Hasil Pencarian - Jonathan Karn

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  1. 1
    The cell biology of HIV-1 latency and rebound

    The cell biology of HIV-1 latency and rebound oleh Uri Mbonye, Jonathan Karn

    Diterbitkan 2024-04-01
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  2. 2
    Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency

    Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency oleh Kien Nguyen, Biswajit Das, Curtis Dobrowolski, Jonathan Karn

    Diterbitkan 2017-03-01
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  3. 3
    Protocol for intracellular immunofluorescence measurements of latent HIV reactivation in a primary CD4+ T cell model

    Protocol for intracellular immunofluorescence measurements of latent HIV reactivation in a primary CD4+ T cell model oleh Uri Mbonye, Anna Agaponova, Muda Yang, Jonathan Karn

    Diterbitkan 2024-12-01
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  4. 4
    Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways.

    Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways. oleh Uri Mbonye, Konstantin Leskov, Meenakshi Shukla, Saba Valadkhan, Jonathan Karn

    Diterbitkan 2021-09-01
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  5. 5
    Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation.

    Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation. oleh Kien Nguyen, Curtis Dobrowolski, Meenakshi Shukla, Won-Kyung Cho, Benjamin Luttge, Jonathan Karn

    Diterbitkan 2021-10-01
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  6. 6
    The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency.

    The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency. oleh Zichong Li, Uri Mbonye, Zeming Feng, Xiaohui Wang, Xiang Gao, Jonathan Karn, Qiang Zhou

    Diterbitkan 2018-04-01
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  7. 7
    Entry of Polarized Effector Cells into Quiescence Forces HIV Latency

    Entry of Polarized Effector Cells into Quiescence Forces HIV Latency oleh Curtis Dobrowolski, Saba Valadkhan, Amy C. Graham, Meenakshi Shukla, Angela Ciuffi, Amalio Telenti, Jonathan Karn

    Diterbitkan 2019-04-01
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  8. 8
    Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.

    Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes. oleh Uri R Mbonye, Giridharan Gokulrangan, Manish Datt, Curtis Dobrowolski, Maxwell Cooper, Mark R Chance, Jonathan Karn

    Diterbitkan 2013-01-01
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  9. 9
    Cross-talk between microglia and neurons regulates HIV latency.

    Cross-talk between microglia and neurons regulates HIV latency. oleh David Alvarez-Carbonell, Fengchun Ye, Nirmala Ramanath, Yoelvis Garcia-Mesa, Pamela E Knapp, Kurt F Hauser, Jonathan Karn

    Diterbitkan 2019-12-01
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  10. 10
    Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells.

    Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells. oleh Fengchun Ye, David Alvarez-Carbonell, Kien Nguyen, Konstantin Leskov, Yoelvis Garcia-Mesa, Sheetal Sreeram, Saba Valadkhan, Jonathan Karn

    Diterbitkan 2022-07-01
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  11. 11
    Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA.

    Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA. oleh Matthew S Lalonde, Michael A Lobritz, Annette Ratcliff, Mastooreh Chamanian, Zafiria Athanassiou, Mudit Tyagi, Julian Wong, John A Robinson, Jonathan Karn, Gabriele Varani, Eric J Arts

    Diterbitkan 2011-05-01
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  12. 12
    Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells

    Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells oleh Harpreet Kaur, Paige Minchella, David Alvarez-Carbonell, Neeraja Purandare, Vijay K. Nagampalli, Daniel Blankenberg, Todd Hulgan, Mariana Gerschenson, Jonathan Karn, Siddhesh Aras, Asha R. Kallianpur

    Diterbitkan 2023-07-01
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  13. 13
    COVID-19 plasma exosomes promote proinflammatory immune responses in peripheral blood mononuclear cells

    COVID-19 plasma exosomes promote proinflammatory immune responses in peripheral blood mononuclear cells oleh Lechuang Chen, Rui Chen, Min Yao, Zhimin Feng, Guoxiang Yuan, Fengchun Ye, Kien Nguyen, Jonathan Karn, Grace A. McComsey, Thomas M. McIntyre, Ge Jin

    Diterbitkan 2022-12-01
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  14. 14
    Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA

    Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA oleh Lechuang Chen, Zhimin Feng, Hong Yue, Douglas Bazdar, Uri Mbonye, Chad Zender, Clifford V. Harding, Leslie Bruggeman, Jonathan Karn, Scott F. Sieg, Bingcheng Wang, Ge Jin

    Diterbitkan 2018-11-01
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  15. 15
    HIV Latency Reversing Agents have diverse effects on Natural Killer Cell Function

    HIV Latency Reversing Agents have diverse effects on Natural Killer Cell Function oleh Carolina Garrido, Carolina Garrido, Adam M Spivak, Natalia Soriano-Sarabia, Natalia Soriano-Sarabia, Mary Ann Checkley, Edward Barker, Jonathan Karn, Vicente Planelles, David M Margolis, David M Margolis, David M Margolis

    Diterbitkan 2016-09-01
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  16. 16
    Genomic profiling of HIV-1 integration in microglia cells links viral integration to the topologically associated domains

    Genomic profiling of HIV-1 integration in microglia cells links viral integration to the topologically associated domains oleh Mona Rheinberger, Ana Luisa Costa, Martin Kampmann, Dunja Glavas, Iart Luca Shytaj, Sheetal Sreeram, Carlotta Penzo, Nadine Tibroni, Yoelvis Garcia-Mesa, Konstantin Leskov, Oliver T. Fackler, Kristian Vlahovicek, Jonathan Karn, Bojana Lucic, Carl Herrmann, Marina Lusic

    Diterbitkan 2023-02-01
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  17. 17
    A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon

    A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon oleh Debjit Khan, Fulvia Terenzi, GuanQun Liu, Prabar K. Ghosh, Fengchun Ye, Kien Nguyen, Arnab China, Iyappan Ramachandiran, Shruti Chakraborty, Jennifer Stefan, Krishnendu Khan, Kommireddy Vasu, Franklin Dong, Belinda Willard, Jonathan Karn, Michaela U. Gack, Paul L. Fox

    Diterbitkan 2023-06-01
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  18. 18
    Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial.

    Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-... oleh Deepti Saxena, Michael Spino, Fernando Tricta, John Connelly, Bernadette M Cracchiolo, Axel-Rainer Hanauske, Darlene D'Alliessi Gandolfi, Michael B Mathews, Jonathan Karn, Bart Holland, Myung Hee Park, Tsafi Pe'ery, Paul E Palumbo, Hartmut M Hanauske-Abel

    Diterbitkan 2016-01-01
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  19. 19
    Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda

    Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda oleh Samira Joussef-Piña, Immaculate Nankya, Sophie Nalukwago, Joy Baseke, Sandra Rwambuya, Dane Winner, Fred Kyeyune, Keith Chervenak, Bonnie Thiel, Robert Asaad, Curtis Dobrowolski, Benjamin Luttge, Blair Lawley, Cissy M. Kityo, W. Henry Boom, Jonathan Karn, Miguel E. Quiñones-Mateu

    Diterbitkan 2022-01-01
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  20. 20
    Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress

    Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress oleh Iart Luca Shytaj, Francesco Andrea Procopio, Mohammad Tarek, Irene Carlon‐Andres, Hsin‐Yao Tang, Aaron R Goldman, MohamedHusen Munshi, Virender Kumar Pal, Mattia Forcato, Sheetal Sreeram, Konstantin Leskov, Fengchun Ye, Bojana Lucic, Nicolly Cruz, Lishomwa C Ndhlovu, Silvio Bicciato, Sergi Padilla‐Parra, Ricardo Sobhie Diaz, Amit Singh, Marina Lusic, Jonathan Karn, David Alvarez‐Carbonell, Andrea Savarino

    Diterbitkan 2021-08-01
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