3. 3
    Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids

    Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids oleh Mariana Paes Dias, Sven Rottenberg, Jos Jonkers

    Diterbitkan 2022-03-01
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  4. 4
    Mouse intraductal modeling of primary ductal carcinoma in situ

    Mouse intraductal modeling of primary ductal carcinoma in situ oleh Stefan J. Hutten, Fariba Behbod, Colinda L.G.J. Scheele, Jos Jonkers

    Diterbitkan 2023-09-01
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  5. 5
    Genetically engineered mouse models in oncology research and cancer medicine

    Genetically engineered mouse models in oncology research and cancer medicine oleh Kelly Kersten, Karin E de Visser, Martine H van Miltenburg, Jos Jonkers

    Diterbitkan 2016-12-01
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  6. 6
    Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

    Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach. oleh Christiaan Klijn, Jan Bot, David J Adams, Marcel Reinders, Lodewyk Wessels, Jos Jonkers

    Diterbitkan 2010-01-01
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  7. 7
    EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumors.

    EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumors. oleh Serge A L Zander, Wendy Sol, Lee Greenberger, Yixian Zhang, Olaf van Tellingen, Jos Jonkers, Piet Borst, Sven Rottenberg

    Diterbitkan 2012-01-01
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  8. 8
    Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents

    Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents oleh Nora M. Gerhards, Vincent A. Blomen, Merve Mutlu, Joppe Nieuwenhuis, Denise Howald, Charlotte Guyader, Jos Jonkers, Thijn R. Brummelkamp, Sven Rottenberg

    Diterbitkan 2018-06-01
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  9. 9
    Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice

    Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice oleh Patrick W. B. Derksen, Tanya M. Braumuller, Eline van der Burg, Marten Hornsveld, Elly Mesman, Jelle Wesseling, Paul Krimpenfort, Jos Jonkers

    Diterbitkan 2011-05-01
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  10. 10
    Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin

    Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin oleh Koen Schipper, Danielle Seinstra, Anne Paulien Drenth, Eline van der Burg, Veronika Ramovs, Arnoud Sonnenberg, Jacco van Rheenen, Micha Nethe, Jos Jonkers

    Diterbitkan 2019-08-01
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  11. 11
    Lack of genomic heterogeneity at high-resolution aCGH between primary breast cancers and their paired lymph node metastases.

    Lack of genomic heterogeneity at high-resolution aCGH between primary breast cancers and their paired lymph node metastases. oleh Marieke A Vollebergh, Christiaan Klijn, Philip C Schouten, Jelle Wesseling, Danielle Israeli, Bauke Ylstra, Lodewyk F A Wessels, Jos Jonkers, Sabine C Linn

    Diterbitkan 2014-01-01
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  12. 12
    Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression

    Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression oleh Nienke A. de Vries, Danielle Hulsman, Waseem Akhtar, Johann de Jong, Denise C. Miles, Marleen Blom, Olaf van Tellingen, Jos Jonkers, Maarten van Lohuizen

    Diterbitkan 2015-01-01
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  13. 13
    Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas

    Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas oleh Khyati Meghani, Walker Fuchs, Alexandre Detappe, Pascal Drané, Ewa Gogola, Sven Rottenberg, Jos Jonkers, Ursula Matulonis, Elizabeth M. Swisher, Panagiotis A. Konstantinopoulos, Dipanjan Chowdhury

    Diterbitkan 2018-04-01
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  14. 14
    Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS.

    Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS. oleh Tessa Buckle, Joeri Kuil, Nynke S van den Berg, Anton Bunschoten, Hildo J Lamb, Hushan Yuan, Lee Josephson, Jos Jonkers, Alexander D Borowsky, Fijs W B van Leeuwen

    Diterbitkan 2013-01-01
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  15. 15
    Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

    Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells oleh Pepijn M. Schoonen, Francien Talens, Colin Stok, Ewa Gogola, Anne Margriet Heijink, Peter Bouwman, Floris Foijer, Madalena Tarsounas, Sohvi Blatter, Jos Jonkers, Sven Rottenberg, Marcel A. T. M. van Vugt

    Diterbitkan 2017-07-01
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  16. 16
    PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma

    PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma oleh Mirjam C. Boelens, Micha Nethe, Sjoerd Klarenbeek, Julian R. de Ruiter, Eva Schut, Nicola Bonzanni, Amber L. Zeeman, Ellen Wientjens, Eline van der Burg, Lodewyk Wessels, Renée van Amerongen, Jos Jonkers

    Diterbitkan 2016-08-01
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  17. 17
    The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity

    The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity oleh Jordan R. Becker, Raquel Cuella-Martin, Marco Barazas, Rui Liu, Catarina Oliveira, Antony W. Oliver, Kirstin Bilham, Abbey B. Holt, Andrew N. Blackford, Jörg Heierhorst, Jos Jonkers, Sven Rottenberg, J. Ross Chapman

    Diterbitkan 2018-12-01
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  18. 18
    Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers

    Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers oleh Françoise Derouane, Manon Desgres, Camilla Moroni, Jérôme Ambroise, Martine Berlière, Mieke R. Van Bockstal, Christine Galant, Cédric van Marcke, Marianela Vara-Messler, Stefan J. Hutten, Jos Jonkers, Larissa Mourao, Colinda L. G. J. Scheele, Francois P. Duhoux, Cyril Corbet

    Diterbitkan 2024-02-01
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  19. 19
    Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

    Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors. oleh Christiaan Klijn, Marco J Koudijs, Jaap Kool, Jelle ten Hoeve, Mandy Boer, Joost de Moes, Waseem Akhtar, Martine van Miltenburg, Annabel Vendel-Zwaagstra, Marcel J T Reinders, David J Adams, Maarten van Lohuizen, John Hilkens, Lodewyk F A Wessels, Jos Jonkers

    Diterbitkan 2013-01-01
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  20. 20
    Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system

    Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system oleh Sjoerd Klarenbeek, Chris W. Doornebal, Sjors M. Kas, Nicola Bonzanni, Jinhyuk Bhin, Tanya M. Braumuller, Ingrid van der Heijden, Mark Opdam, Philip C. Schouten, Kelly Kersten, Roebi de Bruijn, Daniel Zingg, Julia Yemelyanenko, Lodewyk F.A. Wessels, Karin E. de Visser, Jos Jonkers

    Diterbitkan 2020-01-01
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