Chimeric antigen receptorâengineered T cells as oncolytic virus carriers oleh Heather VanSeggelen, Daniela GM Tantalo, Arya Afsahi, Joanne A Hammill, Jonathan L Bramson

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290 IL-15 is required for optimal anti-tumor activity of Vγ9Vδ2 T cells against glioblastoma oleh Jonathan L Bramson, Arya Afsahi, Allyson E Moore, Nickolas Serniuck, Hayley Nault, Sheila K Singh

HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants oleh Andrew Nguyen, Louisa Ho, Samuel T. Workenhe, Lan Chen, Jonathan Samson, Scott R. Walsh, Jonathan Pol, Jonathan L. Bramson, Yonghong Wan

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Alterations to the frequency and function of peripheral blood monocytes and associations with chronic disease in the advanced-age, frail elderly. oleh Chris P Verschoor, Jennie Johnstone, Jamie Millar, Robin Parsons, Alina Lelic, Mark Loeb, Jonathan L Bramson, Dawn M E Bowdish

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LCL161 enhances expansion and survival of engineered anti-tumor T cells but is restricted by death signaling oleh Arya Afsahi, Arya Afsahi, Arya Afsahi, Christopher M. Silvestri, Christopher M. Silvestri, Christopher M. Silvestri, Allyson E. Moore, Allyson E. Moore, Allyson E. Moore, Carly F. Graham, Carly F. Graham, Carly F. Graham, Kaylyn Bacchiochi, Kaylyn Bacchiochi, Martine St-Jean, Christopher L. Baker, Christopher L. Baker, Christopher L. Baker, Robert G. Korneluk, Shawn T. Beug, Shawn T. Beug, Shawn T. Beug, Eric C. LaCasse, Jonathan L. Bramson, Jonathan L. Bramson, Jonathan L. Bramson

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The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age. oleh Alina Lelic, Chris P Verschoor, Mario Ventresca, Robin Parsons, Carole Evelegh, Dawn Bowdish, Michael R Betts, Mark B Loeb, Jonathan L Bramson

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Manufacturing T cells in hollow fiber membrane bioreactors changes their programming and enhances their potency oleh Seung Mi Yoo, Vivan W.C. Lau, Craig Aarts, Bojana Bojovic, Gregory Steinberg, Joanne A. Hammill, Anna Dvorkin-Gheva, Raja Ghosh, Jonathan L. Bramson

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Surface phenotype and functionality of WNV specific T cells differ with age and disease severity. oleh Paolo Piazza, Curtis P McMurtrey, Alina Lelic, Robert L Cook, Rachel Hess, Eric Yablonsky, Luann Borowski, Mark B Loeb, Jonathan L Bramson, William H Hildebrand, Charles R Rinaldo

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AMPK β1 reduces tumor progression and improves survival in p53 null mice oleh Vanessa P. Houde, Sara Donzelli, Andrea Sacconi, Sandra Galic, Joanne A. Hammill, Jonathan L. Bramson, Robert A. Foster, Theodoros Tsakiridis, Bruce E. Kemp, Giuseppe Grasso, Giovanni Blandino, Paola Muti, Gregory R. Steinberg

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The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy oleh Amr Ali, Bassem Mekhaeil, Olga-Demetra Biziotis, Evangelia E. Tsakiridis, Elham Ahmadi, Jianhan Wu, Simon Wang, Kanwaldeep Singh, Gabe Menjolian, Thomas Farrell, Aruz Mesci, Stanley Liu, Tobias Berg, Jonathan L. Bramson, Gregory R. Steinberg, Theodoros Tsakiridis

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A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity oleh Joanne A. Hammill, Jacek M. Kwiecien, Anna Dvorkin-Gheva, Vivian W.C. Lau, Christopher Baker, Ying Wu, Ksenia Bezverbnaya, Craig Aarts, Christopher W. Heslen, Galina F. Denisova, Heather Derocher, Katy Milne, Brad H. Nelson, Jonathan L. Bramson

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Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence. oleh Abhirami A Ananth, Lee-Hwa Tai, Casey Lansdell, Almohanad A Alkayyal, Katherine E Baxter, Leonard Angka, Jiqing Zhang, Christiano Tanese de Souza, Kyle B Stephenson, Kelley Parato, Jonathan L Bramson, John C Bell, Brian D Lichty, Rebecca C Auer

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Correction: Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence. oleh Abhirami A Ananth, Lee-Hwa Tai, Casey Lansdell, Almohanad A Alkayyal, Katherine E Baxter, Leonard Angka, Jiqing Zhang, Christiano Tanese de Souza, Kyle B Stephenson, Kelley Parato, Jonathan L Bramson, John C Bell, Brian D Lichty, Rebecca C Auer

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Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors oleh Ana L. Portillo, Richard Hogg, Sophie M. Poznanski, Eduardo A. Rojas, Niamh J. Cashell, Joanne A. Hammill, Marianne V. Chew, Mira M. Shenouda, Tyrah M. Ritchie, Quynh T. Cao, Jeremy A. Hirota, Sukhbinder Dhesy-Thind, Jonathan L. Bramson, Ali A. Ashkar

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Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non‐small cell lung cancer (NSCLC) through inhibition of HIF‐1α oleh Olga‐Demetra Biziotis, Evangelia Evelyn Tsakiridis, Amr Ali, Elham Ahmadi, Jianhan Wu, Simon Wang, Bassem Mekhaeil, Kanwaldeep Singh, Gabe Menjolian, Thomas Farrell, Bassam Abdulkarim, Ranjan K. Sur, Aruz Mesci, Peter Ellis, Tobias Berg, Jonathan L Bramson, Paola Muti, Gregory R Steinberg, Theodoros Tsakiridis

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The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity oleh Christopher W. Helsen, Joanne A. Hammill, Vivian W. C. Lau, Kenneth A. Mwawasi, Arya Afsahi, Ksenia Bezverbnaya, Lisa Newhook, Danielle L. Hayes, Craig Aarts, Bojana Bojovic, Galina F. Denisova, Jacek M. Kwiecien, Ian Brain, Heather Derocher, Katy Milne, Brad H. Nelson, Jonathan L. Bramson

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Metformin-induced reductions in tumor growth involves modulation of the gut microbiome oleh Lindsay A. Broadfield, Amna Saigal, Jake C. Szamosi, Joanne A. Hammill, Ksenia Bezverbnaya, Dongdong Wang, Jaya Gautam, Evangelia E. Tsakiridis, Fiorella Di Pastena, Jamie McNicol, Jianhan Wu, Saad Syed, James S.V. Lally, Amogelang R. Raphenya, Marie-Jose Blouin, Michael Pollak, Andrea Sacconi, Giovanni Blandino, Andrew G. McArthur, Jonathan D. Schertzer, Michael G. Surette, Stephen M. Collins, Jonathan L. Bramson, Paola Muti, Theodoros Tsakiridis, Gregory R. Steinberg

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Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials oleh Jonathan G. Pol, Sergio A. Acuna, Beta Yadollahi, Nan Tang, Kyle B. Stephenson, Matthew J. Atherton, David Hanwell, Alexander El-Warrak, Alyssa Goldstein, Badru Moloo, Patricia V. Turner, Roberto Lopez, Sandra LaFrance, Carole Evelegh, Galina Denisova, Robin Parsons, Jamie Millar, Gautier Stoll, Chantal G. Martin, Julia Pomoransky, Caroline J. Breitbach, Jonathan L. Bramson, John C. Bell, Yonghong Wan, David F. Stojdl, Brian D. Lichty, J. Andrea McCart

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