Hasil Pencarian - Jonathan M. Brotchie

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  1. 1
    Monoamine Reuptake Inhibitors in Parkinson’s Disease

    Monoamine Reuptake Inhibitors in Parkinson’s Disease oleh Philippe Huot, Susan H. Fox, Jonathan M. Brotchie

    Diterbitkan 2015-01-01
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  2. 2
    Towards a Non-Human Primate Model of Alpha-Synucleinopathy for Development of Therapeutics for Parkinson's Disease: Optimization of AAV1/2 Delivery Parameters to Drive Sustained Expression of Alpha Synuclein and Dopaminergic Degeneration in Macaque.

    Towards a Non-Human Primate Model of Alpha-Synucleinopathy for Development of Therapeutics for Parkinson's Disease: Optimization of AAV1/2 Delivery Parameters to Drive Sustained Ex... oleh James B Koprich, Tom H Johnston, Gabriela Reyes, Vanessa Omana, Jonathan M Brotchie

    Diterbitkan 2016-01-01
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  3. 3
    Upregulation of Striatal Preproenkephalin Gene Expression Occurs before the Appearance of Parkinsonian Signs in 1-Methyl-4-phenyl- 1,2,3,6-tetrahydropyridine Monkeys

    Upregulation of Striatal Preproenkephalin Gene Expression Occurs before the Appearance of Parkinsonian Signs in 1-Methyl-4-phenyl- 1,2,3,6-tetrahydropyridine Monkeys oleh Erwan Bezard, Paula Ravenscroft, Christian E. Gross, Alan R. Crossman, Jonathan M. Brotchie

    Diterbitkan 2001-04-01
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  4. 4
    Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease

    Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease oleh Naomi P. Visanji, Susan H. Fox, Tom Johnston, Gabriela Reyes, Mark J. Millan, Jonathan M. Brotchie

    Diterbitkan 2009-08-01
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  5. 5
    Progressive neurodegeneration or endogenous compensation in an animal model of Parkinson's disease produced by decreasing doses of alpha-synuclein.

    Progressive neurodegeneration or endogenous compensation in an animal model of Parkinson's disease produced by decreasing doses of alpha-synuclein. oleh James B Koprich, Tom H Johnston, Philippe Huot, M Gabriela Reyes, Maria Espinosa, Jonathan M Brotchie

    Diterbitkan 2011-01-01
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  6. 6
    Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease

    Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease oleh Alexander Grotemeyer, Judith F. Fischer, James B. Koprich, Jonathan M. Brotchie, Robert Blum, Jens Volkmann, Chi Wang Ip

    Diterbitkan 2023-03-01
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  7. 7
    The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson’s Disease

    The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson’s Disease oleh Simoneide S. Titze-de-Almeida, Cristina Soto-Sánchez, Eduardo Fernandez, James B. Koprich, Jonathan M. Brotchie, Ricardo Titze-de-Almeida

    Diterbitkan 2020-03-01
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  8. 8
    Toward in vivo proof of binding of 18F-labeled inhibitor [18F]TRACK to peripheral tropomyosin receptor kinases

    Toward in vivo proof of binding of 18F-labeled inhibitor [18F]TRACK to peripheral tropomyosin receptor kinases oleh Melinda Wuest, Justin J. Bailey, Jennifer Dufour, Darryl Glubrecht, Vanessa Omana, Tom H. Johnston, Jonathan M. Brotchie, Ralf Schirrmacher

    Diterbitkan 2022-07-01
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  9. 9
    Selective loss of bi-directional synaptic plasticity in the direct and indirect striatal output pathways accompanies generation of parkinsonism and l-DOPA induced dyskinesia in mouse models

    Selective loss of bi-directional synaptic plasticity in the direct and indirect striatal output pathways accompanies generation of parkinsonism and l-DOPA induced dyskinesia in mou... oleh Sherri L. Thiele, Betty Chen, Charlotte Lo, Tracey S. Gertler, Ruth Warre, James D. Surmeier, Jonathan M. Brotchie, Joanne E. Nash

    Diterbitkan 2014-11-01
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  10. 10
    The monoamine re-uptake inhibitor UWA-101 improves motor fluctuations in the MPTP-lesioned common marmoset.

    The monoamine re-uptake inhibitor UWA-101 improves motor fluctuations in the MPTP-lesioned common marmoset. oleh Philippe Huot, Tom H Johnston, Michael N Gandy, M Gabriela Reyes, Susan H Fox, Matthew J Piggott, Jonathan M Brotchie

    Diterbitkan 2012-01-01
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  11. 11
    Non-steric-zipper models for pathogenic α-synuclein conformers

    Non-steric-zipper models for pathogenic α-synuclein conformers oleh Brock Schuman, Amy Won, Koroboshka Brand-Arzamendi, James B. Koprich, Xiao-Yan Wen, Patrick A. Howson, Jonathan M. Brotchie, Christopher M. Yip

    Diterbitkan 2018-06-01
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  12. 12
    Expansion of regulatory T cells by CD28 superagonistic antibodies attenuates neurodegeneration in A53T-α-synuclein Parkinson’s disease mice

    Expansion of regulatory T cells by CD28 superagonistic antibodies attenuates neurodegeneration in A53T-α-synuclein Parkinson’s disease mice oleh Mohammad Badr, Rhonda L. McFleder, Jingjing Wu, Susanne Knorr, James B. Koprich, Thomas Hünig, Jonathan M. Brotchie, Jens Volkmann, Manfred B. Lutz, Chi Wang Ip

    Diterbitkan 2022-12-01
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  13. 13
    Altered function of glutamatergic cortico-striatal synapses causes output pathway abnormalities in a chronic model of parkinsonism

    Altered function of glutamatergic cortico-striatal synapses causes output pathway abnormalities in a chronic model of parkinsonism oleh Ruth Warre, Sherri Thiele, Sheena Talwar, Marium Kamal, Tom H. Johnston, Sharon Wang, Doris Lam, Charlotte Lo, Charline S. Khademullah, Gillian Perera, Gabriela Reyes, Xuan Sherry Sun, Jonathan M. Brotchie, Joanne E. Nash

    Diterbitkan 2011-03-01
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  14. 14
    Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice.

    Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice. oleh Greer S Kirshenbaum, Neil Dawson, Jonathan G L Mullins, Tom H Johnston, Mark J Drinkhill, Ian J Edwards, Susan H Fox, Judith A Pratt, Jonathan M Brotchie, John C Roder, Steven J Clapcote

    Diterbitkan 2013-01-01
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  15. 15
    Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein

    Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein oleh Chris McKinnon, Mitchell L. De Snoo, Elise Gondard, Clemens Neudorfer, Hien Chau, Sophie G. Ngana, Darren M. O’Hara, Jonathan M. Brotchie, James B. Koprich, Andres M. Lozano, Lorraine V. Kalia, Suneil K. Kalia

    Diterbitkan 2020-02-01
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  16. 16
    Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease

    Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease oleh Lina A. Matschke, Marlene A. Komadowski, Annette Stöhr, Bolam Lee, Martin T. Henrich, Markus Griesbach, Susanne Rinné, Fanni F. Geibl, Wei-Hua Chiu, James B. Koprich, Jonathan M. Brotchie, Aytug K. Kiper, Amalia M. Dolga, Wolfgang H. Oertel, Niels Decher

    Diterbitkan 2022-02-01
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  17. 17
    Corrigendum to “Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism” [Neurobiol. Dis. 106 (2018) 133–146]

    Corrigendum to “Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism” [Neurobiol.... oleh Jacqueline A. Gleave, Lindsay R. Arathoon, Dennison Trinh, Kristin E. Lizal, Nicolas Giguère, James E.M. Barber, Zainab Najarali, M. Hassan Khan, Sherri L. Thiele, Mahin S. Semmen, James B. Koprich, Jonathan M. Brotchie, James H. Eubanks, Louis-Eric Trudeau, Joanne E. Nash

    Diterbitkan 2018-08-01
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  18. 18
    Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism

    Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism oleh Jacqueline A. Gleave, Lindsay R. Arathoon, Dennison Trinh, Kristin E. Lizal, Nicolas Giguère, James H.M. Barber, Zainab Najarali, M. Hassan Khan, Sherri L. Thiele, Mahin S. Semmen, James B. Koprich, Jonathan M. Brotchie, James H. Eubanks, Louis-Eric Trudeau, Joanne E. Nash

    Diterbitkan 2017-10-01
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  19. 19
    Brain-to-gut trafficking of alpha-synuclein by CD11c+ cells in a mouse model of Parkinson’s disease

    Brain-to-gut trafficking of alpha-synuclein by CD11c+ cells in a mouse model of Parkinson’s disease oleh Rhonda L. McFleder, Anastasiia Makhotkina, Janos Groh, Ursula Keber, Fabian Imdahl, Josefina Peña Mosca, Alina Peteranderl, Jingjing Wu, Sawako Tabuchi, Jan Hoffmann, Ann-Kathrin Karl, Axel Pagenstecher, Jörg Vogel, Andreas Beilhack, James B. Koprich, Jonathan M. Brotchie, Antoine-Emmanuel Saliba, Jens Volkmann, Chi Wang Ip

    Diterbitkan 2023-11-01
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